QuestionSBA
QuestionChoice
ACE inhibitors have no effect on bronchial dilation or constriction.
10005673
c
Bronchoconstriction
QuestionChoice
This is the mechanism by which amlodipine (another antihypertensive) causes swollen ankles - a common side effect.
10005672
b
Dilation of blood vessels
QuestionChoice
This activates pro-inflammatory peptides (prostaglandins and substance P) and therefore a release of histamine, which causes a hypersensitivity cough.
10005671
a
Build up of bradykinin
QuestionChoice
This is a potential risk of ACE inhibitors. However, it does not cause a cough and also occurs due to the accumulation of bradykinin.
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d
Angioedema of upper airways
QuestionChoice
ACE inhibitors reduce protein loss in the urine. They are used to treat/prevent proteinuria.
10005675
e
Increased protein loss
Concept
Chapter
2693
4435
ACE inhibitors
Topic
188
Renal Pharmacology
13681
Coughing is a common side effect of ACE inhibitors.

Which of the following best describes the way in which they cause this side effect?
a