QuestionSBA
QuestionChoice
Alpha thalassemia involves the genes HBA1 and HBA2.  In alpha-thalassemia, there are less alpha chains, resulting in fewer normal hemoglobin molecules. Additionally, unstable beta globin molecules are produced which lead to increased red blood cell destruction.
10006191
a
Chromosome 16
QuestionChoice
Chromosome 15 is not involved in thalassaemia, this chromosome is involved in Prader-Willi syndrome
10006195
e
Chromosome 15
QuestionChoice
Chromosome 21 is not involved in thalassaemia, the presence of three 21 chromosomes leads to Down's syndrome, or trisomy 21
10006193
c
Chromosome 21
QuestionChoice
Beta-thalassemia, not alpha thalassaemia is caused by mutations in the beta globin gene on chromosome 11
10006192
b
Chromosome 11
QuestionChoice
The X chromosome is not involved in thalassaemia, the absence of an x chromosome e.g. 45XO leads to Turner's syndrome
10006194
d
X Chromosome
Concept
Chapter
2693
4484
Thalassaemia
Topic
157
Haematology
13785
What chromosome contains the mutation for alpha thalassaemia?
a