QuestionSBA
QuestionChoice
Pramipexole is linked with impulsive control disorders such as binge eating, pathological gambling and hypersexuality. 
34105
a
Pramipexole is associated with impulsive control disorder
QuestionChoice
Pramipexole increases risk of postural hypotension, especially at the start of treatment. Hence, it is recommended to monitor the blood pressure of patients on initiation of the treatment
34109
e
Pramipexole could lead to high blood pressure
QuestionChoice
Patients are usually given a small dose to start with before the dose gets gradually increased over time to reduce side effects such as dizziness
34107
c
Maximum dose of pramipexole is usually given at the start to ensure complete control of the symptoms
QuestionChoice
Pramipexole is a dopamine-receptor agonist that is used alone or as an adjunct to co-careldopa or co-beneldopa to treat Parkinson’s disease
34106
b
Pramipexole is converted into dopamine in the body
QuestionChoice
Dose of pramipexole needs to be reduced gradually before it can be stopped completely to reduce the risk of neuroleptic malignant syndrome(NMS). NMS is characterised by fever, altered mental status, muscle rigidity and autonomic dysfunction
34108
d
He should immediately stop taking pramipexole if it causes him to feel dizzy
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

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Pramipexole side effects
Topic
74
Elderly Care
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Case presentation: A 65-year-old man attends the Parkinson clinic with increasing frequencies of involuntary and uncontrollable movement.  

PMH: Parkinson’s disease, Diabetes Mellitus, Hypertension
DH: Co-Beneldopa (immediate-release) 200mg PO QDS, Metformin hydrochloride 500mg PO TDS, Captopril 50mg PO BD
The patient is advised to add pramipexole 88 micrograms PO TDS as an adjunct to his current treatment regime to help control the dyskinesia.

Question: Select the most important information that should be provided for this patient.
a