QuestionSBA
QuestionChoice
D-dimer is high in DIC because it is a fibrin degradation product and fibrinolysis occurs in DIC.
10001439
c
Low platelets, low fibrinogen, raised APTT, low d-dimer
QuestionChoice
APTT is raised in DIC because fibrinolysis is taking place. Fibrinogen and fibrin are key components of the intrinsic clotting pathway, therefore the consumption of these clotting products in DIC results in a prolonged APTT.
10001440
d
Low platelets, low fibrinogen, normal APTT, low d-dimer
QuestionChoice
Fibrinogen is low in DIC because fibrinolysis is activated which results in the consumption of fibrin and fibrinogen.
10001441
e
Low platelets, high fibrinogen, raised APTT, raised d-dimer
QuestionChoice
Platelets are low in DIC because the activation of the clotting pathway leads to excess thrombus formation which consumes platelets.
10001438
b
High platelets, low fibrinogen, raised APTT, raised d-dimer
QuestionChoice
This patient has DIC. In DIC, the coagulation pathway is activated throughout the body which consumes platelets and clotting factors and leads to a low platelet count. Fibrinogen is low because fibrinolysis is activated, and d-dimer is high as it is a fibrin degradation product.
10001437
a
Low platelets, low fibrinogen, raised APTT, raised d-dimer
Concept
Chapter
2693
3930
disseminated intravascular coagulation
Topic
157
Haematology
12834
A 42-year-old male is admitted to the hospital with sepsis following surgery for colorectal cancer.

His respiratory rate is 25, oxygen saturations are 92%, heart rate is 120bpm, and temperature is 38.2.

On examination, he is not oriented to time and place, and a purpuric rash is noted over his arms. There is also blood oozing from his cannula sites. His past medical history is unremarkable.

Which of the following is most likely to be his blood results?
a