In this study , Lactobacillus plantarum strains NC8 and WCFS1 were used as oral delivery vehicles
Animals <*> developed high levels of antigen - specific serum IgG , IgA , IgM , mucosal secretory IgA ( sIgA ) and neutralizing antibodies ,
In this study , Lactobacillus plantarum strains NC8 and WCFS1 were used as oral delivery vehicles containing a pSIP411-VP1 recombinant plasmid to initiate mucosal and systemic immune responses in guinea pigs .
Animals immunized with NC8-pSIP411-VP1 and WCFS1-pSIP411-VP1 developed high levels of antigen - specific serum IgG , IgA , IgM , mucosal secretory IgA ( sIgA ) and neutralizing antibodies , and revealed stronger cell - mediated immune responses and enhanced protection against FMDV challenge compared with control groups .