Porcine β - defensin 2 ( PBD-2 ) , <*> is a multifunctional cationic peptide with antimicrobial , immunomodulatory and growth - promoting abilities .
As the latest generation of genome - editing tool , CRISPR / Cas9 system makes it possible to enhance the expression of PBD-2 in pigs by site - specific knock - in of pbd-2 gene into the pig genome .
Porcine β - defensin 2 ( PBD-2 ) , expressed by different tissues of pigs , is a multifunctional cationic peptide with antimicrobial , immunomodulatory and growth - promoting abilities .
As the latest generation of genome - editing tool , CRISPR / Cas9 system makes it possible to enhance the expression of PBD-2 in pigs by site - specific knock - in of pbd-2 gene into the pig genome .