QuestionQA
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

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Weight-based dosing
Topic
91
Paediatrics
The dose of amoxicillin normally for an 8-year-old child is 500mg three times a day. This can be increased to 30mg/kg three times a day. Based on the patient's weight of 35kg, the dose would be: 35kg x 30mg/kg = 1050mg. However, there is restricted to the cap of 1g per dose. Since this is given three times a day, the maximum dose is: 1g x 3 times a day = 3g a day.
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QuestionQAAnswer
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g
A 8-year-old patient who weighs 35kg has community-acquired pneumonia. He is prescribed amoxicillin orally.

What is the maximum total dose (in grams) of amoxicillin he can be given per day?