QuestionSBA
QuestionChoice
Although hypothyroidism may also present with weight gain and irregular periods, the presence of hirsutism points towards a diagnosis of PCOS. Whilst PCOS may sometimes be associated with some derangement in thyroid hormones, serum androgen levels are more specific in confirming the diagnosis.
10002270
d
Thyroid function tests
QuestionChoice
This patient is presenting with signs and symptoms of polycystic ovarian syndrome (PCOS). In PCOS, the follicles which contain maturing eggs are often unable to release an egg, leading to irregular periods and potential infertility. PCOS is associated with high levels of serum androgens (e.g. testosterone), which can lead to hirsutism. Diagnosis of PCOS can be difficult but is often based on measuring serum androgen levels, measuring FSH/LH levels, and performing a transvaginal ultrasound scan to assess the ovaries for the presence of multiple follicles.
10002267
a
Serum androgen levels
QuestionChoice
Whilst PCOS may be associated with some derangement in insulin levels, serum androgen levels would be more specific in confirming the diagnosis.
10002271
e
Serum insulin levels
QuestionChoice
Serum hCG levels may be useful for assessing whether a patient is pregnant. However, the presence of hirsutism, as well as the history of infertility, makes a diagnosis of PCOS more likely.
10002268
b
Serum human chorionic gonadotrophin (hCG) levels
QuestionChoice
Transvaginal ultrasound scans (rather than CT scans) are used to assess the ovaries for multiple follicles in PCOS.
10002269
c
CT scan of ovaries
Concept
Chapter
2693
4025
PCOS
Topic
175
Reproductive Physiology
13000
A 34-year-old female presents to General Practice with irregular periods, weight gain and difficulty conceiving despite trying for over one year. On examination, she is noted to have excessive hair growth around her face and upper back.

Which of the following investigations would be most useful in confirming this woman's diagnosis?
a