QuestionSBA
QuestionChoice
This is incorrect, low BMI and low body weight are risk factors for osteoporosis rather than obesity.
10025858
d
High BMI is a risk factor
QuestionChoice
This is incorrect. There is a decrease in bone mineral density in osteoporosis, caused by osteoclast activity exceeding osteoblast activity. If there were higher osteoblast activity, we would expect an increase in bone bone mineral density rather than a reduction.
10025857
c
Osteoblast activity exceeds osteoclast activity
QuestionChoice
This is correct. Osteoclasts are responsible for bone resorption whilst osteoblasts are responsible for bone growth. These two cells usually work together to maintain healthy bones. However, in osteoporosis, osteoclast activity exceeds osteoblast activity, thus reducing bone mineral density. This increases an individual's risk of fractures as the less-dense bone fractures more easily.
10025855
a
Osteoclast activity exceeds osteoblast activity
QuestionChoice
This is incorrect. Osteoclasts and osteoblasts are responsible for bone resorption and bone remodelling respectively. In osteoporosis, the bone is less dense meaning it is being resorbed at a faster rate than it is being remodelled. Therefore, an increase in osteoclast activity compared to osteoblast is a factor in the development of osteoporosis.
10025859
e
Osteoporosis occurs independent of osteoclast and osteoblast activity
QuestionChoice
This is incorrect. There is a decrease in bone mineral density in osteoporosis which increases an individual's risk of fractures.
10025856
b
Increase in bone mineral density
Concept
Chapter
2693
4208
Osteoporosis
Topic
154
Musculoskeletal physiology and disease
17569
A 71 year old woman is reviewed by the bone health team following a hospital admission for a right neck of femur fracture. She undergoes a DEXA scan, which identifies osteoporosis.

Which of the following is a feature of osteoporosis?
a