but no interaction with either HBsAg or HepG2.2.15-derived HBV was detected .
In contrast , highly mannosylated HBV , <*> is recognized by DC - SIGN .
Soluble DC - SIGN and L - SIGN specifically bound HCV virus - like particles , but no interaction with either HBsAg or HepG2.2.15-derived HBV was detected .
In contrast , highly mannosylated HBV , obtained by treating HBV producing HepG2.2.15 cells with the a - mannosidase I inhibitor kifunensine , is recognized by DC - SIGN .