QuestionSBA
QuestionChoice
Rather than excessive salivation, sertraline more commonly causes dry mouth
34123
d
Sertraline can lead to excessive salivation
QuestionChoice
Patients should discuss with their doctors before stopping the medication because an abrupt discontinuation could lead to discontinuation symptoms such as restlessness and irritability. Besides that, sertraline has not been shown to cause addiction problems
34122
c
He should discontinue his medication once he feels better as sertraline is linked to addiction
QuestionChoice
Sertraline is linked to low sex drive and erectile dysfunction
34124
e
Sertraline can lead to increased sex drive
QuestionChoice
Sertraline is a selective serotonin reuptake inhibitor (SSRI) that works by increasing serotonin levels in the brain. An increase in serotonin levels has been shown to bring about an improvement in symptoms
34121
b
Sertraline works by increasing dopamine levels in the brain
QuestionChoice
Sertraline is a selective serotonin reuptake inhibitor (SSRI) that works by increasing serotonin levels in the brain. It is important to highlight to the patients about the gradual development of full antidepressant effect of SSRI. Patients should be advised to not stop the medication early on even though they might not have felt an improvement because SSRI usually needs to be taken for up to 6 weeks before the benefit is felt
34120
a
He should continue taking the medication even if he does not feel any improvements in the first 6 weeks
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

2618
2768
SSRI considerations
Topic
90
Psychiatry
6835
Case presentation: A 25-year-old man attends his GP with a 3-month history of low mood and energy. He reports that he no can no longer derive joy from gardening which he used to enjoy. He denies having any suicidal ideation.  

Physical examination: HS 1+11 + 0, vesicular breathing with no added lung sounds, abdomen SNT, normal neurological exam
Questionnaire: Patient Health Questionnaire (PHQ-9) score is 10/27.
He has previously tried computerised cognitive behavioural therapy but found it to be less effective. The patient is advised to commence treatment with sertraline 50mg PO daily and attend another appointment in two weeks’ time to review the medication.

Question: Select the most important information that should be provided for this patient.
a