QuestionSBA
QuestionChoice
Secretin is a hormone produced by the small intestine that regulates fluid and electrolyte secretion. Zollinger-Ellison syndrome does not directly influence secretin production.
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d
Overproduction of secretin
QuestionChoice
Insulin is produced by the pancreas and regulates glucose metabolism. Zollinger-Ellison syndrome does not directly influence insulin production.
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c
Overproduction of insulin
QuestionChoice
Zollinger-Ellison syndrome is characterised by an increase in the production of gastric acid, not a decrease.
10007132
b
Reduced production of gastric acid
QuestionChoice
Zollinger-Ellison syndrome occurs when tumour(s), or gastrinomas, occur in the pancreas or duodenum. These gastrinomas produce large amounts of gastrin, which stimulates the production of gastric acid. This leads to excessive acid secretion and the development of peptic ulcers. Symptoms include nausea, vomiting, diarrhoea, and weight loss.
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a
Increased production of gastric acid
QuestionChoice
CCK is a hormone produced by the small intestine that stimulates release of digestive enzymes from the pancreas and bile from the gall bladder. Zollinger-Ellison syndrome does not directly influence CCK production.
10007135
e
Overproduction of cholecystokinin (CCK)
Concept
Chapter
2693
4572
Zollinger-Ellison Syndrome
Topic
136
Gastroenterology
13973
A 43-year-old male presents to A&E with severe epigastric pain and diarrhoea. He has known peptic ulcer disease and has been taking antacids for the past year. However his symptoms have worsened, and he is diagnosed with Zollinger-Ellison syndrome.

Which of the following describes the underlying pathophysiology of cause of Zollinger-Ellison syndrome?
a