QuestionSBA
QuestionChoice
This is a feature of myasthenia gravis, a disorder caused by dysfunctional nicotinic acetylcholine receptors.
10004674
d
It is often associated with thymomas or thymic hyperplasia
QuestionChoice
Lambert-Eaton syndrome is caused by antibodies directed against presynaptic voltage-gated calcium channels. This means that less acetylcholine can be released at the neuromuscular junction, commonly causing muscular weakness.
10004671
a
It is caused by antibodies directed against presynaptic voltage-gated calcium channels in the peripheral nervous system
QuestionChoice
Lambert-Eaton syndrome is commonly associated with small-cell lung cancer. It is occasionally seen alongside breast and ovarian cancers and can occur independently as an autoimmune disorder.
10004675
e
It is associated with non-small cell lung cancer
QuestionChoice
Extraocular and proximal muscle weakness are features of myasthenia gravis. Lambert-Eaton syndrome causes hyporeflexia and limb girdle weakness, affecting the lower limbs first.
10004672
b
Extraocular muscle weakness, resulting in diplopia
QuestionChoice
This is a feature of myasthenia gravis. Lambert-Eaton syndrome shows an incremental response to repetitive electrical stimulation on EMG.
10004673
c
EMG shows a diminishing response of muscle fibres with repetitive electrical stimulation
Concept
Chapter
2693
4316
Lambert-Eaton myasthenic syndrome
Topic
141
Neurology
13481
Which of the following is a feature of Lambert-Eaton myasthenic syndrome?
a