Whether the transmissibility and pathogenicity of SARS - CoV-2 is actively evolving , and driven by adaptation to the new host and environments is still unknown .
Understanding the evolutionary mechanism <*> is essential for predicting the epidemic trend ,
Whether the transmissibility and pathogenicity of SARS - CoV-2 is actively evolving , and driven by adaptation to the new host and environments is still unknown .
Understanding the evolutionary mechanism underlying epidemiological and pathological characteristics of COVID-19 is essential for predicting the epidemic trend , and providing guidance for disease control and treatments .