QuestionSBA
QuestionChoice
This answer is correct. In rheumatoid arthritis, there is pannus formation where there is hyperplasia of the subintima and synovial lining of joint capsules. The pannus is full of inflammatory cells which erode the articular cartilage and underlying bone.
10007376
a
Pannus formation
QuestionChoice
This answer is incorrect. In rheumatoid arthritis, there is a higher volume of synovial fluid. This is due to cytokine release which causes capillaries near the synovial surface to leak more fluid.
10007380
e
Reduced volume of synovial fluid
QuestionChoice
This answer is incorrect. In rheumatoid arthritis, there is decreased synovial fluid viscosity due to the degradation of hyaluronate. The concentration of hyaluronate is proportional to the synovial fluid viscosity, so with reduced hyaluronate, the fluid is less viscous.
10007377
b
Increased synovial fluid viscosity
QuestionChoice
This answer is incorrect. Neutrophils are the most predominant cell type in synovial fluid in rheumatoid arthritis. Lymphocytes are the most predominant cell type in the subintima.
10007378
c
Predominantly lymphocytes in synovial fluid
QuestionChoice
This answer is incorrect. In rheumatoid arthritis, there is increased osteoclast activity and reduced osteoblast activity, leading to net destruction of bone.
10007379
d
Increased osteoblast activity
Concept
Chapter
2693
3975
Rheumatoid Arthritis
Topic
146
Rheumatology
14022
A 53-year-old woman is referred to a rheumatologist by her GP with suspected rheumatoid arthritis affecting the joints of her hands, feet, and knees.

Which of the following is most likely to be present in the joints of this patient?
a