QuestionSBA
QuestionChoice
This is incorrect. This is the mechanism of action of phosphodiesterase inhibitors such as milrinone.
10026301
b
Inhibition of phosphodiesterase
QuestionChoice
This is correct. Digoxin inhibits the Na+/K+ ATPase which prevents Na+ efflux from the cell, causing a rise in intracellular Na+. This lowers the Na+ gradient across the cell which makes the Na+/Ca2+ exchanger less effective, preventing Ca2+ efflux. This, therefore increases the Ca2+ levels in the cell, increasing contractility.
10026300
a
Inhibition of the Na+/K+ ATPase
QuestionChoice
This is incorrect. This is the mechanism of action of beta-blockers such as bisoprolol.
10026303
d
Inhibition of beta-adrenergic receptors
QuestionChoice
This is incorrect. This is the mechanism of action of ivabradine.
10026302
c
Inhibition of the funny currents
QuestionChoice
This is incorrect. This is the mechanism of action of angiotensin II receptor blockers (ARBs) such as losartan.
10026304
e
Inhibition of angiotensin II receptor
Concept
Chapter
2693
4552
Digoxin
Topic
169
Cardiovascular pharmacology
17658
What is the mechanism of action of digoxin?
a