A central nervous system ( CNS ) disorder <*> was induced experimentally in gnotobiotic pigs by intravenous and oral or intranasal inoculation of the porcine teschovirus ( PTV ) Toyama 2002 strain
Lesions <*> were observed in the brainstem , cerebellum and spinal cord .
A central nervous system ( CNS ) disorder characterized by non - suppurative encephalomyelitis with neurological signs was induced experimentally in gnotobiotic pigs by intravenous and oral or intranasal inoculation of the porcine teschovirus ( PTV ) Toyama 2002 strain isolated from breeding pigs in Japan .
Lesions consisting of perivascular cuffing of mononuclear cells , focal gliosis , neuronal necrosis and neuronophagia were observed in the brainstem , cerebellum and spinal cord .