QuestionQA
QuestionComment
this is an insane question ngl
60718
QuestionComment
no cos like how are we supposed to do it in that much time 
61867
User
subscriber
Intubation Serotonin
User
subscriber
Gastro Womb
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

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Calculation of infusion rate
Topic
66
Obstetrics & Gynaecology
- Dose of labetalol given at 10mg/hour: 10mg/hour x 0.5 hours = 5mg
- Dose of labetalol given at 20mg/hour: 20mg/hour x 0.5 hours = 10mg
- Dose of labetalol given at 40mg/hour: 40mg/hour x 0.5 hours = 20mg
- Dose of labetalol given at 80mg/hour: 80mg/hour x 0.25 hours = 20mg

Total dose of labetalol given: 5mg + 10mg + 20mg + 20mg = 55mg

10mg given for 30 minutes (0.5 hours).
20mg given for 30 minutes (0.5 hours).
40mg given for 30 minutes (0.5 hours).
80mg given for 15 minutes (0.25 hours).

1.75 hours total. 55/1.75 = 31.4285714

To one decimal place = 31.4mg/hr
10099
QuestionQAAnswer
31.4
mg/hour
 

Case Presentation:

A 34-year-old patient with hypertension in pregnancy is prescribed labetalol by intravenous infusion.

She was initially given 10mg/hour, which was increased to 20mg/hour after 30 minutes, this was continued for 30 minutes and then increased to 40mg/hour. After another 30 minutes this was finally increased to 80mg/hour.

This continued for 15 minutes, after which the response was satisfactory and the infusion was stopped.

What is the average hourly rate at which this infusion has been given? Give your answer to one decimal place.