QuestionSBA
QuestionChoice
This is incorrect. Ageing results in an increase in body fat percentage and a decrease in lean muscle mass.
10004453
c
A change in drug distribution due to a decrease in body fat percentage and an increase in lean muscle mass
QuestionChoice
This is correct. In the elderly, there is a reduction in gastric pH and a reduction in intestinal blood flow which can decrease drug absorption.
10004451
a
Generalised decrease in drug absorption
QuestionChoice
This is incorrect. Ageing results in a reduction in liver blood flow.
10004454
d
Hepatic blood flow increases
QuestionChoice
This is incorrect. Ageing results in a decreased renal elimination of drugs.
10004452
b
Renal excretion unchanged
QuestionChoice
This is incorrect. Ageing results in a decrease in hepatic drug metabolism.
10004455
e
Intrinsic hepatic drug metabolism increases
Concept
Chapter
2693
4291
Pharmacokinetics with ageing
Topic
216
Ageing
13437
What changes are observed in pharmacokinetics with increased age?
a