QuestionSBA
QuestionChoice
Co-amoxiclav is not known to cause auditory nerve damage. On the other hand, streptomycin is associated with foetal ototoxicity
34278
d
Auditory nerve damage
QuestionChoice
Co-amoxiclav is not known to discolour the teeth. On the other hand, tetracycline and doxycycline are associated with bone and teeth discolouration
34277
c
Teeth discolouration
QuestionChoice
Co-amoxiclav is not known to cause hepatic failure in neonates
34279
e
Hepatic failure
QuestionChoice
Co-amoxiclav is associated with an increased risk of necrotising enterocolitis in neonates
34275
a
Necrotising enterocolitis
QuestionChoice
Co-amoxiclav is not known to cause cholestatic jaundice in neonates
34276
b
Cholestatic jaundice
QuestionComment
Weird q as necrotising enterocolitis is only really a risk when in PPROM. Otherwise BNF says not harmful 
18079
QuestionComment
Yep that's why I didn't choose it either
36897
User
subscriber
Epidermis Abdominal
User
subscriber
Monoclonal Polyps
QuestionComment
is this the same as pseudomembranous enterocolitis?
61862
QuestionComment
No, that's caused by Clostridium Difficile
62335
User
subscriber
Uremic Tanoy
User
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SuturedAndBooted
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

2618
2798
Co-amoxiclav side effects
Topic
66
Obstetrics & Gynaecology
6866
Case presentation: A 34-year-old pregnant woman is admitted to hospital for community-acquired pneumonia. She is a primigravida and is currently 22 weeks into her pregnancy. She has hyperemesis gravidarum and is not able to tolerate oral medication well.  

Observations: Temperature 37.5, Respiratory rate 32, Blood pressure 88/64, Heart rate 76
On examination: Coarse crackles at left lung base, normal antenatal examination
The junior doctor would like to discuss with the obstetric consultant commencing treatment with Co-amoxiclav 1.2 g TDS because the junior doctor is concerned that co-amoxiclav may increase the risk of a particular neonatal condition.

Question: Select the neonatal condition that is most likely to be caused by Co-amoxiclav
a