QuestionSBA
QuestionChoice
This patient is presenting with the signs and symptoms of Cushing's syndrome. A fluid deprivation test would be the test of choice for diabetes insipidus. Diabetes insipidus would present with symptoms like excessive thirst and producing large amounts of urine.
10025068
d
Fluid deprivation test
QuestionChoice
The patient in the question is presenting with with central obesity, proximal weakness, depression and abdominal striae are typical of Cushing’s syndrome. A short synacthen test is the test of choice for adrenal sufficiency, not Cushing’s disease. Adrenal insufficiency would present with symptoms like hypotension, fatigue and weakness, gastrointestinal symptoms, and skin pigmentation.
10025066
b
Short synacthen test
QuestionChoice
This is a typical presentation of a patient with Cushing's syndrome: low mood, weight gain, proximal myopathy and abdominal striae. Cushing's syndrome can also cause a moon-shaped face, a "buffalo hump" on the back, diabetes mellitus and hypokalaemia. The diagnostic investigation of choice for Cushing’s syndrome is a dexamethasone suppression test.
10025065
a
Dexamethasone suppression test
QuestionChoice
This patient is presenting with Cushing's syndrome, and therefore a dexamethasone suppression test would be the diagnostic test of choice. You could conduct a HbA1c if you suspected diabetes mellitus, but the diagnosis of Cushing's Syndrome would be confirmed with a dexamethasone suppression test.
10025069
e
HbA1c
QuestionChoice
The patient in the question is presenting with with central obesity, proximal weakness, depression and abdominal striae are typical of Cushing’s syndrome. 24-hour plasma metanephrines would be the correct test if you suspected a pheochromocytoma. This would present with episodes of hypertension, anxiety and headaches. Therefore, the correct answer to this question is to conduct a dexamethasone suppression test.
10025067
c
24-hour plasma metanephrines
Concept
Chapter
2693
3764
Cushing's syndrome
Topic
133
Endocrinology
17411
A 19-year-old female presents to her GP with low mood. She describes experiencing weight gain, particularly around her abdomen, over the last six months despite attempts to loose weight. On examination, you notice weakness in all four proximal limbs, as well as circular hump on the back and a circular-shaped face.

Which of the following investigations would confirm the most likely diagnosis?
a