QuestionSBA
QuestionChoice
Prolactinomas are the most common hormone-secreting tumours from the pituitary gland. However, there are no features to suggest this in this case, except for the bitemporal hemianopia which is a result of the tumour itself, not the hormone it is secreting. If a tumour is secreting prolactin, there may be galactorrhea, erectile dysfunction and oligomenorrhea.
10027877
b
Prolactin
QuestionChoice
TSH is made in the anterior pituitary so could be produced in a pituitary adenoma. However, there are no features of hypothyroidism that would indicate excess TSH. These features may include weight gain, low mood, and fatigue.
10027878
c
Thyroid-stimulating hormone (TSH)
QuestionChoice
ACTH stimulates the adrenal gland to produce cortisol, therefore excess cortisol would result in Cushing's syndrome. Features of Cushing's syndrome include abdominal obesity, rounding of the face and purple striae on the abdomen. An ACTH-secreting pituitary adenoma is also called Cushing's disease.
10027880
e
Adrenocorticotrophic hormone (ACTH)
QuestionChoice
This patient has features of acromegaly (large hands and more prominent facial features). Acromegaly is caused by excess growth hormone.
10027876
a
Growth hormone
QuestionChoice
Oxytocin is produced by the hypothalamus and then secreted by the posterior pituitary gland. Therefore, it could not be produced in excess by a pituitary adenoma.
10027879
d
Oxytocin
Concept
Chapter
2693
6013
Growth hormone (GH)
Topic
167
Endocrine physiology
17973
A 64-year-old man presents with a headache, which has been going on for a few months now. Over this time, he also mentions he is bumping into doorways in his home. On examination, you note large hands and large prominent facial features. He states that his wife thinks he looks different in recent years. An MRI head reveals a pituitary adenoma.

Given the clinical picture, which hormone is being secreted?
a