QuestionSBA
QuestionChoice
This is inflammation of the gallbladder and presents with a fever and positive Murphy's sign. A positive Murphy's sign is defined as a painful palpable gallbladder in the RUQ during inspiration. It is important to note that acute cholecystitis rarely presents with jaundice, therefore this answer is incorrect.
10004138
c
Acute cholecystitis
QuestionChoice
Biliary colic describes colicky right upper quadrant pain due to gallstones passing through the biliary tree. The pain is worse on eating and may radiate to the shoulder region. There is no jaundice or abnormal liver function tests in biliary colic.
10004140
e
Biliary colic
QuestionChoice
Clarithromycin is a type of macrolide which are known to be hepatotoxic. This patient and her LFTs show a cholestatic picture (extremely raised ALP) which occurred after the initiation of the antibiotic treatment. Therefore, this is a drug-induced cholestasis picture.
10004136
a
Drug-induced cholestasis
QuestionChoice
This is a benign inherited liver condition involving impaired processing of bilirubin. Patients may experience jaundice when due to elevated levels of bilirubin but additional LFTs should not be abnormal.
10004137
b
Gilbert's Syndrome
QuestionChoice
This involves inflammation of the pancreas. It is a life-threatening emergency and patients commonly present with severe epigastric pain radiating to the back and vomiting. The patient is not in any pain and therefore this diagnosis is unlikely.
10004139
d
Acute pancreatitis
Concept
Chapter
2693
4049
Jaundice
Topic
136
Gastroenterology
13374
A 37-year-old was recently admitted to the hospital and started on clarithromycin for pneumonia.

She was discharged, and 4 days later became itchy and noticed she was turning yellow. Her LFTs show:

 - ALP: 328
 - ALT: 67
 - GGT: 401
 - Bilirubin: 156.

Which of the following is the most likely cause of this clinical presentation?
a