QuestionSBA
QuestionChoice
Caspases 2, 8, and all 9 are 'initiator' caspases. Initiators begin the process of apoptosis, particularly by converting pro-executioner caspases into active executioner caspases. However they do not directly carry out proteolysis themselves.
10007047
b
Caspase 2, 8, 9
QuestionChoice
Caspase 3 is an 'executioner' but 8 and 9 are 'initiator' caspases.
10007048
c
Caspase 3, 8, 9
QuestionChoice
These are the executioner caspases, causing nuclear fragmentation, cytoskeletal disruption, membrane alterations and organelle reduction.
10007046
a
Caspase 3, 6 and 7
QuestionChoice
Caspase 6 is an 'executioner' but 7 and 8 are 'initiator' caspases.
10007049
d
Caspase 6, 7, 8
QuestionChoice
Caspase 3 is an 'executioner'. However caspases 1 and 5 are not directly involved in apoptosis.
10007050
e
Caspase 1, 3, 5
Concept
Chapter
2693
3886
Apoptosis
Topic
181
Structure and Function of Cells
13956
Caspases are enzymes that play a crucial role in programmed cell death (apoptosis). They include both 'initiators' that initiate the apoptosis signal and 'executioner' that carry out proteolysis.

Which of the following caspases are the 'executioner' caspases?
a