QuestionSBA
QuestionChoice
Butterfly rash (aka malar rash) is a sign most commonly associated with systemic lupus erythematosus. Although facial skin sclerosis can occur in limited systemic sclerosis, it does not manifest as a butterfly rash.
10000473
c
Butterfly rash
QuestionChoice
Inflammatory arthritis is an extremely uncommon presentation of systemic sclerosis and may instead suggest overlap with another autoimmune condition (or indeed a different diagnosis altogether). Although patients may experience arthralgia, an inflammatory arthritis is unlikely in limited systemic sclerosis.
10000474
d
Inflammatory joint pain
QuestionChoice
This patient suffers from limited systemic sclerosis, as indicated by the presence of Raynaud's phenomenon as well as sclerotic skin changes limited to the face and distal limbs (i.e. below elbow/knee). Oesophageal dysmotility is a very common symptom of limited systemic sclerosis and typically manifests as heartburn, dysphagia, and gastro-oesophageal reflux. Patients with limited systemic sclerosis may also develop telangiectasia, calcifications, and sclerodactyly. Late in the disease patients may develop interstitial lung disease and pulmonary artery hypertension.
10000471
a
Heartburn
QuestionChoice
Jaundice is not a typical symptom of limited systemic sclerosis. Although primary biliary cirrhosis (chronic inflammatory destruction of hepatic bile ducts) can uncommonly occur in diffuse systemic sclerosis, it does not occur in limited disease.
10000472
b
Jaundice
QuestionChoice
Dry eyes are a classical symptom of Sjögren's syndrome. Dry eyes and mouth are two clinical hallmarks of this autoimmune disease but would not be found in systemic sclerosis (at least not without the presence of disease overlap).
10000475
e
Dry eyes
Concept
Chapter
2693
3771
Systemic sclerosis
Topic
146
Rheumatology
12641
A 39-year-old female presents to the clinic. She reports a 2-month history of her fingers turning blue in the cold as well as some skin thickening in her hands. On examination, you identify the presence of digital ulcers as well as thickened, sclerotic skin that involves the hands and wrists bilaterally. There is also some sclerotic skin on her face.

Which of the following symptoms is the patient most likely to also experience?
a