QuestionSBA
QuestionChoice
Corticosteroid use is not associated with an increased risk of gout. Predisposing factors that increase the risk of gout typically act through one of two mechanisms: increased production of uric acid or reduced excretion of uric acid. Corticosteroid use does not cause either of these to occur.
10000460
e
Corticosteroid use
QuestionChoice
A vegetarian diet is not associated with an increased risk of gout. Red meat, on the other hand, is rich in purines and so results in elevated uric acid levels, thereby increasing the risk of gout.
10000459
d
Vegetarian diet
QuestionChoice
Hypouricaemia is decreased presence of uric acid within the blood and therefore reduces the risk of gout.
10000457
b
Hypouricaemia
QuestionChoice
This patient has presented with an acute episode of gout. Gout occurs due to the accumulation of urate crystals within joints, causing acute crystal arthropathies. Gout presents with severe pain and most commonly affects the 1st metatarsophalangeal joint but affects other joints such as the knee, ankle, and wrist. Diuretics cause reduced excretion of uric acid and are therefore an important predisposing factor to the development of gout.
10000456
a
Diuretic use
QuestionChoice
Non-Steroidal Anti-Inflammatory drugs (NSAIDs) do not increase the risk of gout. The BNF does not state gout as a recognized side-effect of NSAID use. Indeed, NSAIDs are actually used in the management of acute gout.
10000458
c
Non-Steroidal Anti-Inflammatory drugs
Concept
Chapter
2693
3768
Gout
Topic
146
Rheumatology
12638
A 67-year-old male presents to the emergency department with a 10-hour history of excruciating pain in his big toe. The pain began in the morning and has worsened in intensity throughout the day. He is unable to walk on the affected foot due to the pain. On examination, you identify that the patient's left 1st metatarsophalangeal joint is erythematous and swollen.

Which of the following is a predisposing factor to this patient's condition?
a