QuestionSBA
QuestionChoice
Somatic hypermutation in lymph nodes adds further diversity to the already rearranged VDJ segments. The enzyme AID does this by introducing point mutations to the variable region of the antibody.
10000941
a
Somatic hypermutation
QuestionChoice
This process happens by B cells to produce more antibodies with an increased affinity to a specific antigen.
10000943
c
Affinity maturation
QuestionChoice
When B cells have antibodies that are complementary to antigens, they will undergo clonal expansion, which makes more copies of that B cell and antibody.
10000945
e
Clonal expansion
QuestionChoice
This is the initial process at a genetic level that gives rise to antibody diversity. The immunoglobulin protein is yet to be made at this point.
10000942
b
Somatic recombination
QuestionChoice
This process generates the different isotypes of antibodies (eg IgG, IgA, IgE). It happens by changing the constant region of an antibody.
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d
Class switch recombination
Concept
Chapter
2693
3854
Antibodies
Topic
158
Immunology
12735
Once an antibody has been made from its genetic sequence, which process introduces further diversity?
a