QuestionSBA
QuestionChoice
Cyclizine is a histamine (H1) receptor antagonist. Therefore, it is safe to use in Parkinson's disease as it does not affect the dopamine levels in the brain.
10027948
c
Cyclizine
QuestionChoice
Ondansetron is the first-line anti-emetic drug. It is a serotonin (5HT3) receptor antagonist and acts centrally in the chemotherapy trigger zone. As it is not affecting the dopamine levels in the brain, it is safe to use with Parkinson's disease.
10027947
b
Ondansetron
QuestionChoice
Hyoscine hydrobromide is an example of an anti-muscarinic. It is an antagonist of the muscarinic receptors in the chemoreceptor trigger zone in the brain. It is safe for use in Parkinson's disease as it is not affecting dopamine levels in the brain.
10027949
d
Hyoscine hydrobromide
QuestionChoice
Metaclopramide is a dopamine (D2) receptor antagonist. This will worsen Parkinson's symptoms as Parkinson's is caused by a lack of dopamine.
10027946
a
Metoclopramide
QuestionChoice
Dexamethasone is a corticosteroid that is used as an anti-emetic alongside some chemotherapy agents. It is safe for use in Parkinson's disease as dopamine is not suppressed in the brain.
10027950
e
Dexamethasone
Concept
Chapter
2693
6020
Anti-emetics
Topic
195
Pharmacology
17987
Due to its mechanism of action, which anti-emetic is contraindicated in patients with Parkinson's disease?
a