QuestionSBA
QuestionChoice
Gingival hyperplasia is an uncommon side effect of all calcium channel blockers
34266
b
Gingival hyperplasia
QuestionChoice
Hyperglycaemia is a rare or very rare side effect of amlodipine
34267
c
Hyperglycaemia
QuestionChoice
Peripheral neuropathy is a rare or very rare side effect of amlodipine
34269
e
Peripheral neuropathy
QuestionChoice
Peripheral oedema is a common or very common side effect of all calcium channel blockers. It is thought to be caused by arteriolar dilation that leads to increasing capillary pressure and extravasation of fluids into the surrounding tissues
34265
a
Peripheral oedema
QuestionChoice
Increased muscle tone is a rare or very rare side effect of amlodipine
34268
d
Increased muscle tone
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

2618
2796
Amlodipine side effects
Topic
92
General Practice
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Case presentation: A 40-year-old man visits his GP for medication review.  

PMH: Diabetes Mellitus, Hypertension
DH: Metformin Hydrochloride 500 mg PO TDS, Captopril 75 mg PO BD
Observations: Temperature 36.5, Respiratory rate 14, Blood pressure 165/95, Heart rate 76, Oxygen saturation 100% (on air)
The patient is advised to add Amlodipine 5 mg PO OD to his current treatment regime in view that his blood pressure is not well controlled

Question: Select the adverse effect that is most likely to be caused by this treatment
a