Porcine β - defensin 2 ( PBD-2 ) , <*> is a multifunctional cationic peptide with antimicrobial , immunomodulatory and growth - promoting abilities .
In this study , we aimed to generate marker - free pbd-2 knock - in pigs
Porcine β - defensin 2 ( PBD-2 ) , expressed by different tissues of pigs , is a multifunctional cationic peptide with antimicrobial , immunomodulatory and growth - promoting abilities .
In this study , we aimed to generate marker - free pbd-2 knock - in pigs using the CRISPR / Cas9 and Cre / loxP systems .