QuestionSBA
QuestionChoice
Migraine is a headache disorder characterised by episodes of severe, unilateral, throbbing headaches associated with nausea, photophobia and phonophobia. It would not account for the palpitations or severe hypertension seen in this patient.
10004625
e
Migraine
QuestionChoice
This is the autoimmune destruction of the adrenal glands, reducing the production of cortisol and aldosterone. This would present with features such as lethargy, weakness, hypotension, hyperpigmentation, weight loss, nausea and vomiting.
10004622
b
Addison's disease
QuestionChoice
Although this may account for the tachycardia, sweating and palpitations the patient is experiencing, other features that may be seen in thyrotoxicosis include weight loss, restlessness and heat intolerance, depending on the cause. Thyrotoxicosis would not account for the dangerously high blood pressure measured in this patient.
10004624
d
Thyrotoxicosis
QuestionChoice
This is a rare catecholamine-secreting tumour that can be associated with other pathologies. The large amount of catecholamines (noradrenaline and adrenaline) secreted results in a really high blood pressure, as seen here. Other features associated with pheochromocytoma include headaches, palpitations, sweating and anxiety.
10004621
a
Phaeochromocytoma
QuestionChoice
This is the autoimmune destruction of the insulin-producing beta cells. The deficiency of insulin causes raised glucose levels. Although this often presents in childhood or early adult life, it involves features such as chronic weight loss, polydipsia and polyuria, or features of diabetic ketoacidosis (abdominal pain, vomiting, decreased consciousness).
10004623
c
Type 1 diabetes mellitus
Concept
Chapter
2693
4311
Phaeochromocytoma
Topic
133
Endocrinology
13471
A 26-year-old man presents with severe headaches that have been gradually worsening over the past 3 months and palpitations. On examination, he is tachycardic, sweating and has a blood pressure of 188/90mmHg.

Based on the clinical features described, which of the following is the most likely diagnosis?
a