QuestionSBA
QuestionChoice
The spliceosome mediates RNA splicing at GT-AG consensus sequences. A 2' -OH group from the 3' end of an intron undergoes hydrophilic attack of a phosphate group at the 5' end of the intron, and is followed by the newly free 3' -OH group of the 5' exon attacking the phosphate of the 3' exon. This results in the removal of the intron in a circular lariat. Rho is not involved.

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10001140
e
pre-mRNA splicing
QuestionChoice
The stop codons UAA, UAG and UGA are complementary to release factor, a protein which binds to the A-site of the ribosome and causes the dissociation of the small and large ribosomal subunits. Rho is not involved.
10001138
c
Termination of translation
QuestionChoice
Transcription is initiated when a promoter site is bound by the components of the pre-initiation complex. In eukaryotes, there is a TATA consensus motif 25 bases upstream of the translation start site to which TF2D (with the TATA-binding protein), other general transcription factors and RNA polymerase 2 bind to form the pre-initiation complex. Rho is not involved.
10001137
b
Initiation of transcription
QuestionChoice
Rho-dependent termination occurs when the rho RNA helicase binds newly-translated C-rich RNA followed by a GC-rich hairpin and unwinds the RNA-DNA complex to mediate dissociation. In contrast, rho-independent termination of transcription occurs when the RNA polymerase reaches a palindromic GC-rich DNA sequence followed by an AT-rich DNA sequence and pauses then dissociates, with the RNA adopting a GC-rich hairpin and a string of uracils.
10001136
a
Termination of transcription
QuestionChoice
Translation is initiated when the small ribosomal subunit binds the 5' m7G cap (or IRES sequence) of an mRNA molecule. It then scans along the mRNA until the AUG start codon, at which point the large ribosomal subunit associates and the methionine tRNA is recruited to the A-site and translation begins. Rho is not involved.
10001139
d
Initiation of translation
Concept
Chapter
2693
3885
Processes in mitosis
Topic
156
Medical Genetics
12774
Rho-dependent could be used to describe which of the following processes?
a