QuestionSBA
QuestionChoice
Antibiotics like Metronidazole work by damaging DNA. Clindamycin does not work in this way but instead works by inhibiting protein synthesis.
10007529
d
Damages DNA
QuestionChoice
This is the mechanism of action of sulphonamides and trimethoprim. Clindamycin does not work in this way but instead works by inhibiting protein synthesis.
10007528
c
Inhibits folic acid formation
QuestionChoice
Antibiotics like Rifampicin work by inhibiting the synthesis of RNA. Clindamycin does not work in this way but instead works by inhibiting protein synthesis.
10007530
e
Inhibits RNA synthesis
QuestionChoice
There are various classes of antibiotics that work by inhibiting cell wall formation. Some interrupt peptidoglycan cross-linking (penicillin and cephalosporins) and others inhibit peptidoglycan synthesis (glycopeptides like vancomycin). Clindamycin does not work in this way but instead works by inhibiting protein synthesis.
10007527
b
Inhibits cell wall formation
QuestionChoice
This is the correct answer. Clindamycin inhibits protein synthesis by acting on the ribosome. Other antibiotics that act in the same way include: macrolides, aminoglycosides and tetracycline.
10007526
a
Inhibits protein synthesis
Concept
Chapter
2693
3887
Antibiotics
Topic
148
Microbiology
14052
A 50-year-old male presents to the GP with a red, painful right shin that began a week ago. He reports feeling unwell with a high temperature for the past 3 days.  The GP suspects cellulitis and the patient is treated with a course of clindamycin.

Which of the following correctly describes the mechanism of action of clindamycin?
a