that certain RNA template structures and G - rich sequences , ahead of diverse reverse transcriptases can be strong stimulators for slippage at slippageprone template motif sequence 3 of such ' slippagestimulatory ' structures .
The retrotransposon - derived enzyme TGIRT exhibits more slippage in vitro than the retroviral enzymes
Here , we report that certain RNA template structures and G - rich sequences , ahead of diverse reverse transcriptases can be strong stimulators for slippage at slippageprone template motif sequence 3 of such ' slippagestimulatory ' structures .
The retrotransposon - derived enzyme TGIRT exhibits more slippage in vitro than the retroviral enzymes tested including that from HIV .