QuestionSBA
QuestionChoice
Macrocytes are abnormally large red blood cells, which can be seen in vitamin B12 and folate deficiency, but not in iron deficiency anaemia.
10002038
b
Macrocytes
QuestionChoice
Target cells are most likely to be seen on a blood film in iron deficiency anaemia. Target cells are red blood cells that have a characteristic bull's-eye appearance on a blood film, caused by a decrease in the amount of haemoglobin in the cells. They are seen in iron deficiency anaemia due to a lack of iron available for the production of haemoglobin, and thus a decreased amount of haemoglobin in cells. The bull's-eye appearance is caused by a relative excess of cell membrane due to a reduced intracellular haemoglobin content (increased cell membrane area to volume ratio).
10002037
a
Target cells
QuestionChoice
Sickle cells are crescent-shaped red blood cells which are seen in sickle cell anaemia. They are caused by a genetic mutation in the beta-globin gene, which leads to the formation of abnormal haemoglobin. They are not typically seen in iron deficiency anaemia.
10002039
c
Sickle cells
QuestionChoice
Keratocytes, or bite cells, are red blood cells with a bite-like defect in their membrane. They occur as a result of the phagocytosis of a Heinz body (which is made up of denatured haemoglobin), which leaves a bite-like deformity in the cell. They are not typically seen in iron deficiency anaemia.
10002040
d
Keratocytes
QuestionChoice
Schistocytes are fragmented red blood cells which can be seen in certain types of haemolytic anaemia, such as haemolytic uraemic syndrome (HUS), disseminated intravascular coagulation (DIC) and thrombotic thrombocytopenic purpura (TTP). They are not typically seen in iron deficiency anaemia.
10002041
e
Schistocytes
Concept
Chapter
2693
4004
Anaemia
Topic
157
Haematology
12954
Which of the following cells is most likely to be seen on a blood film in iron deficiency anaemia?
a