QuestionSBA
QuestionChoice
Vancomycin is a glycopeptide antibiotic and exerts its effect by binding to cell wall proteins, which prevents the formation of cross-links in the peptidoglycan cell wall. They do not act on the ribosomal 50s subunit of the bacterium to inhibit bacterial protein synthesis, making this answer incorrect.
10025748
d
Vancomycin
QuestionChoice
Amoxicillin belongs to the penicillin class of antibiotics. Penicillins exert their antimicrobial effect through the inhibition of penicillin-binding proteins. These are key in catalysing the reaction to make bacterial cell walls. They do not act on the ribosomal 50s subunit of the bacterium to inhibit bacterial protein synthesis, making this answer incorrect.
10025746
b
Amoxicillin
QuestionChoice
Clarithromycin is a macrolide antibiotic. Macrolides exert their effects through the inhibition of protein synthesis, by binding to the 50s subunit of the ribosome. This is therefore the correct answer.
10025745
a
Clarithromycin
QuestionChoice
Cefotaxime belongs to the cephalosporin class of antibiotics. Cephalosporins exert their effect through inhibiting the cross-linking of peptidoglycans in the cell wall. They do not act on the ribosomal 50s subunit of the bacterium to inhibit bacterial protein synthesis, making this answer incorrect.
10025747
c
Cefotaxime
QuestionChoice
Gentamicin is an aminoglycoside which inhibits bacterial protein synthesis by binding to the **30S subunit** of the ribosome. They do not act on the ribosomal 50s subunit of the bacterium to inhibit bacterial protein synthesis, making this answer incorrect.
10025749
e
Gentamicin
Concept
Chapter
2693
5861
Macrolides
Topic
223
Antibiotic pharmacology
17547
A 60 year old man is admitted to the respiratory ward for treatment of a lower respiratory tract infection. An antibiotic is commenced which acts on the ribosomal 50s subunit of the bacterium to inhibit bacterial protein synthesis.

Which of the following antibiotics is prescribed?
a