QuestionSBA
QuestionChoice
The number of astrocytes in multiple sclerosis often increases as neurons become damaged and destroyed (this is called astrogliosis) however are not responsible for demyelination.
10004553
c
Astrocytes
QuestionChoice
Macrophages have been shown to assemble in their activated forms at sites of neurodegeneration in multiple sclerosis. This is an inflammatory reactive process, not a demyelinating one and there is no loss of macrophages seen.
10004555
e
Macrophages
QuestionChoice
Microglia have been shown to assemble in their activated forms at sites of neurodegeneration in multiple sclerosis. This is an inflammatory reactive process, not a demyelinating one and there is no loss of microglia seen.
10004554
d
Microglia
QuestionChoice
Oligodendrocytes are a type of neuroglial cell responsible for the insulation of axons in the central nervous system. They do this by the creation and maintenance of myelin, which allows the efficient transmission of action potentials. Loss of oligodendrocytes in multiple sclerosis results in demyelination of neuronal axons, so the neurons are unable to conduct action potentials as effectively.
10004551
a
Oligodendrocytes
QuestionChoice
Although neurons can be damaged and destroyed as the disease progresses, this process is not responsible for the characteristic loss of myelin seen in multiple sclerosis.
10004552
b
Neurons
Concept
Chapter
2693
3745
Multiple Sclerosis
Topic
141
Neurology
13457
The loss of which cell type is responsible for the demyelination seen in multiple sclerosis?
a