QuestionSBA
QuestionChoice
Nicorandil is used as a vasodilatory drug in the treatment of angina. It does not cause hyperkalaemia but can, however, have a range of other side effects including: headaches, flushing, and skin and eye ulceration.
10007647
b
Nicorandil
QuestionChoice
ACE inhibitors work by inhibiting the conversion of angiotensin I to angiotensin II, preventing the secretion of aldosterone. Aldosterone usually acts to cause sodium reabsorption and consequently, secretion of potassium into the urine. Inhibition of this process through an ACE inhibitor can therefore lead to hyperkalaemia in some patients. Other side effects of ACE inhibitors to be aware of include: cough, angioedema, and first-dose hypotension.
10007646
a
Ramipril
QuestionChoice
Statins work by inhibiting the actions of HMG-CoA reductase in the liver, which is an enzyme involved in cholesterol synthesis. Statins do not commonly cause hyperkalaemia. However, they can cause myopathy, and liver impairment and they can increase the risk of intracerebral haemorrhage in some patients.
10007650
e
Atorvastatin
QuestionChoice
Loop diuretics work by inhibiting the Na-K-Cl cotransporter in the loop of Henle, which reduces the absorption of NaCl. This means that loop diuretics cause hypokalaemia, not hyperkalaemia.
10007648
c
Furosemide
QuestionChoice
Beta-blockers such as propranolol can cause a number of side effects including bronchospasm, fatigue, sleep disturbances, and erectile dysfunction. They do not commonly cause hyperkalaemia.
10007649
d
Propranolol
Concept
Chapter
2693
4614
ACE-inhibitors
Topic
188
Renal Pharmacology
14076
A 59-year-old male is found to have hyperkalaemia on a routine blood test. He has a past medical history of type 2 diabetes mellitus, hypertension and generalized anxiety disorder.

Which of the following medications is most likely to be causing his hyperkalaemia?
a