In this study , Lactobacillus plantarum strains NC8 and WCFS1 were used as oral delivery vehicles
Guinea pigs were orally vaccinated <*> with NC8-pSIP411 , NC8-pSIP411-VP1 , WCFS1-pSIP411 , WCFS1-pSIP411-VP1 or milk .
In this study , Lactobacillus plantarum strains NC8 and WCFS1 were used as oral delivery vehicles containing a pSIP411-VP1 recombinant plasmid to initiate mucosal and systemic immune responses in guinea pigs .
Guinea pigs were orally vaccinated ( three doses ) with NC8-pSIP411 , NC8-pSIP411-VP1 , WCFS1-pSIP411 , WCFS1-pSIP411-VP1 or milk .