The dendritic cell specific C - type lectin DC - SIGN is involved in pathogen recognition through mannose and fucose
Many glycosylated viruses subvert this immune surveillance function
The dendritic cell specific C - type lectin DC - SIGN is involved in pathogen recognition through mannose and fucose containing carbohydrates leading to the induction of an anti - viral immune response .
Many glycosylated viruses subvert this immune surveillance function and exploit DC - SIGN as a port of entry and for trans - infection of target cells .