Enzymatically inactive cysteine mutants were retained in the endoplasmic reticulum
In the absence of any crystal - structure data , the demonstration <*> appears to be of particular importance .
Enzymatically inactive cysteine mutants were retained in the endoplasmic reticulum as shown by high - resolution imaging and Endoglycosidase H digestion .
In the absence of any crystal - structure data , the demonstration that individual extracellular cysteines contribute to APN expression and function appears to be of particular importance .