QuestionSBA
QuestionChoice
In most cases, oral medications do not take effect until they reach the stomach and are absorbed into the blood stream. Modified release preparations are designed to have a longer duration of action than regular oral morphine, however they must still be absorbed from the gastro-intestinal tract and reach the bloodstream before taking effect.
10007017
b
Oral morphine (modified release)
QuestionChoice
Transdermal medications, that are applied to the external surface of the skin, generally work for extended periods of time and do not begin action as quickly as intravenous drugs.
10007020
e
Transdermal fentanyl patch
QuestionChoice
This question tests knowledge of routes of administration. Intravenous medications are injected directly into the bloodstream, bypassing first pass metabolism in the liver and bowel. It is therefore extremely fast acting.
10007016
a
Intravenous tramadol
QuestionChoice
Topical ibuprofen gel must penetrate the skin before it is able to take effect. It therefore takes longer to work than intravenous medications.
10007019
d
Topical ibuprofen gel
QuestionChoice
In most cases, oral medications do not take effect until they reach the stomach and are absorbed into the blood stream. Oral morphine must be absorbed from the gastro-intestinal tract and reach the bloodstream before taking effect.
10007018
c
Oral morphine
Concept
Chapter
2693
4559
Routes of administration
Topic
166
General pharmacological concepts
13950
A 44-year-old is seen in the emergency department with severe pain due to a fracture of his right humerus.  He requests some analgesia through the fastest-acting means available.

Which of the following routes of administration enables the drug to work most quickly?
a