The cell intrinsic innate immune responses provide a first line of defense against viral infection ,
In particular , many viruses manipulate cellular lipids
The cell intrinsic innate immune responses provide a first line of defense against viral infection , and often function by targeting cellular pathways usurped by the virus during infection .
In particular , many viruses manipulate cellular lipids to form complex structures required for viral replication , many of which are dependent on de novo fatty acid synthesis .