QuestionSBA
QuestionChoice
The two main pathophysiological changes which occur in Alzheimer's disease are the build-up of beta-amyloid plaques and the development of neurofibrillary tangles. As a result of these changes, there is a reduction in the neuronal connections within the brain, which leads to symptoms of dementia.
10002462
a
Formation of neurofibrillary tangles
QuestionChoice
Autoimmune demyelination of neurones is more commonly seen in multiple sclerosis, as opposed to Alzheimer's disease.
10002466
e
Autoimmune demyelination of neurones
QuestionChoice
Loss of dopaminergic neurones in the substantia nigra occurs in Parkinson's disease, as opposed to Alzheimer's disease.
10002463
b
Loss of dopaminergic neurones
QuestionChoice
Although deposition of alpha-synuclein may be seen in some cases of Alzheimer's disease, it is more commonly seen in Lewy body dementia and Parkinson's disease.
10002465
d
Deposition of alpha-synuclein
QuestionChoice
Loss of brainstem motor nuclei occurs in motor neurone disease, as opposed to Alzheimer's disease.
10002464
c
Loss of brainstem motor nuclei
Concept
Chapter
2693
4042
Alzheimer's disease
Topic
191
Geriatrics
13039
Which of the following pathophysiological changes are most likely to be seen in Alzheimer's disease?
a