QuestionSBA
QuestionChoice
Heparin does not directly act upon folate. Folate is a B vitamin that is vital for the production of functional red blood cells.
10007059
d
Folate
QuestionChoice
Heparin does not directly act upon thrombin. Dabigatran is an alternative anticoagulation medication that acts by inhibiting thrombin.
10007058
c
Thrombin
QuestionChoice
Heparin does not act directly upon dopamine. Dopamine is a neurotransmitter involved in neuronal signalling. It does not play a role in haemostasis.
10007060
e
Dopamine
QuestionChoice
This is correct. Heparin acts on antithrombin III, forming a complex that inhibits thrombin, factor Xa, IXa, XIa and XIIa. It has a short duration of action so can be terminated quickly with protamine sulfate.
10007056
a
Antithrombin III
QuestionChoice
Heparin does not act upon vitamin K. In fact, vitamin K is pro-thrombotic and would not be helpful in reducing a patient's thrombosis risk. Warfarin is a vitamin K antagonist that is commonly prescribed as an anti-coagulant.
10007057
b
Vitamin K
Concept
Chapter
2693
4564
Unfractionated heparin
Topic
203
Pharmacology of Haemostasis and Thrombosis
13958
A 68-year-old man with renal failure requires emergency cardiac surgery. After the procedure, he is given an anticoagulation medication to reduce his risk of thrombosis.

Which of the following biochemicals does heparin act upon?
a