QuestionSBA
QuestionChoice
Glyceryl Trinitrate (GTN) is a medication used for prophylaxis and treatment of angina. It converts into nitric oxide, leading to vasodilation and increased blood flow to the heart
34171
b
GTN works by making the heart beat faster and stronger so that more blood can be delivered to meet the body’s demand
QuestionChoice
Manufacturer advises against the concurrent use of GTN and sildenafil because it increases the risk of severe hypotension and circulatory collapse
34172
c
GTN can be safely used together with sildenafil
QuestionChoice
Restlessness is a rare side effect of GTN
34174
e
Restlessness is a common side effect of GTN
QuestionChoice
Patients are advised to repeat the dose at 5 minutes interval if required and to seek immediate medical attention if symptoms have not resolved after 2 doses
34170
a
He should seek immediate medical help if symptoms have not resolved after 2 consecutive doses
QuestionChoice
Patients are advised to repeat the dose at 5 minutes interval if required and to seek immediate medical attention if symptoms have not resolved after 3 doses
34173
d
GTN can be taken at 10 minutes interval if required
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

2618
2777
Headache following GTN 
Topic
92
General Practice
6845
Case presentation: A 63-year-old man attends his GP appointment with a 3-month history of chest pain on exertion. He reports that he sometimes gets out of breath and feels a constricting chest pain when climbing up the stairs. The pain usually goes away a few minutes after he sits down.  

PMH: Erectile dysfunction
SH: Retired, lives with his wife

The patient is advised to take Glyceryl Trinitrate (GTN) spray to relieve the chest pain.

Question: Select the most appropriate information that should be provided for this patient.
a