QuestionSBA
QuestionChoice
This is an oncogene associated with multiple types of cancer such as pancreatic, colon, bladder, and kidney. While it can be found to be mutated in breast cancer, it is not as common as BRCA 1 and BRCA 2.
10008029
e
RAS
QuestionChoice
BRCA 1 (and BRCA 2) are the most common genes associated with familial breast cancer. BRCA 1 is found on chromosome 17 and mutations are inherited in an autosomal dominant pattern.
10008025
a
BRCA1
QuestionChoice
This is a tumour suppressor gene associated with an increased risk of developing various types of cancer. However, it is not specifically associated with breast cancer compared to BRCA 1 and BRCA 2.
10008027
c
P53
QuestionChoice
This is a tumour suppressor gene associated with retinoblastoma.
10008028
d
pRb
QuestionChoice
Mutations in the APC gene cause the development of polyps in the colon, thus causing colon cancer.
10008026
b
APC
Concept
Chapter
2693
3779
Breast Cancer
Topic
151
Breast Disease
14152
A 35-year-old woman attends an oncology clinic to assess her response to breast cancer treatment. She is keen to know whether her cancer is hereditary, and whether her two daughters are at risk.

Which of the following genes is most associated with an increased risk of developing breast cancer?
a