QuestionSBA
QuestionChoice
p53 damage/loss will cause a loss of function mutation leading to damaged DNA and genome instability. This will result in an increased rate of mutation.
10005029
d
Genome stability
QuestionChoice
p53 damage/loss will cause unrestrained replication of damaged DNA which will further result in genome instability and cause resistance to apoptosis as a result of mutation accumulation.
10005026
a
Unrestrained replication of damaged DNA
QuestionChoice
This statement describes what would occur if p53 were functional.
10005027
b
Prevents the continuation of the cell into the S phase, giving time for DNA repair
QuestionChoice
This statement describes what would occur if p53 were functional.
10005028
c
p53 induces the cell to kill itself by apoptosis if the DNA damage is too severe
QuestionChoice
p53 will cause sustained proliferative signalling leading to an increased rate of mutation if it is damaged/mutated.
10005030
e
Unsustained proliferative signalling
Concept
Chapter
2693
4361
Cell cycle
Topic
181
Structure and Function of Cells
13552
There are many proteins located within the cell cycle at specific checkpoints.

Which of the following will occur if there is a damaged/non-functional p53 protein?
a