QuestionSBA
QuestionChoice
Barrett's may progress to an adenocarcinoma which would be a neoplasm. However, Barrett's by itself is not a malignant condition.
10027758
c
Neoplasia of the distal oesophagus
QuestionChoice
There is damage to the oesophagus in Barrett's, but it does not cause tearing. It damages the cells themselves rather than the structure.
10027760
e
Oesophageal tears
QuestionChoice
Dysplasia refers to the presence of abnormal cells- which can sometimes be present in later stages of Barrett's. However, this is not always the case so does not make up the usual pathophysiology.
10027757
b
Dysplasia of the distal oesophagus
QuestionChoice
This would more closely describe achalasia, which would present with difficulty swallowing rather than reflux.
10027759
d
Narrowing of the oesophagus
QuestionChoice
The normal oesophageal epithelium is stratified squamous. In long-term exposure to stomach acid, this changes to columnar epithelium like in the stomach. This change from one cell type to another is called metaplasia.
10027756
a
Metaplasia of the distal oesophagus
Concept
Chapter
2693
4350
Barrett's oesophagus
Topic
136
Gastroenterology
17949
A 45-year-old woman presents for a review. She has had ongoing dyspepsia which is not controlled with omeprazole. This has been occurring for most of her adult life. She is at risk of Barrett's oesophagus due to this.

Which of the following best describes the pathophysiology of Barrett's oesophagus?
a