QuestionSBA
QuestionChoice
Incorrect. This is the mechanism of intestinal alpha-glucosidase inhibitors such as acarbose
10002890
e
Delay intestinal carbohydrate absorption
QuestionChoice
Correct. This is the mechanism of biguanides, of which metformin is an example of.
10002886
a
Increase peripheral insulin sensitivity and hepatic glucose uptake
QuestionChoice
Incorrect. This is the mechanism of GLP1 analogues such as evenatide
10002889
d
Increase insulin secretion and sensitivity
QuestionChoice
Incorrect. This is the mechanism of sulfonureas such as gliclazide
10002887
b
Depolarise islet cells in the pancreas increasing insulin release
QuestionChoice
Incorrect. This is the mechanism of SGLT2 inhibitors such as dapgliflozin
10002888
c
Increase urinary glucose loss
Concept
Chapter
2693
4071
Anti-diabetic drugs mechanisms of action
Topic
133
Endocrinology
13124
A 43 year old male has been recently diagnosed with type 2 diabetes mellitus.

Diet and lifestyle modifications have been attempted but these don't control his symptoms so is given metformin.

What is the mechanism of metformin?
a