QuestionSBA
QuestionChoice
If this patient was presenting with bony metastases, the bone profile would look slightly different. Bony metastases would cause high levels of calcium and ALP, and low levels of PTH. The phosphate levels would remain in range. The biochemical results in this question suggest a diagnosis of osteomalacia.
10025137
c
Bony metastases
QuestionChoice
Osteoporosis would produce normal bone profile results. It would not explain the low calcium or phosphate levels or the rise in PTH.
10025138
d
Osteoporosis
QuestionChoice
Osteomalacia is caused by low vitamin D levels and results in bone softening. Osteomalacia can cause normal or low levels of calcium or phosphate. It will cause a rise in the levels of alkaline phosphatase (ALP). It can cause normal or high levels of PTH.
10025135
a
Osteomalacia
QuestionChoice
Paget's disease of the bone would present as an isolated rise in ALP levels. It would not explain the low calcium or phosphate, or the rise in PTH levels. Therefore, it is not the most likely diagnosis in this case.
10025136
b
Paget's disease of the bone
QuestionChoice
Primary hyperparathyroidism will cause high levels of calcium, ALP and PTH. It will cause low phosphate levels. The biochemical results in this question suggest a diagnosis of osteomalacia.
10025139
e
Primary hyperparathyroidism
Concept
Chapter
2693
4117
Osteomalacia
Topic
133
Endocrinology
17425
A 20-year-old male comes into the GP for a routine blood test. He is found to have low calcium, low phosphate, low viatmin D levels, and high levels of parathyroid hormone (PTH).

Which of the following is the most likely diagnosis?
a