QuestionSBA
QuestionChoice
Iron is crucial for the synthesis of haemoglobin in red blood cells. When iron is lacking, the critical haemoglobin concentration is not achieved causing the red blood cells to look smaller than they should do.
10005926
a
Iron deficiency anaemia
QuestionChoice
In sickle cell disease, red blood cells formed are an unusual shape and so not transfer oxygen as efficiently and do not live as long as normal healthy red blood cells.

This results in a normocytic anaemia as there is just a reduced number of red blood cells with normal MCV.
10005930
e
Sickle cell disease
QuestionChoice
This is an inherited condition that results in the formation of faulty haemaglobin that doesn't function normally.

This does result in microcytic anaemia similarly to iron defiency but is not as common.
10005928
c
Thalassaemia
QuestionChoice
Folate plays a role in the synthesis of DNA and maintanence of normal erythropoiesis.

Similarly to vitamin B12,abnormal cells called megaloblasts are formed that do not divide and mature to healthy red blood cells.

This causes a macrocytic anaemia.
10005929
d
Folate deficiency
QuestionChoice
Vitamin B12 helps synthesise DNA and plays a crucial role in the formation of mature red blood cells.

When there is a lack of vitamin B12, abnormal cells called megaloblasts are formed that do not divide and mature to healthy red blood cells.

This causes a macrocytic anaemia
10005927
b
Vitamin B12 deficiency
Concept
Chapter
2693
4458
Iron deficiency anaemia
Topic
162
General practice
13732
A 69 year old man is diagnosed with microcytic anaemia. This is determined by the low haemaglobin count and low mean corpuscular volume (MCV).

What is the most common cause of this finding?
a