QuestionSBA
QuestionChoice
Crohn's disease is associated with an increase in goblet cells, as opposed to a decrease.
10002410
d
Loss of goblet cells
QuestionChoice
Based on the symptoms and initial investigations, this patient likely has Crohn's disease. The presence of mouth ulcers and skip lesions on colonoscopy lean more towards Crohn's disease, as opposed to ulcerative colitis. Some of the key histological changes in Crohn's disease include granulomas, goblet cells, and inflammation in all layers from the mucosa to the serosa.
10002407
a
Granulomas
QuestionChoice
In Crohn's disease, inflammation can affect any layer of the gastrointestinal tract, from the mucosa to the serosa.
10002409
c
No inflammation beyond the submucosal layer
QuestionChoice
Crypt abscesses are classically seen in patients with ulcerative colitis, as opposed to Crohn's disease.
10002411
e
Crypt abscesses
QuestionChoice
Pseudopolyps are classically seen in patients with ulcerative colitis, as opposed to Crohn's disease.
10002408
b
Pseudopolyps
Concept
Chapter
2693
4000
Crohn's disease
Topic
136
Gastroenterology
13028
A 28-year-old male presents with frequent diarrhoea, lethargy, and recurrent mouth ulcers. His symptoms started a few months ago, and are occasionally accompanied by abdominal pain. After initial investigations, a colonoscopy is performed, which reveals inflammatory changes with skip lesions. A colonic biopsy is also taken.

Which of the following features is most likely to be seen on histology?
a