QuestionSBA
QuestionChoice
DIC is a rare but serious condition characterised by inappropriate, systemic activation of coagulation pathways. Raised D dimer levels, reduced fibrinogen concentration, low platelet count and prolonged prothrombin time can therefore be seen. It is caused by the inappropriate activation of clotting pathways which causes widespread coagulation. In turn, this depletes coagulation factors which then results in excessive bleeding.
10002092
a
Elevated D dimer levels, reduced fibrinogen concentration, low platelet count, prolonged prothrombin time
QuestionChoice
A high fibrinogen concentration is not seen in DIC: excessive widespread coagulation depletes fibrinogen levels. A high platelet count is not typical in DIC, and prothrombin time is prolonged.
10002096
e
Elevated D-dimer levels, high fibrinogen concentration, high platelet count, normal prothrombin time
QuestionChoice
In DIC, the platelet count is typically low, not high. Furthermore, D dimer is high, and prothrombin time (PT) is prolonged due to a depletion in coagulation factors.
10002094
c
Reduced D-dimer levels, reduced fibrinogen concentration, high platelet count, reduced prothrombin time
QuestionChoice
A high fibrinogen concentration is not seen in DIC: excessive widespread coagulation depletes fibrinogen levels. A prolonged prothrombin time would also be seen due to the depletion of coagulation factors. D dimer is also raised.
10002093
b
Reduced D-dimer levels, high fibrinogen concentration, low platelet count, normal prothrombin time
QuestionChoice
A high fibrinogen concentration is not seen in DIC: excessive widespread coagulation depletes fibrinogen levels.
10002095
d
Elevated D-dimer levels, high fibrinogen concentration, low platelet count, prolonged prothrombin time
Concept
Chapter
2693
3930
disseminated intravascular coagulation
Topic
157
Haematology
12965
Disseminated intravascular coagulation (DIC) is a disorder of coagulation in which changes to D dimer and fibrinogen levels are seen.

Which of the following best describes the D dimer and fibrinogen profile seen in DIC?
a