QuestionSBA
QuestionChoice
This answer is incorrect. Alpha-2 delta-2 is the structure of haemoglobin A2 (HbA2) which constitutes around 2.5% of haemoglobin in an adult.
10007274
d
Alpha-2 delta-2
QuestionChoice
This answer is incorrect. This is not a recognised structure of haemoglobin.
10007275
e
Alpha-1 beta-3
QuestionChoice
This answer is incorrect. Alpha-2 beta-2 is the structure of adult haemoglobin. The most prevalent form of haemoglobin in a neonate is foetal haemoglobin (alpha-2 gamma-2). From 3-6 months after birth, foetal haemoglobin is gradually replaced by adult haemoglobin.
10007272
b
Alpha-2 beta-2
QuestionChoice
This answer is incorrect. Zeta-2 epsilon-2 is the structure of Gower-1 haemoglobin, which is the first type of haemoglobin produced during development in the embryonic yolk sac. After 6 weeks, foetal haemoglobin (alpha-2 gamma-2) replaces Gower-1 haemoglobin.
10007273
c
Zeta-2 epsilon-2
QuestionChoice
This answer is correct. Alpha-2 gamma-2 is the structure of foetal haemoglobin which is the most prevalent form of haemoglobin in a neonate. The production of foetal haemoglobin begins in the sixth week of pregnancy and stops two to four months after birth.
10007271
a
Alpha-2 gamma-2
Concept
Chapter
2693
4583
Haemoglobin
Topic
193
Haematological Science
14001
A newborn baby undergoes blood spot (heel prick) testing as part of their routine newborn investigations to screen for inherited conditions including sickle cell disease. The results are normal.

Which of the following globin chains make up the most prevalent form of haemoglobin in a neonate?
a