Chemical denaturant sensitivity of the dimeric main protease from severe acute respiratory syndrome ( SARS ) coronavirus to guanidinium chloride was examined in terms of fluorescence spectroscopy , circular dichroism , analytical ultracentrifuge , and enzyme activity change .
The various enzyme forms were characterized in terms of hydrophobicity and size - and - shape distributions .
Chemical denaturant sensitivity of the dimeric main protease from severe acute respiratory syndrome ( SARS ) coronavirus to guanidinium chloride was examined in terms of fluorescence spectroscopy , circular dichroism , analytical ultracentrifuge , and enzyme activity change .
The various enzyme forms were characterized in terms of hydrophobicity and size - and - shape distributions .