QuestionSBA
QuestionChoice
Atopic dermatitis would present with dry skin and areas of erythematous, poorly demarcated itchy patches. It typically affects the flexural regions, such as the antecubital and popliteal fossas.
10003714
d
Atopic dermatitis
QuestionChoice
This patient is experiencing blistering of the skin which is Nikolsky sign positive and oral mucosa ulceration which points toward a diagnosis of pemphigus vulgaris. This is supported by the biopsy and immunofluorescence showing IgG auto-antibody deposits within the epidermis.
10003711
a
Pemphigus Vulgaris
QuestionChoice
Bullous pemphigoid would present with deep, tense blisters which are Nikolsky sign negative. There would also not be any oral mucosa involvement. The biopsy and immunofluorescence would show IgG auto-antibodies deposited on the basement membrane.
10003712
b
Bullous Pemphigoid
QuestionChoice
Patients with chronic plaque psoriasis have symmetrical plaques on extensor surfaces (elbows and knees, scalp, lower back) which are itchy, erythematous and well-demarcated. They do not have blistering.
10003713
c
Chronic plaque psoriasis
QuestionChoice
This would present with pruritic papulovesicular lesions over the legs, but there is no blistering or peeling. It would be Nikolsky sign negative as well. This diagnosis is commonly linked to Coeliac disease.
10003715
e
Dermatits herpetiformis
Concept
Chapter
2693
3916
pemphigus and pemphigoid
Topic
144
Dermatology
13289
A 41-year-old woman presents to the Dermatology clinic with peeling blistering skin over both her legs.

On examination, the top layers of the skin seem to lift away when pressure is applied, and there are signs of oral mucosa ulceration. She has no significant past medical history or family history. A biopsy + immunofluorescence shows deposition of IgG auto-antibodies within the epidermis.

What is the most likely diagnosis?
a