QuestionSBA
QuestionChoice
Furosemide will increase the delivery of Na+ to the DCT, leading to a promotion of K+ loss, so patients taking Furosemide are at risk of hypokalaemia.
10009573
d
Furosemide decreases Na<sup>+</sup> delivery to the Distal Convoluted Tubule which will help to promote the retention of K<sup>+</sup> ions
QuestionChoice
Loop diuretics actually **block** sodium chloride’s entry into the Macula Densa causing the patient to have volume depletion. As a consequence, the Renin-Angiotensin-Aldosterone System will be activated to stimulate Na+ retention and K+ loss.
10009574
e
Loop diuretics like Furosemide stimulate NaCl entry into the Macula Densa, helping to increase a patient’s circulating volume and causing an activation of the renin-angiotensin-aldosterone (RAAS) system
QuestionChoice
Incorrect. Furosemide in fact blocks the Na<sup>+</sup>/2Cl<sup>-</sup>/K<sup>+</sup> symporter of the thick ascending limb of the Loop of Henlé
10009572
c
Furosemide works on the Na<sup>+</sup>/H<sup>+</sup> antiporter within the thick ascending limb of the Loop of Henlé
QuestionChoice
Correct Answer. This will create an osmotic gradient which will increase water loss from the kidneys.
10009570
a
Furosemide is a loop diuretic, which causes 15-25% of filtered sodium (Na<sup>+</sup>) to be excreted within the urine
QuestionChoice
The mechanism of action of Furosemide will **reduce** the ability of the loop of henlé to concentrate urine by preventing the creation of a hypertonic interstitium in the medulla
10009571
b
Furosemide increases the ability of the loop of Henlé to concentrate urine by creating a hypotonic interstitium in the medulla
Concept
Chapter
2693
5355
Diuretics - Loop Diuretics
Topic
263
Renal
14462
A patient has been prescribed the medication, Furosemide.

Which of the following statements is the correct regarding Furosemide?
a