QuestionSBA
QuestionChoice
This is one of the two BRCA genes that is linked to familial forms of breast cancer and ovarian cancer.
10004170
e
BRCA1 gene
QuestionChoice
This is a gene which is formed by the exchange of genetic information between chromosome 9 and chromosome 22. This forms a Philadelphia chromosome which is often found in chronic myeloid leukaemia.
10004169
d
BCR-ABL gene
QuestionChoice
This patient is presenting with a likely renal mass, specifically Wilm's tumour. This is a type of kidney cancer that typically presents in children below the age of 3. Specifically mutations in the WT1 gene, which is a tumour suppressor gene, cause Wilm's tumour.
10004166
a
WT1 gene
QuestionChoice
This is a tumour suppressor gene which is linked to the formation of retinoblastoma, a type of cancer in the eye found in young children.
10004167
b
RB1 gene
QuestionChoice
This is a DNA mismatch repair gene. It is one of the genes which is linked to hereditary nonpolyposis colorectal cancer (HNPCC). This is the most common genetic form of colorectal carcinoma.
10004168
c
MSH2 gene
Concept
Chapter
2693
4012
Renal Cancer
Topic
143
Urology
13380
A 2-year-old girl is brought into the GP surgery by her parents. They have noticed blood in her urine and describe left flank pain. Upon palpation of the left flank, a large mass is felt.

Which of the following genes is most likely responsible for this presentation?
a