QuestionSBA
QuestionChoice
Correct - Oligodendroglia cells produce myelin in the central nervous system. This affects the conduction velocity of neuronal signalling. They are damaged in patients with multiple sclerosis, thus impairing the transmission of sensory and motor neuronal signalling.
10008355
a
Oligodendroglia
QuestionChoice
Incorrect - Ependymal cells are ciliated cuboidal epithelial cells that form the blood-cerebrospinal fluid barrier. They line the ventricles of the brain and the choroid plexus.
10008359
e
Ependymal
QuestionChoice
Incorrect - Schwann cells produce myelin in the peripheral nervous system. They are not damaged in patients with multiple sclerosis, which targets the central nervous system.
10008356
b
Schwann cells
QuestionChoice
Incorrect - Astrocytes have a homeostatic role within the nervous system. They maintain the blood brain barrier and preserve the chemical environment within the central nervous system by recycling ions and acting as transporters. They co-ordinate blood flow to match local activity, take up neurotransmitters and electrolytes such as potassium, and communicate with other astrocytes through gap junctions.
10008357
c
Astrocytes
QuestionChoice
Incorrect - Microglia cells act as macrophages within the nervous system. Microglia are derived from bone marrow and are activated during injury and infection. They secrete cytokines and present antigens to lymphocytes as part of an immune response.
10008358
d
Microglia
Concept
Chapter
2693
3745
Multiple Sclerosis
Topic
141
Neurology
14218
A 55-year-old woman with multiple sclerosis presents to her GP after noticing a progressive worsening in her symptoms over the past 6 weeks. She reports a sensation similar to an electric shock travelling down her spine and into her legs, that occurs whenever she flexes her neck.

Which of the following cell types is damaged in patients with multiple sclerosis?
a