QuestionSBA
QuestionChoice
Calcium is not typically affected by ACTH and cortisol. Hypercalcaemia is more common in squamous cell carcinoma of the lung due to PTHrp production.
10005625
e
Hypercalcaemia
QuestionChoice
Ectopic ACTH release causes increased cortisol secretion and therefore Cushing's syndrome. Increased cortisol increases sodium retention and potassium excretion so hypernatraemia would be more likely.
10005622
b
Hyponatraemia
QuestionChoice
Ectopic ACTH release causes increased cortisol secretion and therefore Cushing's syndrome. Increased cortisol increases sodium retention and potassium excretion.
10005621
a
Hypokalaemia
QuestionChoice
ACTH causes increased cortisol secretion. Cortisol is responsible for stimulating gluconeogenesis and lipolysis. Therefore, blood glucose levels are usually increased.
10005624
d
Low blood glucose
QuestionChoice
ACTH stimulates the adrenal cortex to produce cortisol and so there would be high cortisol.
10005623
c
Low morning cortisol
Concept
Chapter
2693
3702
Lung Cancer
Topic
132
Respiratory
13671
Small cell lung cancer can cause ectopic ACTH production.

If this occurs, which of the following biochemical abnormalities is most likely to be present?
a