QuestionSBA
QuestionChoice
Grapefruit is a CYP450 inhibitor, and, therefore, it inhibits the breakdown of warfarin and makes patients more susceptible to bleeds
10026981
a
Increased consumption of grapefruit
QuestionChoice
Spinach is rich in vitamin K and consumption should be limited as it may counteract the actions of warfarin making it less effective and patients susceptible to blood clots
10026984
d
Increased consumption of spinach
QuestionChoice
Oranges/orange juice is a safe alternative to grapefruit if taking warfarin
10026982
b
Increased consumption of oranges
QuestionChoice
Tomatoes are low in vitamin K and do not inhibit CYP450 enzymes. They are safe to consume whilst taking warfarin
10026985
e
Increased consumption of tomatoes
QuestionChoice
Kale is rich in vitamin K and consumption should be limited as it may counteract the actions of warfarin making it less effective and patients susceptible to blood clots
10026983
c
Increased consumption of kale
Concept
Chapter
2693
5944
CYP450 enzymes
Topic
195
Pharmacology
17794
A 65-year-old man presents to A&E with a nosebleed that "just won't stop". It has been bleeding for 30 minutes. Three years ago, he underwent surgery to replace his aortic valve and has been taking warfarin regularly since.

When visiting his GP earlier this week, he was diagnosed with hypertension and has been actively making changes to his lifestyle to become healthier.

What is the most likely cause of his prolonged nosebleed?
a