QuestionPrescription
QuestionComment
Make spaces for drug names e.g. dalteparin sodium as 2 words (with a space) correct answers. 
6480
User
subscriber
Tachycardia Outpatient
QuestionComment
BNF just has it as dalteparin - should give marks for it pls
6924
User
subscriber
Jaundice Biopsy
QuestionComment
what about Fondaparinux?
61059
User
subscriber
Ortho bro
QuestionComment
Why not apixaban because in the BNF it is used post surgery for this specific surgery of the hip

61144
User
subscriber
Serotonin Fracture
QuestionComment
Surely enoxaparin 150mg/mL is correct too if its 40mg dose?
61521
User
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Claire
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

2618
2693
Post-Operative Thromboprophylaxis 
Topic
13
Neurosurgery
# Drug choice feedback

Apart from mechanical means, administration of a low-molecular weight heparin should be offered to all surgical patients in whom the risk of venous thromboembolism outweighs the risk of bleeding. In certain situations, such as in high-risk patients and/or those undergoing orthopaedic procedures, DOACs can also be given as prophylaxis, as per the BNF.

# Dose/Route/Frequency/Duration feedback

The correct dose depends on the individual low-molecular weight heparin offered. This can only be given subcutaneously and once-daily. It should be continued until mobility is no longer reduced (generally 5-7 days) and reviewed at discharge.
6757
PrescriptionAnswer
PrescribeAnswerData
3500 units
PrescribeAnswerData
tinzaparin sodium 10 000 units/mL injection
PrescribeAnswerData
Entire inpatient stay
PrescribeAnswerData
daily (OD)
PrescribeAnswerData
subcutaneous (SC)
PrescriptionAnswer
PrescribeAnswerData
2.5 mg
PrescribeAnswerData
apixaban 2.5 mg tablets
PrescribeAnswerData
Entire inpatient stay
PrescribeAnswerData
daily (OD)
PrescribeAnswerData
subcutaneous (SC)
PrescriptionAnswer
PrescribeAnswerData
2500 units
PrescribeAnswerData
dalteparin sodium 10 000 units/mL injection
PrescribeAnswerData
Entire inpatient stay
PrescribeAnswerData
daily (OD)
PrescribeAnswerData
subcutaneous (SC)
PrescriptionAnswer
PrescribeAnswerData
5000 units
PrescribeAnswerData
dalteparin sodium 10 000 units/mL injection
PrescribeAnswerData
Entire inpatient stay
PrescribeAnswerData
daily (OD)
PrescribeAnswerData
subcutaneous (SC)
PrescriptionAnswer
PrescribeAnswerData
40 mg
PrescribeAnswerData
enoxaparin sodium 100 mg/mL injection
PrescribeAnswerData
Entire inpatient stay
PrescribeAnswerData
daily (OD)
PrescribeAnswerData
subcutaneous (SC)
PrescriptionAnswer
PrescribeAnswerData
10 mg
PrescribeAnswerData
rivaroxaban 10 mg tablets
PrescribeAnswerData
Entire inpatient stay
PrescribeAnswerData
daily (OD)
PrescribeAnswerData
oral (PO)
Case Presentation: A 52-year-old woman has been admitted to the orthopaedic ward for observation after an elective hip replacement. 


## PH

Fibroids, hypertension, previous facial squamous cell carcinoma

## DH

Nifedipine (extended-release) 30mg PO OD

## On examination

Appears well and oriented to time and place. Bedbound - awaiting her first physiotherapy assessment. Anti-embolism stockings seen.

Temperature 36.3°C, HR 72, RR 13, BP 135/78, O2 98% RA, GCS 15, Weight 82kg

## Investigations

FBC: Hb 139, WCC 11.3, Plts 278

U&Es: Na<sup>+</sup> 142, K<sup>+</sup> 4.7, Cl<sup>-</sup> 105, Ur 7.2, Cr 69, eGFR >90mL/min/1.73m<sup>2</sup>

Clotting: normal

# Prescribing Request

Write a prescription for one drug that is most appropriate for prophylaxis of venous thromboembolism in this patient.