QuestionSBA
QuestionChoice
This answer is incorrect. Canagliflozin is an example of an SGLT-2 inhibitor which works by increasing the excretion of glucose in the urine.
10007394
d
Canagliflozin
QuestionChoice
This answer is incorrect. Metformin is an example of a biguanide which inhibits hepatic gluconeogenesis and increases insulin sensitivity in the liver and muscles.
10007392
b
Metformin
QuestionChoice
This answer is incorrect. Sitagliptin is an example of a DPP-4 inhibitor, which works by increasing levels of GLP-1. GLP-1 stimulates insulin release and suppresses appetite.
10007393
c
Sitagliptin
QuestionChoice
This answer is incorrect. Pioglizatone is an example of a PPARG (peroxisome proliferator-activated receptor gamma) agonist which works by reducing insulin resistance and increasing glucose uptake into liver and muscle
10007395
e
Pioglitazone
QuestionChoice
This answer is correct. Gliclazide is an example of a sulphonylurea which binds to pancreatic beta cells to increase insulin secretion.
10007391
a
Gliclazide
Concept
Chapter
2693
4071
Anti-diabetic drugs mechanisms of action
Topic
133
Endocrinology
14025
A 67-year-old man with type 2 diabetes is commenced on a new anti-diabetic medication by his GP due to poor glucose control.

Which of the following anti-diabetic drugs work by increasing insulin secretion via binding to receptors on the surface of pancreatic beta cells?
a