QuestionSBA
QuestionChoice
Amiloride and Triamterene bind to epithelial sodium channels, known as ENaC, to inhibit sodium reabsorption and potassium loss.
10024278
d
Epithelial sodium channels in the collecting duct
QuestionChoice
This is the site where carbonic anhydrase works. This reduces the availability of hydrogen ions in the lumen and increases the excretion of sodium, bicarbonate and water.
10024276
b
Na-H channels in the proximal convoluted tubule
QuestionChoice
The thick ascending loop of Henle is where loop diuretics, such as furosemide, exert their effects.
10024279
e
Na-K-Cl channels in the loop of Henle
QuestionChoice
Aldosterone receptor antagonists competitively bind to receptors on sodium-potassium channels in the distal convoluted tubule. This causes the excretion of sodium and water and the retention of potassium. They are therefore also known as potassium-sparing diuretics.
10024277
c
Na-K channels in the distal convoluted tubule
QuestionChoice
Thiazide diuretics inhibit Na and Cl uptake via a co-transporter in the distal convoluted tubule.
10024275
a
Na-Cl channels in the distal convoluted tubule
Concept
Chapter
2693
5764
Thiazide diuretics
Topic
188
Renal Pharmacology
17253
A 40-year-old patient taking thiazide diuretics presents with nausea, muscle cramps and palpitations. His ABG shows a potassium level of 2.5mmol/L (3.5-5.3 mmol/L).


Where in the nephrons do thiazide diuretics act?
a