QuestionSBA
QuestionChoice
Here, maturation and enlargement of chondrocytes prepare the matrix for calcification in the next zone.
10006513
c
Hypertrophic zone
QuestionChoice
Here, osteoblasts and vessels penetrate the empty spaces produced from the calcification zone and create new bone, whilst osteoclasts break down the calcified cartilaginous matrix.
10006515
e
Ossification zone
QuestionChoice
Here, there is no cellular proliferation. It instead acts as a site of matrix production and storage for lipids, glycogen, and proteoglycan.
10006512
b
Reserve zone
QuestionChoice
Here, calcification of the matrix causes chondrocytes to die as it restricts nutrient diffusion, producing empty spaces.
10006514
d
Calcification zone
QuestionChoice
Here, chondrocytes divide rapidly through mitosis and form columns within the matrix. This proliferation of chondrocytes pushes the diaphysis away from the epiphysis, leading to longitudinal growth.
10006511
a
Proliferative zone
Concept
Chapter
2693
4516
Cartilage and endochondral ossification
Topic
164
Physiology and pathology of bone
13849
The epiphyseal growth plate is a thin cartilage between the primary and secondary ossification centres produced in endochondral ossification.

Which zone of the growth plate is primarily responsible for growth?
a