QuestionQA
QuestionComment
Is not 140mg since she received 70mg in 12 hours so in 24hrs she will have received 140mg? 
61513
QuestionComment
it would be 0.5 milligrams times 70kg (500micrograms/kg) which is 35 in 12 hours, then times by 2 to get 70mg in the day :) hope that helps!
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amiina_hx
QuestionComment
45 mcg in the first 6h, nothing for the next 12h followed by a repeat 45mcg in the last 6h of the day
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Recessive Kinin
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Abscess Chronic
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

2618
2853
Drug Calculations
Topic
90
Psychiatry
Dose of diazepam = 500micrograms/kg
Weight = 70kg
Each dose of diazepam
= 500micrograms/kg x 70kg
= 35 000 micrograms = 35mg
Total dose in 24 hours
= 35mg x 2 = 70mg
6921
QuestionQAAnswer
70
mg
A 45-year-old woman in the Psychiatric Ward with severe agitation on admission was started on diazepam 500 micrograms/kg by slow IV infusion over 6 hours. 12 hours after the completion of this infusion, she requires a repeat diazepam infusion. Weight 70kg.


What is the total dose (mg) of diazepam that she will receive over the 24 hour period since her admission?