QuestionSBA
QuestionChoice
Hypertrophy refers to an increase in the size of cells. It does not describe the cellular changes seen in Barrett's oesophagus.
10025744
e
Hypertrophy
QuestionChoice
Neoplasia refers to the autonomous and uncontrolled growth of cells. This may be benign, or malignant in the case of cancer. It involves the growth of new tissue, whereas Barrett's oesophagus refers to a change in the cellular constituents of tissue. This answer is therefore incorrect.
10025742
c
Neoplasia
QuestionChoice
Dysplasia is the replacement of a mature cell type with an immature or abnormal cell type. Although Barrett's oesophagus can become dysplastic, the above endoscopy report identifies a change to columnar epithelium; a mature cell type. This answer is therefore incorrect.
10025741
b
Dysplasia
QuestionChoice
Hypoplasia describes a lack of cells in tissues. It does not describe the cellular changes seen in Barrett's oesophagus.
10025743
d
Hypoplasia
QuestionChoice
Metaplasia is the replacement of one mature cell type with another and is pathognomonic of Barrett's oesophagus
10025740
a
Metaplasia
Concept
Chapter
2693
4350
Barrett's oesophagus
Topic
136
Gastroenterology
17546
A 55 year old female patient attends the GP surgery to discuss the results of her recent endoscopy. She has chronic dyspepsia and has smoked one packet of cigarettes a day for the last 35 years.

The report identifies a change in the epithelial lining of the lower oesophagus from squamous to columnar epithelium. The GP explains these changes are consistent with a diagnosis of Barrett's oesophagus.

Which of the following best describes the cellular changes identified on endoscopy?
a