QuestionSBA
QuestionChoice
Yes, this is the correct answer. Haemophilia A is the deficiency of factor VIII in the clotting cascade. This condition is associated with a prolonged aPTT, while other coagulation tests are within the normal range. Symptoms include easy bruising and bleeding.
10007910
a
Haemophilia A
QuestionChoice
No, this is not the correct answer. Factor V Leiden conveys thrombophilia, where there is an increased predisposition to thrombosis, rather than easy bruising.
10007914
e
Factor V Leiden
QuestionChoice
No, this is not the correct answer. Haemolytic uraemic syndrome is associated with a low platelet count. Individuals also present with renal failure.
10007913
d
Haemolytic uraemic syndrome
QuestionChoice
No, this is not the correct answer. Antiphospholipid syndrome conveys thrombophilia, where there is an increased predisposition to thrombosis, rather than easy bruising.
10007911
b
Antiphospholipid syndrome
QuestionChoice
No, this is not the correct answer. Von Willebrand's disease is associated with a prolonged aPTT and a prolonged bleeding time.
10007912
c
von Willebrand's disease
Concept
Chapter
2693
4630
Haemophilias
Topic
193
Haematological Science
14129
A 36-month-old boy is attends the GP surgery with his mother, who is concerned that his skin bruises very easily. Her father also has this problem and was diagnosed with a haematological condition as a child, but she cannot remember what it is called.


The child is otherwise fit and well, with no known medical conditions and no regular medications.


Investigation results are as follows:


||||
|---------------------------|:-------:|--------------------|
|Platelets|197x10<sup>9</sup>/L|150 - 400|
|Activated Partial Thromboplastin Time (APTT)|59  seconds|22 - 41|
|International Normalised Ratio (INR)|1.0|1.0|
|Bleeding Time|5 minutes|< 10|

Which of the followings is the most likely underlying diagnosis?
a