QuestionSBA
QuestionChoice
These are general symptoms often seen in both haematological and non-haematological malignancy, but would not specifically point to a diagnosis of Hodgkin’s lymphoma.
10027154
d
Anaemia, fever, weight loss, lymphadenopathy
QuestionChoice
Hodgkin’s lymphoma is a malignant proliferation of lymphocytes, the pathological hallmark of which is the Reed-Sternberg cell- a giant, multinucleate cell derived from B lymphocytes. The other features listed above are also classically seen in Hodgkin’s lymphoma.
10027151
a
Reed-Sternberg cells, lymphadenopathy, weight loss, splenomegaly
QuestionChoice
These are features seen in acute promyelocytic leukaemia. This is a subtype of acute myeloid leukaemia seen in younger patients and generally carries a good prognosis.
10027155
e
Disseminated intravascular coagulation, Auer rods, PML/RARa gene fusion
QuestionChoice
These are features of chronic myeloid leukaemia, another type of haematological malignancy. The presence of the Philadelphia chromosome, a shortened chromosome 22 containing an abnormal BCR-ABL fusion gene, is the Gold standard of CML diagnosis.
10027152
b
Philadelphia chromosome, splenomegaly, leucocytosis, severe anaemia
QuestionChoice
These are features of multiple myeloma, a haematological malignancy involving neoplastic proliferation of monoclonal plasma cells in the bone marrow.
10027153
c
Hypercalcaemia, anaemia, renal insufficiency, bone pain, high free serum light chains
Concept
Chapter
2693
5960
Hodgkin's lymphoma
Topic
157
Haematology
17828
Which set of findings would most likely point to a diagnosis of Hodgkin’s lymphoma?
a