QuestionSBA
QuestionChoice
5-lipooxygenase catalyses the conversion of arachidonic acid into 5-HpETE. It is involved in the production of leukotrienes.
10026953
c
5-lipooxygenase
QuestionChoice
Cyclo-oxygenase (COX) enzymes 1 and 2 catalyse the conversion of arachidonic acid into prostaglandin H2. NSAIDs are COX inhibitors and prevent the production of prostaglandin H2 and downstream inflammatory mediators.
10026951
a
Cyclo-oxygenase enzymes 1 and 2
QuestionChoice
Thromboxane synthase catalyses the formation of thromboxane from prostaglandin H2
10026955
e
Thromboxane synthase
QuestionChoice
Cytochrome P450 is a hepatic enzyme that catalyses the breakdown of many NSAIDs, such as ibuprofen
10026954
d
Cytochrome P450
QuestionChoice
Phospholipase A2 catalyses the conversion of phospholipids into arachidonic acid in response to injury.
10026952
b
Phospholipase A2
Concept
Chapter
2693
5939
NSAIDs
Topic
195
Pharmacology
17788
Arachidonic acid is an essential fatty acid that is used in the synthesis of prostaglandins, leukotrienes and thromboxane. Non-steroidal anti-inflammatory drugs inhibit its conversion into these inflammatory mediators.

Which enzyme do NSAIDs inhibit?
a