QuestionSBA
QuestionChoice
This is incorrect. Guanylate cyclase (also known as guanyl cyclase and guanylyl cyclase) is responsible for the conversion of GTP to cGMP.
10026016
b
Guanylate cyclase
QuestionChoice
This is incorrect. Phospholipase C is responsible for the hydrolysis of inositol phospholipids into inositol triphosphate (IP3) and diacylglycerol (DAG).
10026018
d
Phospholipase C
QuestionChoice
This is correct. There are 6 classes of adenylate cyclase (also known as adenyl cyclase and adenylyl cyclase) enzymes, all of which are responsible for catalysing the conversion of ATP to cAMP + diphosphate.
10026015
a
Adenylate cyclase
QuestionChoice
This is incorrect. Phosphodiesterase catalyses the reaction that converts cAMP to AMP
10026017
c
Phosphodiesterase
QuestionChoice
This is incorrect. Acetylcholinesterase (AChE) is responsible for the hydrolysis of acetylcholine into acetic acid and choline.
10026019
e
Acetylcholinesterase
Concept
Chapter
2693
4561
G protein-coupled receptors
Topic
166
General pharmacological concepts
17601
A 34 year old woman with chronic obesity is prescribed a new medication by the weight management clinic. This acts on a G-protein coupled receptor (GPCR).

Activation of the GPCR leads to an increase in the intracellular concentration of cyclic AMP (cAMP). This is achieved by the conversion of ATP to cAMP by an enzyme.

Which enzyme is responsible for the conversion of ATP to cAMP?
a