QuestionSBA
QuestionChoice
Vitamin K deficiency leads to a prolonged PT, due to the involvement of the extrinsic pathway of the clotting cascade.
10004855
e
Vitamin K deficiency
QuestionChoice
Haemophilia B is an inherited bleeding disorder caused by a deficiency of clotting factor IX. You would expect to see a prolonged APTT, with normal TT, PT and bleeding time.
10004853
c
Haemophilia B
QuestionChoice
Haemophilia A is an inherited bleeding disorder caused by a deficiency of clotting factor VIII. You would expect to see a prolonged APTT, with normal TT, PT and bleeding time.
10004852
b
Haemophilia A
QuestionChoice
Antiphospholipid syndrome is an acquired autoimmune disease which is characterised by a predisposition to venous and arterial thromboses. A key point to remember is that in antiphospholipid syndrome, there is an isolated prolongation of APTT!
10004854
d
Antiphospholipid syndrome
QuestionChoice
Von Willebrand disease is the most common inherited bleeding disorder, and thus should be learnt well for exams! Clotting tests reveal normal PT and TT, prolonged APTT (functional factor VIII deficiency) and bleeding time.
10004851
a
Von Willebrand disease
Concept
Chapter
2693
4340
Interpretation of blood results in bleeding disorders
Topic
157
Haematology
13517
A patient is referred to the haematology clinic after noticing they tend to bleed easily and their gums bleed excessively after brushing their teeth. They undergo a panel of clotting tests.

Their clotting tests reveal a normal PT and TT, and a prolonged APTT and bleeding time.

Which of the following is the most likely cause of their presentation?
a