QuestionSBA
QuestionChoice
This is the mode of action of non-depolarising muscle relaxants, such as atracurium and vecuronium, which are competitive antagonists of the nicotinic receptor.
10027223
c
It competes with acetylcholine for the nicotinic receptor orthosteric binding site but does not activate the receptor
QuestionChoice
Depolarising agents are agonists of the nicotinic acetylcholine receptor. They bind to the orthosteric ligand binding site, causing receptor activation and cation influx into the motor end plate.
10027224
d
It binds to an allosteric site on the nicotinic acetylcholine receptor
QuestionChoice
Depolarising agents are agonists of the postsynaptic nicotinic acetylcholine receptor, causing receptor activation and cation influx into the motor end plate. They do not inhibit presynaptic acetylcholine release.
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e
It inhibits the presynaptic release of acetylcholine
QuestionChoice
Depolarising agents are agonists of the nicotinic acetylcholine receptor, causing receptor activation and cation influx into the motor end plate.
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a
It activates the nicotinic acetylcholine receptor, allowing cation influx
QuestionChoice
Suxamethonium is an agonist of the nicotinic acetylcholine receptor, like acetylcholine. As suxamethonium is not broken down by acetylcholinesterase, it produces a more prolonged depolarisation of the motor end plate but doesn’t have any inhibitory effect on the breakdown of acetylcholine itself.
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b
It inhibits the breakdown of acetylcholine
Concept
Chapter
2693
5965
Suxamethonium
Topic
172
Pharmacology of the Nervous System
17842
What is the mode of action of the depolarising agent suxamethonium?
a