QuestionSBA
QuestionChoice
Acute liver failure is characterised by coagulopathy (INR> 1.5) and altered levels of consciousness due to hepatic encephalopathy. Acute liver injury is the initial trigger due to a primary liver aetiology and therefore does not present with encephalopathy.
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a
Acute liver failure results in hepatic encephalopathy whilst acute liver injury does not
QuestionChoice
The most common cause of drug-induced liver injury and failure is paracetamol.
10024463
d
The most common cause of drug-induced acute liver injury and failure is amiodarone
QuestionChoice
Acute liver injury and acute liver failure **both** cause an increase in hepatocellular (AST, ALT) and cholestatic (ALP, GGT) enzymes.
10024461
b
Acute liver injury results in increased ALT and AST but normal ALP whilst acute liver failure has raised AST, ALT and ALP
QuestionChoice
Coagulopathy indicated by an INR >1.5 is a characteristic feature of acute liver failure and can also occur in acute liver injury.
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c
Coagulopathy does not occur in acute liver failure but occurs in acute liver injury
QuestionChoice
Patients should be treated with N-acetyl cysteine if ingestion of paracetamol is over 8 hours.
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e
Patients should be treated with activated charcoal if ingestion of paracetamol is over 8 hours
Concept
Chapter
2693
3986
Liver Failure
Topic
136
Gastroenterology
17290
Which of the following statements on acute liver failure and acute liver injury is correct?
a