QuestionSBA
QuestionChoice
Constriction of the afferent arteriole would reduce the eGFR as less blood reaches the kidney. NSAIDs reduce the eGFR by constricting the afferent arteriole. ACEis reduce the eGFR by dilating the efferent arteriole. Both of these mechanisms reduce the filtration pressure in the Bowman's capsule, thus reducing the eGFR.
10001643
b
Increase eGFR, occurring due to constriction of the afferent arteriole
QuestionChoice
Dilation of the efferent arteriole would reduce the eGFR. This is the mechanism whereby ACEis reduce eGFR rather than NSAIDs. NSAIDs reduce the eGFR by constricting the afferent arteriole. ACEis reduce the eGFR by dilating the efferent arteriole. Both of these mechanisms reduce the filtration pressure in the Bowman's capsule, thus reducing the eGFR.
10001644
c
Reduce eGFR, occurring due to dilation of the efferent arteriole
QuestionChoice
Constricting the efferent arteriole would increase the eGFR due to an increase in the filtration pressure in the glomerulus. NSAIDs reduce the eGFR by constricting the afferent arteriole. ACEis reduce the eGFR by dilating the efferent arteriole. Both of these mechanisms reduce the filtration pressure in the Bowman's capsule, thus reducing the eGFR.
10001645
d
Increase eGFR, occurring due to constriction of the efferent arteriole
QuestionChoice
NSAIDs reduce the eGFR by constricting the afferent arteriole. ACEis reduce the eGFR by dilating the efferent arteriole. Both of these mechanisms reduce the filtration pressure in the Bowman's capsule, thus reducing the eGFR.
10001642
a
Reduce eGFR, occurring due to constriction of the afferent arteriole
QuestionChoice
NSAIDs reduce the eGFR by constricting the afferent arteriole. ACEI reduce the eGFR by dilating the efferent arteriole. Both of these mechanisms reduce the filtration pressure in the Bowman's capsule, thus reducing the eGFR.
10001646
e
No change
Concept
Chapter
2693
3954
Glomerular filtration rate
Topic
168
Renal Physiology
12875
What is the effect of NSAIDs on GFR and what is the underlying mechanism?
a