QuestionSBA
QuestionChoice
This is required in early-phase LTP before late-phase LTP occurs. Activation of NMDA receptors allows calcium influx. NMDA receptors are activated once a post-synaptic neuron is already depolarised.
10000753
c
Activation of NMDA receptors in the post-synaptic neuron
QuestionChoice
Nitric oxide diffuses into the presynaptic terminal to cause more glutamate to be released.
10000755
e
Nitric oxide signalling
QuestionChoice
This is required in early-phase LTP before late-phase LTP occurs. These changes result in more excitatory post-synaptic potentials (EPSPs), enhanching neuron depolarisation.
10000752
b
Phosphorylation and insertion of AMPA receptors in the post-synaptic neuron
QuestionChoice
This is required in early-phase LTP before late-phase LTP occurs. Calcium entry activates CaMKII, which can now insert and phosphorylate AMPA receptors.
10000754
d
Calcium ion entry through NMDA receptors
QuestionChoice
This question is asking specifically about the late phase of LTP in the post-synaptic neuron.

Calcium-activated signal transduction activates new protein synthesis, recruiting new proteins to the synapse to cause morphological changes. These changes last for hours, days and months in late-phase LTP. Early phase LTP lasts minutes to an hour and is explained through the other options.
10000751
a
Protein synthesis and morphological changes
Concept
Chapter
2693
3820
Neuromuscular junction
Topic
152
Neuroscience
12697
What changes occur in the post-synaptic neuron in order to sustain late-phase long-term potentiation (LTP)?
a