QuestionSBA
QuestionChoice
Antibiotics like metronidazole work by damaging DNA. Statins do not work in this way, but instead by inhibiting HMG-CoA reductase.
10025004
e
Damage DNA
QuestionChoice
This is the correct answer. Statins inhibit HMG-CoA reductase which, in turn, reduces the amount of cholesterol made by the liver (and also helps the liver remove cholesterol that has already been formed and deposited in the blood).
10025000
a
Inhibit HMG-CoA reductase
QuestionChoice
This is the mechanism of action of warfarin, not statins. Statins inhibit HMG-CoA reductase, which reduces the amount of cholesterol in the blood.
10025001
b
Inhibit vitamin K epoxide reductase complex 1
QuestionChoice
Antibiotics like macrolides and tetracycline work to inhibit protein synthesis. Statins instead work by inhibiting HMG-CoA reductase.
10025003
d
Inhibit protein synthesis
QuestionChoice
This is the mechanism of action of sulphonamides and trimethoprim. Statins do not work in this way, but instead by inhibiting HMG-CoA reductase.
10025002
c
Inhibit folic acid formation
Concept
Chapter
2693
5817
Statins
Topic
166
General pharmacological concepts
17398
A 45-year-old male found to have a QRESEARCH cardiovasclar risk algorithm (QRISK) score that is over 10%. His GP recommends he begins a medication called atorvastatin.

Which of the following correctly descibes the mechanism of action of statins?
a