QuestionSBA
QuestionChoice
This is incorrect. This describes Conn's syndrome whereby a loss of aldosterone release suppression leads to abnormally high levels of aldosterone and hence increased sodium (and water) reabsorption. Nephrogenic diabetes insipidus is a form of diabetes insipidus whereby the kidney loses its sensitivity to ADH. This means ADH no longer exerts its function to reabsorb water leading to inappropriately high levels of water loss in the urine.
10026413
d
An inability to suppress aldosterone release
QuestionChoice
This incorrect. Nephrogenic diabetes insipidus does not affect aldosterone. Nephrogenic diabetes insipidus is a form of diabetes insipidus whereby the kidney loses its sensitivity to ADH. This means ADH no longer exerts its function to reabsorb water leading to inappropriately high levels of water loss in the urine.
10026414
e
A loss of aldosterone release
QuestionChoice
This is incorrect. This describes the pathophysiology of SIADH whereby the loss of ADH release suppression leads to inappropriately high levels of ADH causing excess water reabsorption. Nephrogenic diabetes insipidus is a form of diabetes insipidus whereby the kidney loses its sensitivity to ADH. This means ADH no longer exerts its function to reabsorb water leading to inappropriately high levels of water loss in the urine.
10026412
c
An inability to suppress ADH release
QuestionChoice
This is correct. Nephrogenic diabetes insipidus is a form of diabetes insipidus whereby the kidney loses its sensitivity to ADH. This means ADH no longer exerts its function to reabsorb water leading to inappropriately high levels of water loss in the urine.
10026410
a
Loss of sensitivity of the kidneys to ADH
QuestionChoice
This is incorrect. This describes central diabetes insipidus whereby there is defective ADH secretion from the posterior pituitary. Nephrogenic diabetes insipidus is a form of diabetes insipidus whereby the kidney loses its sensitivity to ADH. This means ADH no longer exerts its function to reabsorb water leading to inappropriately high levels of water loss in the urine.
10026411
b
Loss of ADH secretion from the posterior pituitary
Concept
Chapter
2693
5892
Diabetes Insipidus
Topic
167
Endocrine physiology
17680
Which of the following correctly describes the pathophysiology of nephrogenic diabetes insipidus?
a