QuestionSBA
QuestionChoice
Although both methotrexate and cefotaxime increase likelihood of nephrotoxicity, it is not contraindicated.
10003128
c
Cefotaxime
QuestionChoice
There are no drug-drug interactions between nitrofurantoin and methotrexate.
10003127
b
Nitrofurantoin
QuestionChoice
Both trimethoprim and methotrexate inhibit dihydrofolate reductase in folic acid metabolism. When prescribed together, they can lead to bone marrow suppression. Hence, trimethoprim is absolutely contraindicated in this patient.
10003126
a
Trimethoprim
QuestionChoice
There are no drug-drug interactions between clarithromycin and methotrexate.
10003130
e
Clarithromycin
QuestionChoice
Although both methotrexate and vancomycin increase the likelihood of nephrotoxicity, it is not absolute contraindicated.
10003129
d
Vancomycin
Concept
Chapter
2693
3936
Methotrexate
Topic
146
Rheumatology
13172
A 27-year-old female is on methotrexate for rheumatoid arthritis.

Which of the following medications is absolutely contraindicated in this patient?
a