QuestionSBA
QuestionChoice
This history is suggestive of a haemolytic anaemia. we would expect to see corresponding blood film changes such as the presence of schistocytes (red blood cell fragments), spherocytes (in hereditary spherocytosis), bite cells and Heinz bodies (in G6PD deficiency).
10003960
e
Normal blood film
QuestionChoice
This history is suggestive of a haemolytic anaemia. In haemolytic anaemias the haptoglobin is low. Haptoglobin is a plasma protein that binds to free haemoglobin and then is removed from the body. It is low in haemolytic anaemias as red blood cell breakdown results in the release of lots of free haemoglobin which haptoglobin can bind to.
10003956
a
Low haptoglobin
QuestionChoice
This history is suggestive of a haemolytic anaemia. Reticulocytes are immature red blood cells and would be increased in haemolytic anaemias as a compensatory mechanism for the increased red blood cell breakdown.
10003959
d
Reduced reticulocytes
QuestionChoice
This history is suggestive of a haemolytic anaemia. Bilirubin is a breakdown product of haem and would be raised in a haemolytic anaemia, not lowered. It is the increased level of bilirubin that is responsible for the yellow skin pigmentation in this patient (jaundice).
10003958
c
Low bilirubin
QuestionChoice
This history is suggestive of a haemolytic anaemia. Lactate dehydrogenase (LDH) would be expected to be raised in a haemolytic anaemia. LDH is present in red cells and haemolysis causes its release into the plasma.
10003957
b
Low LDH
Concept
Chapter
2693
4220
Haemolytic anaemia
Topic
157
Haematology
13338
A 6-year-old male presents to the paediatric haematology team with his mother.

On examination, the child has a yellow colouring to his skin. The mother states that this has happened before, and the child is becoming increasingly lethargic and irritable.

The haematologist orders further tests.

Which of the following is the most likely test result for this patient?
a