QuestionSBA
QuestionChoice
The patient is reporting regular bleeds with her last one occurring 5 days ago. There still is a minuscule chance she may be pregnant and one may choose to perform a urine pregnancy test before administering ulipristal acetate, but this is not strictly necessary
34409
e
Urine pregnancy test
QuestionChoice
There are generally no monitoring requirements prior to administering ulipristal acetate as emergency contraception
34405
a
No routine monitoring is required
QuestionChoice
Hyper/hypotension is not a known adverse effect of this drug
34406
b
Blood pressure
QuestionChoice
It is not necessary to measure height and weight prior to administering ulipristal acetate
34408
d
Height and weight
QuestionChoice
Ulipristal acetate is metabolised by the liver and as such liver function tests are recommended when it is being used long-term to treat fibroids. This is not necessary if it is taken as a single dose for emergency contraception
34407
c
Liver function tests
QuestionComment
BNF:
Perform liver function tests before treatment initiation—do not initiate if serum transaminases exceed 2 times the upper limit of normal. During the first 2 treatment courses, monitor liver function monthly; for further treatment courses, perform liver function tests once before each new treatment course and when clinically indicated. At the end of each treatment course, perform liver function tests after 2-4 weeks. Discontinue treatment if serum transaminases exceed 3 times the upper limit of normal and closely monitor patient.

Periodically monitor the endometrium following repeated intermittent treatment.
8324
QuestionComment
if you read above that it says "When used for uterine fibroids" 
8367
User
subscriber
Cystic Prognosis
User
subscriber
DNA Hypertension
QuestionComment
whatever you say im still doing the pregnancy test irl
61348
User
subscriber
Vaccine Complement
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

2618
2824
Ulipristal acetate side effects
Topic
76
Obstetrics and Gynaecology
6892
Case Presentation: A 27 year old woman attends the walk-in GUM clinic requesting emergency contraception. She had forgotten to take her combined contraceptive pill for two days in a row at the start of the week and had unprotected sex in the same period.


Her LMP was 5 days ago and she has a regular cycle of 28 days. She has never been pregnant before.

After counselling, it is agreed that she should take ulipristal acetate 30mg PO as a one-off dose for emergency contraception.

Question: Select the most appropriate monitoring option required before administering ulipristal acetate.
a