QuestionSBA
QuestionChoice
Marfan syndrome is a genetic connective tissue disorder which usually occurs due to a mutation in the fibrillin-1 gene. There is currently no known link between Marfan syndrome and the development of Alzheimer's disease.
10002474
c
Marfan syndrome
QuestionChoice
Motor neurone disease involves the destruction of motor neurones in the spinal ventral horns, brainstem motor nuclei, and the motor cortex. There is currently no known link between motor neurone disease and the development of Alzheimer's disease.
10002475
d
Motor neurone disease
QuestionChoice
Mutations in the LRRK 2 gene are more commonly seen in Parkinson's disease, as opposed to Alzheimer's disease.
10002473
b
Mutation in LRRK 2 gene
QuestionChoice
Current research indicates that Alzheimer's disease is far more common in females than males.
10002476
e
Male sex
QuestionChoice
Down's syndrome is an important risk factor in the development of Alzheimer's disease, with around 30% of Down's syndrome individuals developing dementia by their 50s. One of the reasons for this is that chromosome 21 carries the amyloid precursor protein (APP) gene, which codes for amyloid protein development and deposition. In Down's syndrome, the extra chromosome 21 can result in excessive amyloid protein formation, leading to Alzheimer's disease.
10002472
a
Down's syndrome
Concept
Chapter
2693
4042
Alzheimer's disease
Topic
191
Geriatrics
13041
Which of the following options is a risk factor for the development of Alzheimer's disease?
a