QuestionSBA
QuestionChoice
Incorrect - It is safe for patients with epilepsy to take trimethoprim, provided they are not pregnant. However the BNF should always be consulted for any potential drug interactions.
10008346
b
Epilepsy
QuestionChoice
Incorrect - Trimethoprim is contraindicated in patients with megaloblastic anaemia due to folate deficiency, but it is not contraindicated in patients with iron deficiency anaemia.
10008349
e
Iron Deficiency Anaemia
QuestionChoice
Incorrect - Trimethoprim is typically well tolerated in patients with renal impairment. The BNF recommends the dose be reduced in renal impairment, but it is not contra-indicated.
10008347
c
Renal Impairment
QuestionChoice
Correct - Trimethoprim interferes with folate which is important for foetal central nervous system development. Therefore, it is contraindicated in women in the first trimester of pregnancy.
10008345
a
Pregnancy
QuestionChoice
Incorrect - Trimethoprim is not contraindicated in elderly patients.
10008348
d
The elderly
Concept
Chapter
2693
3887
Antibiotics
Topic
148
Microbiology
14216
A 34-year-old presents to her GP with pain on urination and a frequent urge to pass urine. Her GP suspects she has a urinary tract infection and prescribes trimethoprim.

In which patient group are antifolates, such as trimethoprim, contraindicated?
a