Misexpression of 3a in Drosophila caused a dominant rough eye phenotype .
that the 3a protein displayed a punctate cytoplasmic localization in Drosophila as in SARS - CoV - infected cells .
Misexpression of 3a in Drosophila caused a dominant rough eye phenotype .
Using a specific monoclonal antibody , we demonstrated that the 3a protein displayed a punctate cytoplasmic localization in Drosophila as in SARS - CoV - infected cells .