QuestionSBA
QuestionChoice
Angiotensin is a hormone which regulates vasoconstriction and triggers water and sodium retention. Both of these functions lead to increased blood volume and pressure. It does not play a role in diabetes insipidus.
10004950
e
Increased angiotensin
QuestionChoice
Diabetes insipidus is characterised by an abnormal quantity (cranial cause) or insensitivity in response to antidiuretic hormone (nephrogenic causes). Antidiuretic hormone (ADH) regulates blood pressure by controlling water retention in the kidneys, thus changing urine output. Decreased secretion of ADH will lead to decreased urine retention and thus excessive urine output.
10004946
a
Decreased secretion of antidiuretic hormone (ADH)
QuestionChoice
Aldosterone is a hormone which regulates the amount of sodium and water retention. Increased aldosterone will lead to water retention which increased blood volume and pressure. Aldosterone, however, is not the hormone affected in diabetes insipidus.
10004948
c
Increased secretion of aldosterone
QuestionChoice
Aldosterone is a hormone which regulates the amount of sodium and water retention. Decreased aldosterone will lead to less water retention which decreases blood volume and pressure. Aldosterone, however, is not the hormone affected in diabetes insipidus.
10004949
d
Decreased secretion of aldosterone
QuestionChoice
Diabetes insipidus is characterised by an abnormal quantity (cranial cause) or insensitivity in response to antidiuretic hormone (nephrogenic causes). Antidiuretic hormone (ADH) regulates blood pressure by controlling water retention in the kidneys, thus changing urine output. Increased secretion of ADH will lead to increased urine retention and thus decreased urine output. This is not what is described in the question stem.
10004947
b
Increased secretion of antidiuretic hormone (ADH)
Concept
Chapter
2693
3754
Diabetes insipidus
Topic
133
Endocrinology
13536
An 18-year-old male presents to his GP with symptoms of increased thirst and abnormally increased urine output. A urine dip test comes back with inappropriately dilute urine, and a glucose finger prick test rules out diabetes mellitus.

The patient is diagnosed with diabetes insipidus.

Which of the following describes the most likely mechanism causing this patient's presentation and results?
a