QuestionSBA
QuestionChoice
Although naloxone is the correct treatment for opioid toxicity, it is given IV, IM or via intranasal administration.
10035868
b
Oral naloxone
QuestionChoice
This is the reversal agent for ethylene glycol toxicity rather than opioid overdose. Opioid overdose is suggested here by low GCS, low RR and pinpoint pupils.
10035870
d
Fomepizil
QuestionChoice
This is the reversal agent for benzodiazepine toxicity. Although benzodiazepine toxicity also would present with a reduced GCS, dilated pupils are more likely than pinpoint pupils. Additionally, flumazenil is only licensed for reversal in anaesthesia or ICU, rather than overdoses in the community.
10035869
c
IV flumazenil
QuestionChoice
This is a likely case of opioid toxicity; suggested by the low respiratory rate, pinpoint pupils and low GCS. The correct treatment for opioid toxicity is naloxone. This is given IV, IM or via intranasal administration.
10035867
a
IV naloxone
QuestionChoice
This is used for paracetamol overdose rather than opioid overdose. Paracetamol toxicity would instead likely present with nausea, vomiting, headache and jaundice (in some severe or cases of delayed presentation).
10035871
e
N-acetyl cysteine
Concept
Chapter
2693
6161
Opioid toxicity
Topic
199
Emergency Medicine
19577
Opioid toxicity presents with respiratory depression, pinpoint pupils, and altered consciousness; naloxone is the antidote of choice.
A 25-year-old male is found collapsed. The only collateral history was provided by a passerby who found the patient was unresponsive and called an ambulance.

On assessment:

* A: No obvious angioedema, trachea central. Patient groaning occasionally
* B: Equal but slow chest expansion, no added sounds. RR 6, SpO2 91% on room air
* C: Regular pulse with warm peripheries. HS I + II + 0. HR 112, BP 108/60, Temperature 37.3 degrees, Urine Output unknown.
* D: GCS 7/15. Pinpoint pupils. Glucose within normal limits.
* E: No obvious rashes. Abdomen soft and non-tender

Which of the following is the most appropriate medication to prescribe?
a