We generated several subtypes of attenuated recombinant influenza A viruses
We were able to demonstrate the potency of influenza virus NS vectors
We generated several subtypes of attenuated recombinant influenza A viruses expressing the 6-kDa early secretory antigenic target protein ( ESAT-6 ) of M. tuberculosis from the NS1 reading frame .
We were able to demonstrate the potency of influenza virus NS vectors to induce an M. tuberculosisspecific Th1 immune response in mice .