In this study , we identified fexaramine as a potent inhibitor of FCV
A comparative analysis of viral resistance was also performed
In this study , we identified fexaramine as a potent inhibitor of FCV including vs - FCV strains in cell culture and demonstrated that fexaramine is a entry blocker for FCV by using various experiments including time - of - addition studies , generation of resistant viruses in cell culture and the reverse genetics system .
A comparative analysis of viral resistance was also performed using a peptidyl inhibitor ( NPI52 ) targeting FCV 3C - like protease .