QuestionSBA
QuestionChoice
This is incorrect. The distal tubules are critically involved in acid-base balance, and while the proximal tubules play a role in reabsorbing bicarbonate, the primary regulation of H+ ion secretion occurs in the distal tubules.
10026093
d
The distal tubules play a minimal role in acid-base balance, with the primary regulation occurring in the proximal tubules
QuestionChoice
This is incorrect. The primary function of the distal tubules is to secrete H+ ions and reabsorb bicarbonate ions, which is the reverse of what this option suggests.
10026094
e
The distal tubules primarily reabsorb H+ ions and excrete bicarbonate ions to maintain acid-base balance
QuestionChoice
This is correct. The distal tubules are crucial for regulating acid-base balance. They secrete H+ ions into the urine and reabsorb bicarbonate ions to help maintain proper pH in the body.
10026090
a
H+ ions are secreted into urine at the distal tubules whilst bicarbonate ions are reabsorbed
QuestionChoice
This is not correct. While the proximal tubules are involved in various processes, including bicarbonate reabsorption, the primary site for H+ ion secretion to regulate acid-base balance is the distal tubules.
10026091
b
H+ ion secretion occurs primarily in the proximal tubules
QuestionChoice
This is incorrect. Impaired H+ ion secretion in the distal tubules would lead to metabolic acidosis, not metabolic alkalosis.
10026092
c
Impaired H+ ion secretion in the distal tubules contributes to metabolic alkalosis
Concept
Chapter
2693
5876
Hydrogen ion secretion at the distal tubule
Topic
168
Renal Physiology
17616
A 40 year old man presents to the Emergency Department with complaints of extreme fatigue, muscle weakness and confusion. He has a history of chronic kidney disease and type 2 diabetes. Blood tests reveal severe metabolic acidosis.

Which of the following describes the renal mechanism by which acid-balance status is usually maintained?
a