QuestionSBA
QuestionChoice
PPIs usually have an enteric coating to prevent activation in the mouth and in the stomach. PPIs are activated within the highly acidic pH of the stomach and enter the parietal cells
10009542
b
Their ability to dissolve readily within the mouth during the first process of digestion to allow immediate action upon reaching the stomach
QuestionChoice
PPIs are effective on their own. The use of NSAIDs is usually advised against when there is a need for taking a PPI
10009543
c
PPIs are most effective when taken with NSAIDs to help combat a peptic ulcer
QuestionChoice
Incorrect. Ranitidine is a H2-antagonist which can be used to treat symptoms of gastroesophageal reflux disease (GORD).
10015620
e
Ranitidine is an example of a PPI
QuestionChoice
PPIs are activated within the acidic environment of the stomach.
10009544
d
PPIs are activated within the alkaline environment of the duodenum; this allows them to enter the bloodstream and work
QuestionChoice
Correct answer
10009541
a
PPIs block gastric acid secretion by irreversibly binding to and inhibiting the proton pump (H+/K+ ATPase)
Concept
Chapter
2693
5349
Peptic Ulcer
Topic
192
Upper GI
14456
Which of the following is correct with respect to Proton Pump Inhibitors (PPI)?
a