QuestionSBA
QuestionChoice
This patient has neuropathic pain, characterised by a burning sensation, tingling and pain. According to NICE recommendations, there are four first-line medications to control neuropathic pain, which are gabapentin, pregabalin, amitriptyline and duloxetine. Since this patient has had a recent myocardial infarction (MI), amitriptyline is contraindicated, because it could cause arrhythmias. Arrhythmias can be particularly dangerous in patients with a recent MI, as the heart may already be vulnerable and more prone to irregular rhythms.
10025284
e
Amitriptyline
QuestionChoice
This patient has neuropathic pain, characterised by a burning sensation, tingling and pain. According to NICE recommendations, there are four first-line medications to control neuropathic pain: gabapentin, pregabalin, amitriptyline and duloxetine. Tramadol, an opioid, is only recommended as an acute rescue option for short term alleviation of flares. Furthermore, tramadol, like other opioids, can affect the cardiovascular system, leading to changes in heart rate and blood pressure. This is not ideal given her recent recovery from myocardial infarction.
10025282
c
Tramadol
QuestionChoice
This patient has neuropathic pain, characterised by a burning sensation, tingling and pain. According to NICE recommendations, there are four first-line medications to control neuropathic pain: gabapentin, pregabalin, amitriptyline and duloxetine. Naproxen, an NSAID, is more effective at reducing inflammation and relieving pain from inflammatory conditions such as arthritis or musculoskeletal injuries. Neuropathic pain is related to nerve damage and dysfunction, and it typically does not involve inflammation.
10025283
d
Naproxen
QuestionChoice
This patient has neuropathic pain, characterised by a burning sensation, tingling and pain. According to NICE recommendations, there are four first-line medications to control neuropathic pain: gabapentin, pregabalin, amitriptyline and duloxetine. Gabapentin, an anticonvulsant, is commonly used to manage neuropathic pain associated with conditions like MS. It works by stabilising overactive nerve cells and reducing abnormal electrical activity, which can help alleviate symptoms of neuropathic pain.
10025280
a
Gabapentin
QuestionChoice
This patient has neuropathic pain, characterised by a burning sensation, tingling and pain. According to NICE recommendations, there are four first-line medications to control neuropathic pain: gabapentin, pregabalin, amitriptyline and duloxetine. Carbamazepine is a first-line medication only for a specific type of neuropathic pain, trigeminal neuralgia, which is characterised by severe, sharp, shooting facial pain.
10025281
b
Carbamazepine
Concept
Chapter
2693
5827
Treatment of neuropathic pain
Topic
172
Pharmacology of the Nervous System
17454
A 46 year old patient who has a past medical history of relapsing-remitting multiple sclerosis (MS) is experiencing burning, tingling and pain in her hands. This has significantly impacted her day-to-day living. She was recently discharged from hospital following a myocardial infarction.

Which of the following drugs is the most suitable to alleviate this patient's pain?
a