QuestionSBA
QuestionChoice
This woman has Addison's disease - this is an autoimmune condition that damages the adrenal gland.

This leads to a reduction in the production of aldosterone and cortisol (mineralocorticoids).

Cortisol is a glucocorticoid and is formed from the middle area of the adrenal gland called the zona fasiculata.

This disease can lead to symptoms as described in this case; depression, weight loss, nausea, hyperpigmentation and weight loss.
10005946
a
Zona fasiculata
QuestionChoice
This is the outer zone of the cortex of the adrenal gland this is reponsible for secreting mineralocorticoids such as aldosterone.
10005947
b
Zona glomerulosa
QuestionChoice
The adrenal capsule surrounds the adrenal gland and ensures that the damaged cells are replaced and the integrity of the gland is maintained.
10005949
d
capsule
QuestionChoice
This is the inner most layer of the adrenal gland that secretes androgens such as estrogens and testosterone
10005948
c
Zona reticularis
QuestionChoice
This is the innermost part of the adrenal gland. This releases epinephrine (adrenaline) and norepinephrine (noradrenaline).

These hormones are important in autonomic functions such as regulating heart rate and plays a crucial role in the fight or flight response.
10005950
e
Medulla
Concept
Chapter
2693
3812
Adrenal cortical hormones
Topic
167
Endocrine physiology
13736
A 40 year old woman presents to accident and emergency with severe nausea and abdominal pain.

It is noticed by the nurse that she appears dehydrated and has some tanning of the skin.

The patient says that for the past few weeks she has lost weight and feels really low and hasn't got out of bed most days.

She is found to have a low cortisol level in her blood.

What part of the adrenal gland produces cortisol?
a