QuestionSBA
QuestionChoice
The combined oral contraceptive pill thickens cervical mucus. This makes it harder for sperm to reach the oocyte and therefore gives its contraceptive properties.
10025787
c
Thinning of the cervical mucus
QuestionChoice
This is incorrect as the combined oral contraceptive pill is not used in patients who have sperm cells, or who produce semen. The COCP contains both oestrogen and progesterone. This in turn inhibits the release of FSH and LH through negative feedback, as well as causing thickening of the cervical mucus which makes it more difficult for sperm to penetrate. It also inhibits endometrial proliferation, which prevents implantation.
10025789
e
Reduces the number of sperm cells in semen
QuestionChoice
Endometrial proliferation is part of the normal physiological process of the menstrual cycle to facilitate implantation of the oocyte to the endometrium and therefore fertilisation. The high levels of oestrogen and progesterone inhibit this process preventing implantation and therefore fertilisation of the oocyte.
10025788
d
Inducing endometrial proliferation
QuestionChoice
The COCP contains both oestrogen and progesterone. This in turn inhibits the release of FSH and LH through negative feedback, as well as causing thickening of the cervical mucus which makes it more difficult for sperm to penetrate the uterus. It also inhibits endometrial proliferation, which prevents implantation. Thickening of the cervical mucus therefore correctly describes a component of the mechanism of action of the COCP.
10025785
a
Thickening of the cervical mucus
QuestionChoice
The combined oral contraceptive pill contains oestrogen and progesterone. It actually reduces levels of FSH and LH, which inhibits ovulation.
10025786
b
High LH and FSH levels inhibit oestrogen and progesterone levels
Concept
Chapter
2693
5862
Contraception
Topic
175
Reproductive Physiology
17555
A 19 year old female comes to her GP to discuss contraceptive options. After discussion, she decides that she would like to try the combined oral contraceptive pill (COCP).

Which of the following describes the mechanism of action of this drug?
a