QuestionSBA
QuestionChoice
This is incorrect. Candesartan is an angiotensin receptor blocker (ARB) and works by inhibiting the interaction of angiotensin with its receptor. It therefore has a direct effect on RAAS.
10026437
c
Candesartan
QuestionChoice
This is incorrect. Spironolactone is a potassium-sparing diuretic that works by inhibiting the action of aldosterone. It therefore has a direct effect on RAAS.
10026438
d
Spironolactone
QuestionChoice
This is incorrect. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor and works by reducing angiotensin II production. It therefore has a direct effect on RAAS.
10026436
b
Ramipril
QuestionChoice
This is correct. Indapamide is a thiazide-like diuretic and so inhibits the Na+/Cl- cotransporter in the distal convoluted tubule. This does not involve RAAS.
10026435
a
Indapamide
QuestionChoice
This is incorrect. Aliskiren is a drug used for hypertension that works by inhibiting renin and hence reducing the production of angiotensin and aldosterone. It therefore has a direct effect on RAAS.
10026439
e
Aliskiren
Concept
Chapter
2693
4531
The effect of the renin-angiotensin system on electrolytes
Topic
168
Renal Physiology
17685
Which of the following medications is the only one which does not target the renin-angiotensin-aldosterone system (RAAS)?
a