QuestionSBA
QuestionChoice
In an autosomal recessive pedigree you usually cannot follow the disease throughout the pedigree. You see horizontal transmission (siblings affected) and an equal incidence of males and females affected. Note that there may be evidence of consanguinity.
10005037
b
Autosomal recessive inheritance
QuestionChoice
This is usually shown on a pedigree by a double line drawn between two people. This suggests that two people are 'related by blood' and therefore, have a common ancestor.
10005040
e
Consanguinity
QuestionChoice
Maternal inheritance on a pedigree would show all offspring to be affected as the mothers pass on mitochondria from their egg. The sperm's mitochondria are actively expelled from the fertilised egg and therefore not passed on to offspring.
10005038
c
Maternal inheritance
QuestionChoice
An X-linked dominant pedigree will appear similar to an autosomal dominant pedigree. However, there will be an excess of affected females and no male-to-male transmission.
10005039
d
X-linked dominant disease
QuestionChoice
This is correct. This is because within this pedigree you see affected people in each generation. Both males and females are affected but more importantly, all forms of transmission are seen including male-to-male transmission.
10005036
a
Autosomal dominant inheritance
Concept
Chapter
2693
4363
Pedigree chart
Topic
156
Medical Genetics
13554
Picture
1517
pedigree.png
images/4wr9djji1682081701181.jpg
images/4wr9djji1682081701181_256.jpg
images/4wr9djji1682081701181_512.jpg
OQgGBIC2iZdvmmaIeZgAAAAAAA==
Topic
156
Medical Genetics
Which type of inheritance can be seen in the following pedigree?

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a