that FSS - targeting compounds have antiviral activity against replication - competent HIV in human cells ,
These results support the viability of the HIV-1 FSS RNA as a therapeutic target
We show for the first time that FSS - targeting compounds have antiviral activity against replication - competent HIV in human cells , including a highly cytopathic , multidrug - resistant strain .
These results support the viability of the HIV-1 FSS RNA as a therapeutic target and more generally highlight opportunities for synthetic molecule - mediated interference with protein recoding in a wide range of organisms .