QuestionSBA
QuestionChoice
This does not fit with the clinical picture described. Stress fractures often occur after low-grade repetitive stress to a joint. Anaemia and hypercalcaemia are not typically seen.
10007553
c
Stress fracture
QuestionChoice
Sarcoidosis would present differently from the clinical picture described. Acute sarcoidosis presents with fever, joint pains, erythema nodosum, and bilateral hilar lymphadenopathy. Chronic sarcoidosis is characterised by pulmonary symptoms such as a dry cough, dyspnoea, reduced exercise tolerance, and crepitations on examination.
10007554
d
Sarcoidosis
QuestionChoice
Osteosarcoma is a type of bone cancer typically found in children or young adults. X-ray would commonly find a 'sunburst' pattern.
10007552
b
Osteosarcoma
QuestionChoice
This is a typical presentation of multiple myeloma. The clinical features can be remembered with the mnemonic CRABI: hypercalcemia, renal impairment, anaemia, bone pathology, and infections.
10007551
a
Multiple myeloma
QuestionChoice
Acute myeloid leukaemia (AML) can present with some similar features to multiple myeloma, for example, symptoms of bone marrow failure like anaemia and frequent infections. However, AML commonly involves examination findings such as hepatomegaly, splenomegaly or gum hypertrophy. By contrast, hypercalcaemia and back pain point towards a diagnosis of multiple myeloma.
10007555
e
Acute myeloid leukaemia
Concept
Chapter
2693
3923
myeloma
Topic
157
Haematology
14057
An 81-year-old female presents to the emergency department with severe back pain. On further investigation, you discover she has normocytic anaemia, raised serum creatinine, and a high calcium level. X-ray shows a fracture of the left femur.

Which of the following is the most likely diagnosis?
a