QuestionSBA
QuestionChoice
Hallucinations are a very rare side effect of enteral use of gentamicin.
50357
d
She should report any hallucinations she experiences
QuestionChoice
The frequency of vertigo occurring as a result of gentamicin treatment is unknown, therefore it is not something the patient needs to be told is likely to occur.
50355
b
She is likely to experience vertigo when taking gentamicin
QuestionChoice
Gentamicin can cause drug induced nephrotoxicity. In patients with CKD however it is safe to use if it is used in the short term or at a reduced dosage. Gentamicin is thought to mainly contribute to a reduction in renal function in part due to apoptosis of proximal convoluted tubule cells.
50354
a
Although this drug can cause acute kidney injury, it is safe to use in patients with chronic kidney disease
QuestionChoice
Thyroid function is not routinely monitored in patients taking gentamicin.
50356
c
She will need to have her thyroid function regularly monitored
QuestionChoice
Depression is a very rare side effect of gentamicin.
50358
e
She is likely to experience changes to her mood when on gentamicin
QuestionComment
where could i find this info in the BNF ?
60867
User
subscriber
Axillary Metabolism 
QuestionComment
gentamicin page in important safety information - 'To minimise the risks of adverse effects, continuous monitoring of renal and auditory function, as well as hepatic and laboratory parameters, is recommended for all patients.'
61366
User
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Patient Power
QuestionComment
A genuine question, i would appreciate some help. Would a doctor actually tell a patient "Although this drug can cause acute kidney injury, it is safe to use in patients with chronic kidney disease" ?  
61550
QuestionComment
Given she has CKD it might be something she's worried about in which case yes but weird thing to pick as an exam Q 
61709
User
subscriber
Epidermis Benign
User
subscriber
han
QuestionComment
worth noting that dizziness is a common side effect of gent and patients often wont differentiate between those two
61670
User
subscriber
Vaccine Complement
QuestionComment
how is that important advice, i dont think the patient would care
61733
User
subscriber
Kawasaki Pudendal
Concept
Chapter
Osteoporosis, otherwise known as thin bones, is a condition associated with high risk of low trauma fractures due to reduced bone mineral density. Osteoclast activity exceeds osteoblast activity, meaning that bone resorption is occurring at a greater rate than bone formation.

**Symptoms and Signs**

- Generally asymptomatic until a fragility fracture occurs
- Back pain
- Kyphosis (stooped posture)
- Fragility fractures

**Risk factors**

- Female sex
- Increasing age
- Smoking
- Corticosteroid use
- Low BMI (< 20-25kg/m<sup>2</sup>)
- Low body weight (<58kg)
- Vitamin D deficiency

**Protective factors**

- Higher BMI
- Exercise - mechanical loading stimulates bone formation

**Diagnosis**
Osteoporosis can be detected on dual-energy x-ray absorptiometry (DEXA) scan.
A T score of < -2.5 indicates osteoporosis

**Management**

- Fall prevention
- Vitamin D and calcium supplementation
- Hormone replacement therapy (postmenopausal women)
- Oral bisphosphonates
2657
3654
Gentamicin is safe to take in patients with chronic kidney disease
Topic
13
Neurosurgery
10125
Case presentation: A 34-year-old woman attends the emergency department with abdominal pain, dysuria and rigors.


**Observations**

* Heart rate: 84 bpm
* Respiratory rate: 14
* Blood pressure: 111/84 mmHg
* Temperature: 38.2 degrees celsius
* Oxygen saturations: 97% on room air

**PH**
Chronic kidney disease stage II

**DH**
Nil

**Investigations**
Urine dip:

* Nitrates ++
* White blood cells ++
* Red blood cells -

Urine pregnancy test -ve

It is decided based on her presentation she has pyelonephritis, and she is due to be commenced on IV gentamicin. She is expected to be on antibiotics for a number of days. She has been reading about gentamicin online, and has some concerns given her past medical history.

Question: Select the most important information that should be provided for this patient.
a