QuestionSBA
QuestionChoice
This is incorrect. PPAR is a transcription factor involved in carbohydrate metabolism. The correct answer was HIF-2. In response to hypoxia, mesangial cells in the kidney are stimulated to release erythropoietin. This is regulated primarily by the transcription factor hypoxia-induced factor 2 (HIF-2). HIF-2 is degraded by iron and hence during hypoxia, when iron levels are low, the raised HIF-2 levels stimulate more erythropoietin release.
10026464
e
PPAR
QuestionChoice
This is incorrect. CREB is a transcription factor involved in cell proliferation and differentiation. The correct answer was HIF-2. In response to hypoxia, mesangial cells in the kidney are stimulated to release erythropoietin. This is regulated primarily by the transcription factor hypoxia-induced factor 2 (HIF-2). HIF-2 is degraded by iron and hence during hypoxia, when iron levels are low, the raised HIF-2 levels stimulate more erythropoietin release.
10026462
c
CREB
QuestionChoice
This is incorrect. PDX-1 is a transcription factor involved in glucose homeostasis. The correct answer was HIF-2. In response to hypoxia, mesangial cells in the kidney are stimulated to release erythropoietin. This is regulated primarily by the transcription factor hypoxia-induced factor 2 (HIF-2). HIF-2 is degraded by iron and hence during hypoxia, when iron levels are low, the raised HIF-2 levels stimulate more erythropoietin release.
10026461
b
PDX-1
QuestionChoice
This is correct. In response to hypoxia, mesangial cells in the kidney are stimulated to release erythropoietin. This is regulated primarily by the transcription factor hypoxia-induced factor 2 (HIF-2). HIF-2 is degraded by iron and hence during hypoxia, when iron levels are low, the raised HIF-2 levels stimulate more erythropoietin release.
10026460
a
HIF-2
QuestionChoice
This is incorrect. STAT3 is a transcription factor involved in cell proliferation and differentiation. The correct answer was HIF-2. In response to hypoxia, mesangial cells in the kidney are stimulated to release erythropoietin. This is regulated primarily by the transcription factor hypoxia-induced factor 2 (HIF-2). HIF-2 is degraded by iron and hence during hypoxia, when iron levels are low, the raised HIF-2 levels stimulate more erythropoietin release.
10026463
d
STAT3
Concept
Chapter
2693
3952
Endocrine function of the kidney
Topic
168
Renal Physiology
17690
Which of the following is the correct transcription factor that regulates the release of erythropoietin?
a