QuestionSBA
QuestionChoice
This patient has most likely been given the wrong type of blood, which causes IgG antibodies to be produced towards the incompatible blood type, leading to the agglutination of these cells and inflammation.
10023650
a
Type II hypersensitivity reaction
QuestionChoice
There is no type V hypersensitivity reaction, so this option is incorrect.
10023654
e
Type V hypersensitivity reaction
QuestionChoice
This is when an antigen-antibody complex is deposited into the small vasculature, causing an immune response which leads to inflammation. This can cause autoimmunity; an example of a type III hypersensitivity reaction is rheumatoid arthritis.
10023652
c
Type III hypersensitivity reaction
QuestionChoice
An example of this is contact dermatitis. The reactive molecule binds as a hapten to an endogenous protein which is recognised and taken up by Langerhans cells. This causes T helper cells to secrete IFN-γ and cause a pro-inflammatory state within the tissue. This patient is not experiencing this type of reaction.
10023653
d
Type IV hypersensitivity reaction
QuestionChoice
This is when an allergen is picked up by dendritic cells which activate B cells and produce IgE antibodies. These IgE antibodies attach to mast cells and cause them to degranulate, releasing histamine. This patient has experienced a type II, not type I hypersensitivity reaction.
10023651
b
Type I hypersensitivity reaction
Concept
Chapter
2693
4091
Hypersensitivity reactions
Topic
158
Immunology
17128
A 53-year-old male comes into the hospital as he is feeling tired all the time and experiencing occasional dizziness. The doctor performs some blood tests and finds that he has a haemoglobin of 58g/dl. The doctor organises a blood transfusion for this patient as his haemoglobin is low.

However, during the blood transfusion, the patient starts to develop a fever. The doctor on-call thinks this is due to a hypersensitivity reaction.

Which type of hypersensitivity reaction has this patient experienced?
a