QuestionSBA
QuestionChoice
This is incorrect. Whilst mannitol does increase the plasma osmolality, this draws fluid out of the intracellular space and into the interstitium and plasma.
10026367
c
It increases the plasma osmolality to draw fluid out of the interstitial space
QuestionChoice
This is correct. Mannitol is a sugar alcohol which sits in the extracellular space and increases the osmolality. This pulls fluid out of the intracellular space down a water potential gradient and hence helps reduce cerebral oedema.
10026365
a
It increases the plasma osmolality to draw fluid out of the intracellular space
QuestionChoice
This is incorrect. This describes the mechanism of action of how dexamethasone reduces cerebral oedema. Mannitol is a sugar alcohol which sits in the extracellular space and increases the osmolality. This pulls fluid out of the intracellular space down a water potential gradient and hence helps reduce cerebral oedema.
10026369
e
It reduces the permeability of capillaries in the brain to prevent fluid leaking out
QuestionChoice
This is incorrect. Whilst mannitol does draw fluid out of the intracellular space, it does this by increasing the plasma osmolality, not osmolarity.
10026366
b
It increases the plasma osmolarity to draw fluid out of the intracellular space
QuestionChoice
This is incorrect. Mannitol is a sugar alcohol which sits in the extracellular space and increases the osmolality. This pulls fluid out of the intracellular space down a water potential gradient and hence helps reduce cerebral oedema.
10026368
d
It increases the plasma osmolarity to draw fluid out of the interstitial space
Concept
Chapter
2693
5889
Osmolality vs Osmolarity
Topic
181
Structure and Function of Cells
17671
What is the mechanism through which mannitol is used to treat cerebral oedema?
a