A docking study <*> suggested the modification of a structurally flexible P3 N-(3methoxyphenyl)glycine with various rigid P3 moieties in 4 .
A SAR study around the P3 group in the lead 4 led to the identification of a rigid indole-2-carbonyl unit as one of the best P3 moieties ( 5c ) .
A docking study involving binding between the dipeptidic lead compound 4 and 3CL pro suggested the modification of a structurally flexible P3 N-(3methoxyphenyl)glycine with various rigid P3 moieties in 4 .
A SAR study around the P3 group in the lead 4 led to the identification of a rigid indole-2-carbonyl unit as one of the best P3 moieties ( 5c ) .