QuestionSBA
QuestionChoice
Given the BNF advises stopping statin therapy if serum transaminases are greater than 3 times the upper limit of the reference range it would be unwise to continue the statin
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b
Continue atorvastatin 20mg
QuestionChoice
The BNF advises if serum transaminases are greater than 3 times the upper limit of the reference range then statin therapy should be discontinued.
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a
Stop atorvastatin 20mg
QuestionChoice
There is no suggestion that the patient is acutely unwell or needs secondary care input, despite the abnormal blood test results.

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c
Admit to hospital
QuestionChoice
This is incorrect as statin therapy should be discontinued.
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d
Increase to atorvastatin 80mg
QuestionChoice
Although other classes of lipid lowering drugs may be considered as a result, the most important action is to stop this patient's atorvastatin, in light of the recent blood test results.
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e
Add ezetimibe
Concept
Chapter
2693
6087
Statins
Topic
329
General Practice
18115
Case Presentation: A 59-year-old man attends the GP to discuss his most recent blood test results. He was commenced on atorvastatin 20mg PO ON for primary prevention of cardiovascular events. 


 **Investigations**
ALT before treatment: 40 (10 - 50 IU/L)
ALT 3 weeks later: 163 (10 - 50 IU/L)


Question: Select the most appropriate decision option with regard to the atorvastatin based on these data.
a