QuestionSBA
QuestionChoice
Increased temperature **decreases** Hb-O2 binding affinity, decreasing oxygen saturation at a given partial pressure of oxygen and effectively releasing oxygen from haemoglobin.
10024344
e
High temperature increases haemoglobin-oxygen (Hb-O2) affinity and decreases O2 unloading from haemoglobin
QuestionChoice
A high pH (alkalosis) **increases** haemoglobin-oxygen binding as it decreases the rate of ligand dissociation. This allows for a higher rate of oxygen binding in the lungs where there is a lower pCO2 and the environment is more alkalotic.
10024341
b
High pH decreases haemoglobin-oxygen (Hb-O2) affinity and increases O2 unloading from haemoglobin
QuestionChoice
Increased 2,3-diphosphoglycerate (2,3-DPG) **decreases** Hb-O2 binding affinity, decreasing oxygen saturation at a given partial pressure of oxygen and effectively releasing oxygen from haemoglobin.
10024343
d
High 2,3-diphosphoglycerate (2,3-DPG) increases haemoglobin-oxygen (Hb-O2) affinity and decreases O2 unloading from haemoglobin
QuestionChoice
At the site of respiration, there is a high pCO2 due to the production of waste products. Carbon dioxide increases hydrogen ion concentration which causes acidosis (low pH). This increases ligand dissociation and promotes the release of oxygen from haemoglobin.
10024340
a
High pCO2 decreases haemoglobin-oxygen (Hb-O2) affinity and increases oxygen unloading from haemoglobin
QuestionChoice
Increased temperature decreases Hb-O2 binding affinity, decreasing oxygen saturation at a given partial pressure of oxygen and effectively releasing oxygen from haemoglobin.
10024342
c
High temperature increases haemoglobin-oxygen (Hb-O2) affinity and increases O2 unloading from haemoglobin
Concept
Chapter
2693
5769
Gaseous exchange and transportation
Topic
150
Respiratory physiology
17266
Oxygen-haemoglobin binding is affected by several factors.

Which of the following statements is correct?
a