QuestionSBA
QuestionChoice
Alendronic acid reduces the rate of bone turnover
34097
c
Alendronic acid works by increasing the rate of bone turnover
QuestionChoice
Alendronic acid is a bisphosphonate that treats osteoporosis by inhibiting osteoclast-mediated bone resorption
34096
b
Alendronic acid is a Vitamin D3 supplement that helps to strengthen the bone
QuestionChoice
Patients should stop taking alendronic acid if they experience worsening heartburn or chest pain because these symptoms may be suggestive of ulceration
34099
e
It is common for people to experience worsening heartburn while taking the medication and that she should persists as the heartburn usually settles after the first few doses
QuestionChoice
Patients are advised to take it first thing in the morning on an empty stomach
34098
d
She should take it with food to reduce irritation to the food pipe
QuestionChoice
It is important to remind the patients to take it while sitting up or standing and stay upright for 30 minutes after taking it to reduce oesophageal irritation
34095
a
She should take it while siting straight or standing and keep upright for 30 minutes after taking it
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

2618
2763
Alendronic acid
Topic
74
Elderly Care
6830
Case presentation: A 75-year-old woman is admitted to the hospital with left hip pain following a minor fall. She appears frail and has a low body mass index (BMI) of 18kg/m².  

Investigations: Hip x-ray reveals an intracapsular fracture at the neck of femur. Dual-energy x-ray absorptiometry (DEXA) reveals a T-score of -2.8.
A diagnosis of osteoporosis is made and patient is advised to commence treatment with Alendronic acid 70mg PO once weekly.

Question: Select the most important information that should be provided for this patient.
a