We found
that expression of the membrane anchored PLP domain from human HCoV - NL63 ( PLP2-TM ) or SARS - CoV ( PLpro - TM ) inhibits STING - mediated activation of IRF-3 nuclear translocation and induction of IRF-3 dependent promoters .
We found that expression of the membrane anchored PLP domain from human HCoV - NL63 ( PLP2-TM ) or SARS - CoV ( PLpro - TM ) inhibits STING - mediated activation of IRF-3 nuclear translocation and induction of IRF-3 dependent promoters .
We found that expression of the membrane anchored PLP domain from human HCoV - NL63 ( PLP2-TM ) or SARS - CoV ( PLpro - TM ) inhibits STING - mediated activation of IRF-3 nuclear translocation and induction of IRF-3 dependent promoters .