We report the design and synthesis of a series of dipeptide - type inhibitors with novel P3 scaffolds
A docking study <*> suggested the modification of a structurally flexible P3 N-(3methoxyphenyl)glycine with various rigid P3 moieties in 4 .
We report the design and synthesis of a series of dipeptide - type inhibitors with novel P3 scaffolds that display potent inhibitory activity against SARS - CoV 3CL pro .
A docking study involving binding between the dipeptidic lead compound 4 and 3CL pro suggested the modification of a structurally flexible P3 N-(3methoxyphenyl)glycine with various rigid P3 moieties in 4 .