There are significant disparities in morbidity and mortality by sex , weight and diabetes status .
Numerous endocrine changes might drive these varied responses to SARS - CoV-2 infection
There are significant disparities in morbidity and mortality by sex , weight and diabetes status .
Numerous endocrine changes might drive these varied responses to SARS - CoV-2 infection including hormone and immune mediators , hyperglycemia , leukocyte responses , cytokine secretion , and tissue dysfunction .