QuestionSBA
QuestionChoice
Salbutamol is a short-acting beta-2 agonist which is usually the first-line treatment for patients with asthma. It relaxes muscles of the airway leading to dilation and the reduction of breathlessness.
10004006
a
Stimulates bronchial smooth muscle Beta-2 receptors
QuestionChoice
This is the mechanism of action of inhaled corticosteroids such as beclomethasone which modify immune responses. These are usually prescribed second-line in addition to salbutamol in patients who remain symptomatic.
10004007
b
Binds to glucocorticoid receptors
QuestionChoice
These drugs are used for the treatment of chronic obstructive pulmonary disease (COPD) rather than asthma and include ipratropium (short-acting) and tiotropium (long-acting). They have a bronchodilatory effect.
10004010
e
Muscarinic Antagonist
QuestionChoice
Examples of this class of drugs include Montelukast. This is used in the management of chronic asthma and is prescribed after steroids and Beta-2 agonists have failed to control symptoms.
10004009
d
Leukotriene receptor antagonist
QuestionChoice
This is the mechanism of action of theophylline and aminophylline which are used in the treatment of severe asthma attacks and chronic persistent asthma. They have both an anti-inflammatory and bronchodilator effect.
10004008
c
Phosphodiesterase inhibition
Concept
Chapter
2693
4225
Salbutamol
Topic
189
Respiratory Pharmacology
13348
A 16-year-old girl presents to her GP complaining of a wheeze and shortness of breath during exercise. She is diagnosed with asthma and prescribed a salbutamol inhaler.

What is the mechanism of action of salbutamol in asthma?
a