QuestionQA
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

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2854
Drug Calculations
Topic
76
Obstetrics and Gynaecology
Total mass (g) of magnesium sulphate required = 28g

10% 10mL ampoule
= 10g in 100mL
= 1g in 10mL ampoule

Total 10% 10mL ampoule required for 28g of magnesium sulphate
= 28 10% 10mL ampoules
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QuestionQAAnswer
28
10% 10mL ampoules
A 30-week pregnant woman is admitted to the Emergency Department with seizure. Her blood test confirmed eclampsia and she is treated with a short course of magnesium before being sent to theatre for the delivery of her baby.

Her IV medication has been prescribed as below:

* IV Magnesium 4g 5-15min.
* IV Magnesium 24g for 24 hours.


Magnesium sulphate is available as 10% solution for injection in 10mL ampoules.
Weight 75kg.

How many ampoules of magnesium sulphate solution is required in total for the prescribed medication above?
