that suppression of early innate immune responses through S1P 1 signaling results in reduced mortality during infection with a human pathogenic strain of influenza virus .
that diseases <*> could be chemically tractable .
Moreover , we demonstrate that suppression of early innate immune responses through S1P 1 signaling results in reduced mortality during infection with a human pathogenic strain of influenza virus .
Modulation of endothelium with a specific agonist suggests that diseases in which amplification of cytokine storm is a significant pathological component could be chemically tractable .