QuestionMultiA
QuestionChoice
33766
e
Verapamil;120mg;oral (PO);Thrice daily
QuestionChoice
33768
g
Allopurinol;100mg;oral (PO);Daily
QuestionChoice
33763
b
Levetiracetam;750mg;oral (PO);Twice daily
QuestionChoice
33767
f
Adalimumab;40mg;subcutaneous (SC);Two-weekly
QuestionChoice
33762
a
Bisoprolol fumarate;10mg;oral (PO);Daily
QuestionChoice
33764
c
Ibuprofen;400mg;oral (PO);Thrice times daily
QuestionChoice
33765
d
Sodium valproate;3.6g;oral (PO);Daily
QuestionChoice
33769
h
Fusidic acid;250mg;oral (PO);Twice daily
QuestionComment
I don't know if I'm being an idiot but 30mg/kg is 3.6g?? eg. the dose he is on
19753
QuestionComment
the max is 2.5g tho so that's the only reason 

27208
User
subscriber
Cristiano Ronaldo 7
User
subscriber
sophieaislinn
QuestionComment
should one of the dosing errors be levetiracetam?
61640
User
subscriber
Abscess Chronic
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

2618
2709
P450 inhibitor and Warfarin
Topic
9
Internal Medicine
1. Beta blockers and non-dihydropyridine calcium channel blockers should not be co-prescribed as both exert a negative inotropic and chronotropic effect on the heart, causing a depression in both mechanical and electrical activity resulting in bradycardia and hypotension.
2. Sodium valproate used for seizure management is prescribed at 20-30mg/kg daily. However, the maximum recommended dose is 2.5g daily. Hence this patient should only be prescribed 2.5g daily and not 3.6g daily. 
6776
a e
d
Case presentation: A 50-year-old man is admitted to the Cardiology ward following an episode of syncope. PH Angina, Seizure, AF, Ankylosing spondylitis, Gout, Cellulitis. DH. His regular medicines are listed (below). Weight 120kg.


**On Examination**
HR 50/min, BP 95/85mm Hg, RR 18, O2 sats 94% RA. HS I + II with no added heart sounds.

Question 1: Select the TWO prescriptions that should not be co-prescribed. (mark them with a tick in column A)
Question 2: Select the ONE prescription that contains a serious dosing error (mark it with a tick in column B).