QuestionSBA
QuestionChoice
This presentation is characteristic of acute pancreatitis. It is characterised by severe epigastric pain that may radiate to the back, as well as nausea and vomiting in some cases. Anti-CCP is a serum biomarker usually indicative of a patient suffering from rheumatoid arthritis. It is not typically raised in acute pancreatitis.
10025601
b
Anti-Cyclic Citrullinated Peptide (Anti-CCP)
QuestionChoice
This presentation is characteristic of acute pancreatitis. It is characterised by severe epigastric pain that may radiate to the back, as well as nausea and vomiting in some cases. Although hypocalcaemia is often seen in acute pancreatitis, it is not a specific marker for diagnostic purposes.
10025602
c
Hypocalcaemia
QuestionChoice
This presentation is characteristic of acute pancreatitis. ESR is a generic serum biomarker used to indicate inflammation. Whilst it may also be raised in acute pancreatitis, ESR is a less specific indicator of pancreatitis in comparison to serum amylase or lipase.
10025603
d
Erythrocyte sedimentation rate (ESR)
QuestionChoice
This presentation is characteristic of acute pancreatitis. ANA is a marker of a wide range of autoimmune diseases. It is not specifically associated with pancreatitis, particularly as the most likely underlying cause in this case is gallstones.
10025604
e
Antinuclear antibody (ANA)
QuestionChoice
This presentation is characteristic of acute pancreatitis. It is characterised by severe epigastric pain that may radiate to the back, as well as nausea and vomiting in some cases. This patient also demonstrates Grey-Turner's sign: bruising to the flank indicating retroperitoneal bleeding associated with acute pancreatitis. Gallstones are a known cause of acute pancreatitis, as is alcohol excess. An amylase three times the upper limit of normal is indicative of acute pancreatitis, making this the correct answer. Similarly, lipase is another sensitive and specific marker or acute pancreatitis.
10025600
a
Amylase
Concept
Chapter
2693
5853
Acute pancreatitis
Topic
161
Emergency Medicine
17518
A 38 year old male presents to the emergency department with sudden onset epigastric pain that radiates to his back. The pain is eased somewhat by leaning forward. On examination, he is extremely tender in the epigastric region and has extensive bruising alongside his right flank.

He has a past medical history of gallstone disease, but is otherwise well with no regular medications. He drinks moderate amounts of alcohol, around 10 units a week.

Which of the following biochemical markers are specifically elevated in the most likely underlying diagnosis?
a