QuestionSBA
QuestionChoice
This is incorrect because of decreased prostaglandin generation means less sensitisation of nociceptive nerve endings
10009764
e
The analgesic effect of NSAIDs causes a decrease in prostaglandin generation and means a higher degree of sensitisation of nociceptive nerve endings
QuestionChoice
This is incorrect as NSAIDs will decrease vasodilation and decrease oedema
10009761
b
The anti-inflammatory action of NSAIDs decreases prostaglandins and increases vasodilation and oedema
QuestionChoice
This is incorrect, as NSAIDs are non-selective and inhibit prostaglandin biosynthesis by direct action on both COX-1 and COX-2
10009762
c
NSAIDs inhibit prostaglandin biosynthesis by direct action exclusively on COX-2 enzymes
QuestionChoice
This is incorrect as COX-1 enzymes are involved in tissue homeostasis, whereas the description above describes COX-2 enzymes
10009763
d
COX-1 enzymes are induced in activated inflammatory cells and responsible for the production of prostaglandin mediators of inflammation
QuestionChoice
This is the correct answer
10009760
a
In the antipyretic effect of NSAIDs inhibition of COX-2 prevents inflammatory mediators such as Interleukin-1 from increasing prostaglandins in the central nervous system which in turns prevents the elevation of the hypothalamic point for temperature control.
Concept
Chapter
2693
5386
NSAIDs
Topic
141
Neurology
14500
In regards to NSAIDs, which of the following statements is correct?
a