QuestionSBA
QuestionChoice
The combination of advanced maternal age and the findings of the combined test suggest that the foetus may have Down's syndrome (trisomy 21). The most common cardiovascular anomaly occurring in Down's syndrome is atrioventricular septal defect. Tetralogy of Fallot has a weaker association with Down's syndrome, and is also associated with Alagille syndrome and DiGeorge syndrome.
10036039
c
Tetralogy of Fallot
QuestionChoice
The combination of advanced maternal age and the findings of the combined test suggest that the foetus may have Down's syndrome (trisomy 21). The most common cardiovascular anomaly occurring in Down's syndrome is atrioventricular septal defect.
10036038
b
Patent foramen ovale
QuestionChoice
The combination of advanced maternal age and the findings of the combined test suggest that the foetus may have Down's syndrome (trisomy 21). The most common cardiovascular anomaly occurring in Down's syndrome is atrioventricular septal defect.
10036040
d
Total anomalous pulmonary venous return
QuestionChoice
The combination of advanced maternal age and the findings of the combined test suggest that the foetus may have Down's syndrome (trisomy 21). The most common cardiovascular anomaly occurring in Down's syndrome is atrioventricular septal defect. Aortic coarctation is commonly associated with Turner syndrome.
10036041
e
Coarctation of the aorta
QuestionChoice
The combination of advanced maternal age and the findings of the combined test suggest that the foetus may have Down's syndrome (trisomy 21). The most common cardiovascular anomaly occurring in Down's syndrome is atrioventricular septal defect.
10036037
a
Atrioventricular septal defect
Concept
Chapter
2693
4603
Down's Syndrome
Topic
153
Paediatrics
19611
Atrioventricular septal defect is the most common cardiac anomaly associated with Down's syndrome.
A 41-year-old pregnant lady is referred to a materno-foetal medicine unit after a cardiovascular anomaly was found on a routine foetal ultrasound scan. A combined screening test in the first trimester showed increased nuchal thickness, a high serum beta-HCG level, and a low Pregnancy-associated plasma protein-A (PAPP-A) level. She opted not to proceed with further pre-natal diagnostics.

What is the most likely cardiovascular anomaly detected?
a