Next - Generation Sequencing has been used in numerous investigations
Next - Generation Sequencing has also been employed
Next - Generation Sequencing has been used in numerous investigations to characterize andquantifythe genetic diversity of a virus sample through the mapping of polymorphisms and measurement of mutation frequencies .
Next - Generation Sequencing has also been employed to identify recombination events occurring within the genomes of higher organisms , for example , detecting alternative RNA splicing events and oncogenic chromosomal rearrangements .