QuestionSBA
QuestionChoice
If patients have forgotten to take a dose, they should take the missed dose as soon as they remember. However, if it is almost time for them to take the next dose, they should skip the missed dose and take the next dose as usual. They should not take a double dose to make up the missed dose
34139
e
If he forgets to take a dose of olanzapine, he should take a double dose to compensate for the forgotten dose
QuestionChoice
Agranulocytosis is an uncommon but potentially fatal side effect of olanzapine
34138
d
Agranulocytosis is a common side effect of olanzapine
QuestionChoice
It is mandatory for all the patients taking clozapine, not olanzapine, to be registered with the patient monitoring service. The service provides centralised monitoring of leucocyte and neutrophil counts in order to manage the risk of agranulocytosis associated with clozapine
34136
b
He will be registered with the patient monitoring service set up by the drug manufacturer
QuestionChoice
Increased appetite leading to weight gain is a common side effect of olanzapine. Hence, it is recommended to measure blood lipids and weight at baseline, every 3 months for the first year and then yearly for all the patients taking olanzapine
34135
a
Olanzapine can increase appetite and lead to weight gain
QuestionChoice
Olanzapine is linked to eosinophilia rather than low eosinophil counts
34137
c
Olanzapine can cause low eosinophil count
QuestionComment
Why wouldn't you warn about fatal consequence of agranulocytosis?
6919
QuestionComment
Agranulocytosis is more relavent to Clozapine than Olanzapine 
17119
User
subscriber
Serpiginous Serotonin
User
subscriber
S 
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

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2771
Atypical antipsychotic
Topic
90
Psychiatry
6838
Case presentation: A 30-year-old man attends the psychiatric clinic for his medication review. He was diagnosed with schizophrenia three month ago and has been taking anti-psychotic and cognitive behavioural therapy. His symptoms have improved but he wishes to stop taking the medication because it is giving him continuous spasms and muscle contractions that greatly affect his daily living.  

DH: Chlorpromazine hydrochloride 25mg PO thrice daily
SH: Works as a carpenter, lives alone
The patient is advised to switch his current treatment regime to olanzapine 10mg PO daily under the supervision of his psychiatrist.

Question: Select the most important information that should be provided for this patient.
a