The entry of two dengue virus ( DENV ) serotypes into Vero cells was analysed
By treatment with dansylcadaverine and chlorpromazine and overexpression of a dominant negative form of the Eps15 protein , a clathrin - mediated endocytosis for productive DENV-1 internalization into Vero cells was demonstrated
The entry of two dengue virus ( DENV ) serotypes into Vero cells was analysed using biochemical inhibitors , dominant negative mutants of cellular proteins involved in endocytic pathways , fluorescence microscopy and infectivity determinations .
By treatment with dansylcadaverine and chlorpromazine and overexpression of a dominant negative form of the Eps15 protein , a clathrin - mediated endocytosis for productive DENV-1 internalization into Vero cells was demonstrated whereas the infectious entry of DENV-2 in the same cell system was independent of clathrin .