Toxicodynamic phenotyping revealed an effect of PERC on bodyweight loss , induction of peroxisome proliferator activated receptor - alpha ( PPARa)-regulated genes , and dysregulation of hepatic lipid homeostasis .
Clustering was observed among a ) liver levels of PERC , TCA , and triglycerides ; b ) TCA levels in liver and kidney ; and c ) TCA levels in serum , brain , fat , and lung .
Toxicodynamic phenotyping revealed an effect of PERC on bodyweight loss , induction of peroxisome proliferator activated receptor - alpha ( PPARa)-regulated genes , and dysregulation of hepatic lipid homeostasis .
Clustering was observed among a ) liver levels of PERC , TCA , and triglycerides ; b ) TCA levels in liver and kidney ; and c ) TCA levels in serum , brain , fat , and lung .