QuestionSBA
QuestionChoice
In heart failure, the ventricular wall is stretched over a favourable point according to the frank-starling mechanism. The actin-myosin overlap becomes ineffective and you actually get a decrease in the force the heart can generate.
10004071
a
An increase in ventricular end-diastolic volume results in reduced stroke volume
QuestionChoice
This is incorrect as it is not in line with the Frank-starling law principles.
10004074
d
Increased cardiac output with reduced ventricular end-diastolic pressure
QuestionChoice
This is the frank starling law under normal physiological conditions. In heart failure, this relationship fails.
10004072
b
As ventricular end-diastolic pressure increases, cardiac output increases
QuestionChoice
This is incorrect as in heart failure both cardiac output and end-diastolic pressure are affected.
10004075
e
Cardiac output and end-diastolic pressure do not change
QuestionChoice
In heart failure, while cardiac output is reduced, ventricular end-diastolic volume continues to increase as there is a backlog of blood failing to be pumped around the body. Therefore this answer is incorrect.
10004073
c
The ventricular end-diastolic volume reduces along with the cardiac output
Concept
Chapter
2693
4230
Frank-Starling Curve
Topic
159
Cardiovascular physiology
13361
Which of the following describes the relationship between stroke volume and end-diastolic volume in heart failure according to the Frank-Starling Law?
a