QuestionSBA
QuestionChoice
This answer is correct. The main actions of BNP are to increase sodium and water excretion and dilate blood vessels. This vasodilation results in a decrease in systemic vascular resistance.
10007256
a
Reduces systemic vascular resistance
QuestionChoice
This answer is incorrect. BNP increases sodium excretion (natriuresis) in order to reduce intravascular blood volume.
10007259
d
Reduces natriuresis
QuestionChoice
This answer is incorrect. BNP inhibits ADH release, which in turn reduces intravascular volume.
10007258
c
Stimulates release of anti-diuretic hormone (ADH)
QuestionChoice
This answer is incorrect. BNP reduces blood pressure by reducing both systemic vascular resistance and intravascular blood volume.
10007257
b
Increases blood pressure
QuestionChoice
This answer is incorrect. BNP inhibits the release of aldosterone from the adrenal glands to promote sodium and water excretion and reduce intravascular volume.
10007260
e
Stimulates release of aldosterone
Concept
Chapter
2693
4582
Heart failure
Topic
159
Cardiovascular physiology
13998
A 78-year-old woman presents to the GP with a 6-month history of worsening breathlessness on exertion and swollen ankles.


On examination, the jugular venous pressure is raised 3cm above normal and there is bilateral pitting oedema to mid-calf.


N-terminal pro B-Type Naturietic Peptide (NT-proBNP) level: 860pg/L (normal: <450 pg/ml in over-75s).


She is referred for an echocardiogram for investigation of heart failure.


Which of the following is true regarding the actions of BNP?
a