QuestionSBA
QuestionChoice
DNP causes the mitochondrial membrane to become leakier. This means fewer protons pass through H+/ATPase and therefore leads to a reduced production of ATP. The energy generated by the electrochemical gradient results in a release of heat and hyperthermia. Oxygen uptake is increased as a result of increased cell metabolism.
10026876
a
Reduced ATP production with increased oxygen uptake and increased heat production
QuestionChoice
DNP reduces the number of protons passing through ATPase and therefore reduces ATP production. Energy is released as heat instead resulting in hyperthermia. Oxygen uptake increases as a result of increased cell metabolism.
10026877
b
No change in ATP production with increased oxygen uptake and increased heat production
QuestionChoice
DNP reduces the number of protons passing through ATPase and therefore reduces ATP production. Energy is released as heat instead resulting in hyperthermia. Oxygen uptake increases as a result of increased cell metabolism.
10026880
e
Increased ATP production with increased oxygen uptake and decreased heat production
QuestionChoice
DNP reduces the number of protons passing through ATPase and therefore reduces ATP production. Energy is released as heat instead resulting in hyperthermia. Oxygen uptake increases as a result of increased cell metabolism.
10026879
d
Reduced ATP production with increased oxygen uptake and decreased heat production
QuestionChoice
DNP reduces the number of protons passing through ATPase and therefore reduces ATP production. Energy is released as heat instead resulting in hyperthermia. Oxygen uptake increases as a result of increased cell metabolism.
10026878
c
Increased ATP production with decreased oxygen uptake and increased heat production
Concept
Chapter
2693
5930
Electron transport chain
Topic
309
Biochemistry, cell biology and clinical chemistry
17773
2,4-Dinitrophenol (DNP) is an illegal drug that can be used for weight loss. It makes the mitochondrial membrane more permeable to protons.

Which of the following describes the effects of 2,4-DNP on ATP production?
a