QuestionSBA
QuestionChoice
The degeneration of the corticospinal tract and alpha motor neurons is the pathophysiological process underlying amyotrophic lateral sclerosis, the commonest form of motor neurone disease.
10027045
e
Alpha motor neurons
QuestionChoice
Deposition of intracellular tau protein and extracellular amyloid beta plaques leads to the degeneration of hippocampal neurons in Alzheimer’s disease. This neuronal loss then spreads to other brain areas.
10027043
c
Hippocampal neurons
QuestionChoice
Loss of cholinergic and GABAergic neurons in the striatum is the pathophysiological process underlying Huntington’s disease. This occurs due to the expansion of trinucleotide repeats in the Huntingtin gene.
10027044
d
Cholinergic and GABAergic neurons in the striatum
QuestionChoice
Inflammation leading to the loss of oligodendrocytes in the central nervous system is the pathophysiological process underlying multiple sclerosis.
10027042
b
Oligodendrocytes
QuestionChoice
Degeneration of dopaminergic neurons in the substantia nigra is the pathophysiological process underlying Parkinson’s disease.
10027041
a
Dopaminergic neurons of the substantia nigra
Concept
Chapter
2693
3747
Parkinson's Disease
Topic
141
Neurology
17806
The neurodegenerative condition Parkinson’s disease is associated with the loss of which cell type?
a