QuestionSBA
QuestionChoice
This enzyme catalyses the splitting of fructose-1,6-bisphosphate into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. This is the step in glycolysis after the main rate-limiting step catalysed by phosphofructokinase and has little regulatory effect on the glycolysis rate.
10004498
c
Fructose-bisphosphate aldolase
QuestionChoice
This enzyme decarboxylates oxalosuccinate to A-ketoglutarate and CO2. This reaction is the main rate-limiting step of the citric acid cycle.
10004500
e
Isocitrate dehydrogenase
QuestionChoice
This catalyses the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate. This reaction is the rate-limiting step in gluconeogenesis, not glycolysis.
10004497
b
Fructose 1,6-bisphosphatase
QuestionChoice
This catalyses the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. It is allosterically activated by AMP and inhibited by ATP, allowing the rate of glycolysis to be altered according to the energetic demands of the cell.
10004496
a
Phosphofructokinase-1
QuestionChoice
Pyruvate dehydrogenase is not involved in glycolysis. This decarboxylates pyruvate to generate acetyl-CoA, the starting point for the citric acid cycle.
10004499
d
Pyruvate dehydrogenase
Concept
Chapter
2693
3941
Glycolysis
Topic
180
Biochemistry
13446
The activity of which enzyme has the greatest effect on the rate of glycolysis?
a