QuestionSBA
QuestionChoice
An example of a GLP-1 analogue is exenatide, which works by increasing insulin secretion and sensitivity. However, sitagliptin is a DPP4 inhibitor.
10008081
b
GLP-1 analogues
QuestionChoice
Metformin is the most common example of a biguanide. It works by increasing peripheral insulin sensitivity and hepatic glucose uptake. However, sitagliptin is a DPP4 inhibitor.
10008082
c
Biguanides
QuestionChoice
Sitagliptin works by inhibiting DPP4, which in turn increases levels of incretins (GLP-1 and GIP) by decreasing their peripheral breakdown.
10008080
a
DPP4-Inhibitors
QuestionChoice
Dapagliflozin is an SGLT2 inhibitor and works by increasing urinary glucose loss. However, sitagliptin is a DPP4 inhibitor.
10008083
d
SGLT2 inhibitors
QuestionChoice
An example of a sulfonylurea is gliclazide, which works by depolarising islet cells in the pancreas thus increasing insulin release. By contrast, sitagliptin is a DPP4 inhibitor.
10008084
e
Sulfonlyureas
Concept
Chapter
2693
4642
Anti-diabetic drugs mechanism of action
Topic
133
Endocrinology
14163
A 54-year-old male patient with a previous diagnosis of type II diabetes is taking a medication called sitagliptin.

Which of the following classes of medication does sitagliptin belong to?
a