QuestionSBA
QuestionChoice
This is correct. The Na+/K+ ATPase actively pumps 3 Na+ ions out of the cell and 2 K+ ions into the cell. The other channels listed are involved in other aspects of ion transport in the nephron but do not transport sodium into the interstitium from the thick ascending limb.
10026220
a
Na+/K+ ATPase
QuestionChoice
This is incorrect. These are ATP-dependent potassium channels that move potassium out of cells. They are involved in potassium recycling in the thick ascending limb and potassium secretion in the collecting duct. They do not transport sodium from the cell into the interstitium.
10026224
e
Renal outer medullary potassium (ROMK) channels
QuestionChoice
This is incorrect. Chloride channels are important for stabilisation of cell membrane potential but do not transport sodium.
10026223
d
Chloride (Cl-) channels
QuestionChoice
This is incorrect. These channels facilitate the movement of water across cell membranes. They do not transport sodium.
10026221
b
Aquaporin-1 (AQP-1) channels
QuestionChoice
This is incorrect. These channels are located on the apical membrane of epithelial cells and facilitate the reabsorption of sodium ions across the apical membrane of epithelial cells in the distal nephron.
10026222
c
Epithelial Na+ (eNaC) channels
Concept
Chapter
2693
4242
Salt Transport in the loop of Henle
Topic
168
Renal Physiology
17642
A 45 year old male with a history of chronic kidney disease is admitted to the medical ward with deranged electrolyte levels. He is keen to learn more about the role of the kidney in regulating these electrolytes.

In the thick ascending limb of the loop of Henle, which of the following channels is responsible for the transport of sodium from the cell into the interstitium?
a