QuestionSBA
QuestionChoice
This is incorrect. This is the mechanism of ticagrelor, an anti-platelet that can be used as part of secondary prevention for cardiovascular disease. Atorvastatin is a statin that reduces cholesterol by inhibiting HMG-CoA reductase; an enzyme involved in the liver's production of cholesterol.
10025944
e
P2Y12 receptor antagonist
QuestionChoice
This is correct. Atorvastatin is a type of statin, which can be given as primary prevention of cardiovascular disease when Qrisk score is raised (>10%). Statins reduce cholesterol by inhibiting HMG-CoA reductase; an enzyme involved in the liver's production of cholesterol.
10025940
a
Inhibition of HMG-CoA reductase
QuestionChoice
This is incorrect. ACE inhibitors such as ramipril are used as part of secondary prevention for cardiovascular disease. Atorvastatin is a statin that reduces cholesterol by inhibiting HMG-CoA reductase; an enzyme involved in the liver's production of cholesterol.
10025941
b
Inhibition of Angiotensin converting enzyme (ACE)
QuestionChoice
This is incorrect. Aldosterone antagonists are used as part of secondary prevention for cardiovascular disease if the patient has clinical heart failure. Atorvastatin is a statin that reduces cholesterol by inhibiting HMG-CoA reductase; an enzyme involved in the liver's production of cholesterol.
10025943
d
Antagonism of aldosterone
QuestionChoice
This is incorrect. Beta-blockers are used as part of secondary prevention for cardiovascular disease. Atorvastatin is a statin that reduces cholesterol by inhibiting HMG-CoA reductase; an enzyme involved in the liver's production of cholesterol.
10025942
c
Blockade of beta adrenergic receptors
Concept
Chapter
2693
4116
Statins
Topic
169
Cardiovascular pharmacology
17586
A 52 year old male attends his GP surgery for an annual medical review, as required for his profession as a lorry driver. He is found to have a Qrisk score of 15%. The GP recommends he commence atorvastatin to reduce his risk of having a major cardiovascular event.

Which of the following describes the mechanism of action of atorvastatin?
a