The HIV-1 frameshift - stimulating ( FSS ) RNA , a regulatory RNA of critical importance in the virus ' life cycle , has been posited as a novel target for anti - HIV drug development .
We report the synthesis and evaluation of triazole - containing compounds
The HIV-1 frameshift - stimulating ( FSS ) RNA , a regulatory RNA of critical importance in the virus ' life cycle , has been posited as a novel target for anti - HIV drug development .
We report the synthesis and evaluation of triazole - containing compounds able to bind the FSS with high affinity and selectivity .