QuestionSBA
QuestionChoice
This is the correct choice of antibiotic, dose and duration for uncomplicated lower UTI without visible haematuria in pregnancy, in accordance to NICE Guidelines.
10028492
a
Nitrofurantoin MR 100mg BD for 7 days
QuestionChoice
Trimethoprim should be avoided in the first trimester of pregnancy as it is a folate antagonist and so would be teratogenic (increasing risk of neural tube defects).
10028496
e
Trimethoprim 200mg BD 3 days
QuestionChoice
Cefelexin is a 2nd line antibiotic for lower UTIs in pregnancy.
10028495
d
Cefelexin 500mg for 7 days
QuestionChoice
This is the correct choice of antibiotic and dose, however the duration should be 7 days. 3 day courses are reserved for uncomplicated lower UTIs outside of pregnancy.
10028493
b
Nitrofurantoin MR 100mg BD for 3 days
QuestionChoice
NICE recommend amoxicillin only in the presence of culture results and proven sensitivity. This patient is also allergic to penicillin and so it would not be appropriate regardless.
10028494
c
Amoxicillin 500mg TDS for 7 days
Concept
Chapter
2693
6073
UTI in Pregnancy
Topic
322
Medicine
18098
Case Presentation: A 31-year-old female attends the GP complaining of pain on urination and urinating more frequently. She is 12 weeks pregnant, and the pregnancy has been uncomplicated so far. She is afebrile and there is no visible haematuria. **PH** Nil **DH** Nil Allergy to penicillin.


**On examination**

Warm and well perfused, CRT 2s. Mild suprapubic tenderness on palpation.

Temperature 37.1°C, HR 84, RR 12, BP 115/78, O2 94% RA

**Investigations**

Urine dipstick: Nitrites ++, all other parameters negative.

Question: Select the most appropriate management at this stage.
a