QuestionSBA
QuestionChoice
There is currently no indication for steroid medications in the medical management of Alzheimer's disease.
10002471
e
Prednisolone
QuestionChoice
Riluzole is a medication option available for the treatment of motor neurone disease, as opposed to Alzheimer's disease. This would typically present with muscle wasting, fasciculations, and difficulties with mobility.
10002470
d
Riluzole
QuestionChoice
Levodopa is usually the first-line medication for Parkinson's disease, as opposed to Alzheimer's disease. This would classically present with bradykinesia, resting tremor and increased rigidity.
10002469
c
Levodopa
QuestionChoice
This patient is presenting with symptoms of Alzheimer's disease, corroborated by the cerebral atrophy seen on the CT scan. Donepezil is an acetylcholinesterase inhibitor which is usually used first-line to improve symptoms in mild-moderate Alzheimer's disease.
10002467
a
Donepezil
QuestionChoice
Memantine is an NMDA receptor antagonist which is typically used in the later stages of Alzheimer's disease, or if acetylcholinesterase inhibitors are not deemed suitable for first-line management.
10002468
b
Memantine
Concept
Chapter
2693
4042
Alzheimer's disease
Topic
191
Geriatrics
13040
An 84-year-old female presents to the neurology clinic with worsening memory, difficulty following instructions, and feeling more confused than usual. Her husband mentions that these symptoms have been ongoing for the past few months and have gradually been getting worse. The patient has a past medical history of hypertension, for which she takes amlodipine and ramipril. A CT brain scan is conducted which reveals cerebral atrophy and enlargement of the cortical sulci.

Given the most likely diagnosis, what is the best first-line medical therapy for this patient?
a