Herein , the LASSBio Chemical Library is presented as a valuable source of compounds for screening
The great majority of the compounds part of this library have shown in vivo activity in animal models ,
Herein , the LASSBio Chemical Library is presented as a valuable source of compounds for screening to identify hits suitable for subsequent hit - to - lead optimization stages .
The great majority of the compounds part of this library have shown in vivo activity in animal models , which is an indication that they possess overall favorable bioavailability properties and , hence , adequate pharmacokinetic profiles .