QuestionSBA
QuestionChoice
Used for volatile/gaseous anaesthetics and aerosols. This route can produce rapid adjustments in the plasma concentration of the drug. Drugs delivered via aerosol will often produce high local concentrations of drug without systemic effects
10026783
d
Inhalation
QuestionChoice
Subcutaneous injection will usually produce effects faster than oral administration but must be absorbed into circulation from the injection site. This can be limited by diffusion through tissue and removal by local blood flow.
10026784
e
Subcutaneous injection
QuestionChoice
Very little absorption of most drugs takes place until it reaches the small intestine. Around 75% of the drug will be absorbed in 1-3 hours. Factors affecting absorption include gut content, gut motility, blood flow and formulation.
10026781
b
Oral
QuestionChoice
This allows 100% of the active drug to be delivered into the systemic circulation and is not limited by diffusion or first-pass metabolism
10026780
a
Intravenous injection
QuestionChoice
Absorption following administration can be unreliable but can be more complete than oral/buccal administration as less of the capillary drainage returns to circulation via the portal vein
10026782
c
Rectal
Concept
Chapter
2693
5921
Bioavailability
Topic
195
Pharmacology
17754
Which of the following routes of administration has a bioavailability of 100%?
a