QuestionSBA
QuestionChoice
ARBs, such as losartan, work by binding to the angiotensin II receptor, preventing endogenous angiotensin II from binding to them. This results in vasodilation which reduces blood pressure. Ramipril is an ACE inhibitor, not an angiotensin receptor blocker.
10023606
b
Angiotensin receptor blocker (ARB)
QuestionChoice
Beta-blockers, such as propranolol, work by blocking beta-2 adrenoreceptors in blood vessels. This results in less cAMP formation, which leads to vasodilation. Ramipril is an ACE inhibitor, not a beta blocker.
10023609
e
Beta-blocker
QuestionChoice
Ramipril is an ACE inhibitor, therefore it inhibits the formation of angiotensin-II. It also increases bradykinin levels in the blood, causing vasodilation which leads to reduced blood pressure.
10023605
a
ACE inhibitor
QuestionChoice
Thiazide-like diuretics, such as indapamide, work by inhibiting sodium reabsorption, and by extension, decreasing fluid reabsorption via osmotic gradients. This, in turn, reduces blood pressure. Ramipril is an ACE inhibitor, not a thiazide-like diuretic.
10023608
d
Thiazide-like diuretic
QuestionChoice
CCBs, such as amlodipine, work by blocking voltage-dependent L-type calcium channels, therefore inhibiting the influx of calcium and causing smooth muscle relaxation and vasodilation. This decreases blood pressure. Ramipril is an ACE inhibitor, not a calcium channel blocker.
10023607
c
Calcium channel blocker (CCB)
Concept
Chapter
2693
4215
ACE inhibitors
Topic
169
Cardiovascular pharmacology
17119
A 56-year-old male presents to the GP for his annual check-up. The GP records his blood pressure as 153/102mmHg and decides to prescribe him ramipril to help control his blood pressure.

What is the mechanism of action of this drug?
a