QuestionSBA
QuestionChoice
Although a SAH could present with weakness, given the patient history and antibody findings, the likely diagnosis is GBS.
10001601
e
Subarachnoid haemorrhage (SAH)
QuestionChoice
Miller-Fisher Syndrome (MFS) is one of the rare forms of a spectrum of Guillain-Barré syndrome (GBS). In contrast to GBS, which typically affects the lower body first (as seen in this case), MFS tends to affect the upper body first. Anti-ganglioside antibodies are associated with several immunologically mediated peripheral neuropathies e.g. anti-GM1 (IgM) with multifocal motor neuropathy, GQ1b (IgG) with Miller-Fisher syndrome, and GM1 (IgG) with Guillain-Barre syndrome.
10001598
b
Miller-Fisher Syndrome (MFS)
QuestionChoice
Although a TIA could present with weakness, given the patient history and antibody findings, the likely diagnosis is GBS.
10001599
c
Transient ischaemic attack (TIA)
QuestionChoice
Infection with Campylobacter jejuni, commonly infecting individuals who consume undercooked poultry, is one of the most common causes of Guillian-Barre syndrome (GBS). Given this patient's holiday history and anti-ganglioside antibodies, GBS is the correct diagnosis. Anti-ganglioside antibodies are associated with several immunologically mediated peripheral neuropathies e.g. anti-GM1 (IgM) with multifocal motor neuropathy, GQ1b (IgG) with Miller-Fisher syndrome, and GM1 (IgG) with Guillain-Barre syndrome.
10001597
a
Guillian-Barre syndrome (GBS)
QuestionChoice
Although a stroke could present with weakness, given the patient's history and antibody findings, the likely diagnosis is GBS.
10001600
d
Ischaemic stroke
Concept
Chapter
2693
3947
Guillian-Barre Syndrome
Topic
141
Neurology
12866
A 27-year-old man presents to ED with leg weakness having travelled back from meeting family in America two weeks ago. He had several outdoor parties and barbecues whilst away, but since coming home he has not felt quite himself. Investigations have shown the presence of anti-ganglioside antibodies.

What is the most likely diagnosis given his history and investigation findings?
a