QuestionSBA
QuestionChoice
This is the mechanism of action of ciprofloxacin, a quinolone antibiotic
10006063
c
Inhibits topoisomerase II (DNA gyrase) and topoisomerase IV (both Type II topoisomerases)
QuestionChoice
This is the mechanism of action of cephalexin, a cephalosporin
10006065
e
Inhibits bacterial cell wall peptidoglycan synthesis by inhibition of penicillin-sensitive enzymes (transpeptidases, carboxypeptidases)
QuestionChoice
This is the mechanism of action of digoxin, a drug that can be used in the treatment of hart failure
10006064
d
Inhibits the sodium/potassium-ATPase within the plasma membrane of cardiac myocyte
QuestionChoice
Aminoglycosides bind to the aminoacyl site of 16S ribosomal RNA within the 30S ribosomal subunit, leading to misreading of the genetic code and inhibition of translocation
10006061
a
Bind to the 16S ribosomal RNA so inhibit translocation
QuestionChoice
This is the mechanism of action of penicillin
10006062
b
Bind the beta-lactam ring to DD-transpeptidase, inhibiting its cross-linking activity and preventing new cell wall formation
Concept
Chapter
2693
4471
Aminoglycosides
Topic
223
Antibiotic pharmacology
13759
You're treating a 43 year old female patient and your consultant prescribes gentamicin. This is an aminoglycoside.

Which of the following best describes it's mechanism of action?
a