QuestionSBA
QuestionChoice
This is incorrect. Salbutamol is a short-acting β2-adrenoreceptor agonist used in acute asthma management. Its duration of action is up to around four hours. By contrast, long-acting β2-adrenoreceptor agonists such as salmeterol are effective for up to 12 hours.
10025916
b
It is effective for up to 12 hours by inhalation
QuestionChoice
This is correct. Salbutamol is a short-acting β2-adrenoreceptor agonist used in acute asthma management. It binds selectively and reversibly to receptors of the respiratory tract. This inhibits the contraction of bronchial smooth muscle, resulting in bronchodilation.
10025915
a
It acts by relaxing bronchial smooth muscle
QuestionChoice
This is incorrect.  Salbutamol is a short-acting β2-adrenoreceptor agonist used in acute asthma management. It has little to no action on the β1 adrenoreceptors of the heart.
10025917
c
They have a high affinity for the β1 adrenoreceptors of the heart
QuestionChoice
This is incorrect.  Salbutamol is a short-acting β2-adrenoreceptor agonist used in acute asthma management. It is not an antagonist. Antagonism of these receptors would prevent bronchodilation, exacerbating the bronchoconstriction seen in asthma.
10025918
d
It belongs to the β2-adrenoreceptor antagonist class of drugs
QuestionChoice
This is incorrect. Salbutamol is a short-acting β2-adrenoreceptor agonist used in acute asthma management. It is used as reliever therapy when required. If it is required more than three times a week then the patient is said to have uncontrolled asthma and should be offered a regular 'preventer' inhaler.
10025919
e
They should be used once a day for well controlled asthma
Concept
Chapter
2693
4225
Salbutamol
Topic
189
Respiratory Pharmacology
17581
A 14-year-old teenage boy presents to their GP with shortness of breath and a cough that is worse at night. His only medical history is allergic rhinitis and eczema.

Spirometry shows an obstructive pattern of lung disease and positive reversibility testing. He is prescribed a salbutamol inhaler.

Which of the following is true of a salbutamol inhaler?
a