that the 3a protein displayed a punctate cytoplasmic localization in Drosophila as in SARS - CoV - infected cells .
We provide genetic evidence
Using a specific monoclonal antibody , we demonstrated that the 3a protein displayed a punctate cytoplasmic localization in Drosophila as in SARS - CoV - infected cells .
We provide genetic evidence to support that 3a is functionally related to clathrin - mediated endocytosis .