QuestionSBA
QuestionChoice
This transporter is found on the basolateral membrane of epithelium within the distal convoluted tubule. Its role is to secret sodium ions into the extracellular fluid, to reduce intracellular sodium levels. This creates a sodium gradient for sodium to move into the epithelial cells via the apical sodium/chloride co-transporter.
10025642
c
Sodium/Potassium ATPase co-transporter
QuestionChoice
This active transporter is crucial in creating an osmotic gradient between the urine in the loop of Henle and the blood surrounding it. It draws water out of the urine and increases the concentration of the urine that passes into the collecting ducts of the nephron.
10025640
a
Sodium/Potassium/2-Chloride cotransporter
QuestionChoice
These are found in the proximal convoluted tubule apical epithelium. Sodium ions move down a concentration gradient into the epithelial cells. These sodium ions are co-transported alongside other solutes such as amino acids, enabling the movement of these solutes against their concentration gradient.
10025644
e
Sodium-amino acid linked transporters
QuestionChoice
These are found in the proximal convoluted tubule apical epithelium. Sodium ions move along their own concentration gradient into the epithelial cells. These sodium ions are co-transported alongside other solutes such as glucose, enabling the movement of these other solutes against their concentration gradient.
10025643
d
Sodium-glucose linked transporters
QuestionChoice
This is found on the apical membrane of epithelial cells of the distal convoluted tubule. It acts to transport sodium and chloride into the cell following a sodium gradient.
10025641
b
Sodium/chloride cotransporter
Concept
Chapter
2693
4242
Salt Transport in the loop of Henle
Topic
168
Renal Physiology
17526
A 72 year old man is seen by his GP. He has developed bilateral pitting oedema across both ankles, which is making it uncomfortable to walk long distances. The GP suggests trialling a loop diuretic.

Which of the following transporter acts within the thick limb of the loop of Henle?
a