QuestionSBA
QuestionChoice
This describes the development of GnRH-releasing neurons. This process is disrupted in Kallmann syndrome resulting in an impaired sense of smell and delayed puberty.
10001073
c
Migration of GnRH-releasing neurons from the nasal placode to the hypothalamus
QuestionChoice
This is the process of Wallerian degeneration which occurs after axonotmesis or neurotmesis as the distal aspect of the axon is detached from its cell body.
10001071
a
Schwann cells dissociate from the axon and macrophages remove axon debris
QuestionChoice
This process is known as neural pruning which peaks between ages 2 and 16 to remove unused neurons, improving the strength of connections between more frequently utilised neurons.

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10001075
e
The degeneration of central neurons due to insufficient signalling through them during development
QuestionChoice
This is the process by which neuron axons link to their target structures in embryonic stages and during peripheral nerve regeneration after Wallerian degeneration (it is only likely to be successful after axonotmesis as the growth cone can be guided by the endoneurium, whilst after neurotmesis, the growth cone may not meet the epineurium).
10001072
b
Axon growth cones follow the concentration gradient of neurotrophic factors to the target tissue
QuestionChoice
This process is known as disuse atrophy, which occurs, for example, to the muscles of the thenar eminence in median nerve palsies.
10001074
d
Degeneration of muscular tissue upon denervation
Concept
Chapter
2693
3878
Wallerian degeneration
Topic
152
Neuroscience
12761
Which of these statements best describes Wallerian degeneration?
a