Feline calicivirus ( FCV ) is a small non - enveloped virus
In this study , we identified fexaramine as a potent inhibitor of FCV
Feline calicivirus ( FCV ) is a small non - enveloped virus containing a single - stranded , positive - sense RNA genome of approximately 7.7 kb .
In this study , we identified fexaramine as a potent inhibitor of FCV including vs - FCV strains in cell culture and demonstrated that fexaramine is a entry blocker for FCV by using various experiments including time - of - addition studies , generation of resistant viruses in cell culture and the reverse genetics system .