QuestionSBA
QuestionChoice
Susceptibility bias refers to the phenomenon in which a particular group of individuals within a study population may have a higher or lower susceptibility to the condition or outcome under investigation. It is unrelated to the way participants are recruited into the study but rather how certain factors or characteristics may make some participants more or less likely to develop the condition or experience the outcome.
10025466
b
Susceptibility bias
QuestionChoice
Exclusion bias refers to the phenomenon whereby the researchers intentionally remove important variables or factors that should be included in the analysis from the model. For example, if the researchers purposely exclude some subgroups from the sample population. This is not the best answer because for this context because the researchers in this trial are not actively removing subgroups of participants from the clinical trial.
10025467
c
Exclusion bias
QuestionChoice
Attrition bias refers to the phenomenon where there is a systematic loss of participants or data throughout the study. This loss of participants to follow up eventually leads to systematic differences between groups and thus unrepresentative samples. This is not the best answer for this context because it does not mention attrition of data or any participant dropouts.
10025468
d
Attrition bias
QuestionChoice
Time interval bias refers to the phenomenon whereby researchers intentionally change a specified range of time or duration to support their desired findings. For example, when there is a discrepancy in the timing and duration of follow-up or observation between different study groups or exposure levels, it can lead to a distortion of the observed relationships or outcomes in the study. Although this is a type of selection bias, it does not fit this vignette.
10025469
e
Time interval bias
QuestionChoice
This is the correct answer. By using only online mediums, this study primarily attracts tech-savvy, younger individuals who are active online and on social platforms. This is also known as convenience sampling. The trial excludes older adults and individuals with limited internet access. Therefore, the selection of participants for this clinical trial is not representative of the broader population or the specific patient group of interest, introducing sampling bias.
10025465
a
Sampling bias
Concept
Chapter
2693
4470
Selection Bias
Topic
178
Medical Statistics
17491
A pharmaceutical company is conducting a clinical trial to test the effectiveness of a new medication for Type 2 diabetes. To recruit participants for the study, they decide to advertise the trial exclusively through online platforms and social media.

Which of the following forms of selection bias could affect the validity of this trial?
a