QuestionSBA
QuestionChoice
These ducts arise from the seminal vesicles and ductus deferens. These pass through the central zone but are not part of the prostate itself.
10005814
d
Ejaculatory ducts
QuestionChoice
This case is suggestive of prostate cancer due to the raised PSA and a DRE suggestive of a malignant growth.

You would expect the prostate to feel smooth and spongy with a central sulcus. In prostate cancer, it tends to feel harder and nodular with a loss of the sulcus.

PSA is often not very specific as it can be raised in other circumstances such as in infection, following recent ejaculation and cycling. It is therefore not routinely tested for but those over 50 can ask the GP for a test if they would like one.

Most cancers arise in the peripheral zone and are further away from the urethra. The peripheral zone consists of mainly glandular tissue so often produces of adenocarcinomas. They do not always cause urinary symptoms in early disease.
10005811
a
Peripheral zone
QuestionChoice
This part of the prostate surrounds the ejaculatory ducts and is a common site for BPH but not prostate cancer.
10005813
c
Central zone
QuestionChoice
As men get older over the age of 50, the prostate gland naturally becomes larger. This is known as benign prostatic hyperplasia.

This most likely arises in the transition zone of the prostate. This is what surrounds the urethra and is most likely to cause lower urinary tract symptoms such as nocturia, frequency, urgency and post-micturition dribbling.
10005812
b
Transition zone
QuestionChoice
There are four major zones of a normal prostate: the peripheral zone, the central zone, the transition zone and the anterior fibromuscular stroma.

The anterior fibromuscular stroma has no glandular tissue and is not a common site for prostate cancer or BPH.
10005815
e
Anterior fibromuscular stroma
Concept
Chapter
2693
3755
Prostate cancer
Topic
143
Urology
13709
60 year old attends the GP concerned that he may have prostate cancer. He is aware that his father died from prostate cancer and is now seeing a lot about it in the media. He explains he feels as though he is going to the toilet more to empty his bladder at night.

The GP decides to measure the prostate-specific antigen (PSA) and perform a digital rectal examination (DRE).

PSA is raised and DRE reveals a slightly hard, craggy prostate.

Where is the most common site for prostate cancers?
a