QuestionSBA
QuestionChoice
Patients who are taking isotretinoin require their hepatic function and serum lipids to be measured before starting treatment, one month after starting treatment and then on a three monthly basis.
50336
c
That he will require serum lipid monitoring every 6 months
QuestionChoice
Patients who are taking isotretinoin require their hepatic function and serum lipids to be measured before starting treatment, one month after starting treatment and then on a three monthly basis.
50338
e
That he will require annual visual acuity monitoring
QuestionChoice
Dizziness is listed as a rare/very rare side effect of isotretinoin so he is unlikely to experience this.
50335
b
That he will likely experience dizziness when taking isotretinoin
QuestionChoice
Isotretinoin has been linked to increased risk of depression and suicide therefore it is very important that the patient is informed to report any changes in their behaviour or mood after starting isotretinoin.
50334
a
To report any changes in his mood or behaviour
QuestionChoice
Nausea is listed as a rare/very rare side effect of isotretinoin so he is unlikely to experience this.
50337
d
That he will likely experience nausea when taking isotretinoin
Concept
Chapter
Osteoporosis, otherwise known as thin bones, is a condition associated with high risk of low trauma fractures due to reduced bone mineral density. Osteoclast activity exceeds osteoblast activity, meaning that bone resorption is occurring at a greater rate than bone formation.

**Symptoms and Signs**

- Generally asymptomatic until a fragility fracture occurs
- Back pain
- Kyphosis (stooped posture)
- Fragility fractures

**Risk factors**

- Female sex
- Increasing age
- Smoking
- Corticosteroid use
- Low BMI (< 20-25kg/m<sup>2</sup>)
- Low body weight (<58kg)
- Vitamin D deficiency

**Protective factors**

- Higher BMI
- Exercise - mechanical loading stimulates bone formation

**Diagnosis**
Osteoporosis can be detected on dual-energy x-ray absorptiometry (DEXA) scan.
A T score of < -2.5 indicates osteoporosis

**Management**

- Fall prevention
- Vitamin D and calcium supplementation
- Hormone replacement therapy (postmenopausal women)
- Oral bisphosphonates
2657
3650
Isotretinoin treatment increases the risk of low mood.
Topic
91
Paediatrics
10121
Case presentation: A 19-year-old man attends the dermatology clinic for his acne vulgaris medication. He has been taking tetracycline as instructed however his condition is not improving.



**PH**
Acne vulgaris

**DH**
Tetracycline 500mg PO BD

Due to his ongoing issues with his acne, his dermatologist commences him on isotretinoin.

Question: Select the most important information that should be provided for this patient.
a