which in turn results in global protein synthesis inhibition and formation of stress granules ( SGs ) .
that SGs can interfere with the replicative cycle of certain viruses .
PKR phosphorylates the α subunit of eukaryotic translation initiation factor 2 ( eIF2α ) , which in turn results in global protein synthesis inhibition and formation of stress granules ( SGs ) .
Recent studies have shown that SGs can interfere with the replicative cycle of certain viruses .