and upon activation , forms dimers
which assemble with MAVS , TBK-1 and IKKe ,
STING resides in the endoplasmic reticulum and upon activation , forms dimers which assemble with MAVS , TBK-1 and IKKe , leading to IRF-3 activation and subsequent induction of interferon ( IFN ) .
STING resides in the endoplasmic reticulum and upon activation , forms dimers which assemble with MAVS , TBK-1 and IKKe , leading to IRF-3 activation and subsequent induction of interferon ( IFN ) .