QuestionSBA
QuestionChoice
Metformin is contraindicated in those with a low eGFR.
10005136
a
Metformin
QuestionChoice
These reduce glucose reabsorption and increase urinary glucose excretion. These are used as monotherapy if metformin is inappropriate or with other antidiabetic drugs.
10005139
d
SGLT2 inhibitors e.g. canagliflozin
QuestionChoice
These increase insulin secretion and lower glucagon secretion.
This is used as monotherapy if metformin is inappropriate or with other antidiabetic drugs.
10005138
c
Incretins e.g. linagliptin
QuestionChoice
These are utilised when there is some residual pancreatic beta-cell activity. Care should be taken when prescribing to the elderly. Contraindications include those with acute pyphorias for gliclazide, or anyone with DKA for all sulphonylureas.
10005140
e
Sulphonylureas e.g. gliclazide
QuestionChoice
This is used as monotherapy if metformin is inappropriate or in combination with metformin or sulphonylureas.
10005137
b
Pioglitazone
Concept
Chapter
2693
4376
Metformin
Topic
220
Endocrine Pharmacology
13574
A 67-year-old female presents to the hospital with complaints of fatigue, increased thirst, and increased frequency of urination. She has an eGFR of 23 mL/minute/1.73 m<sup>2</sup> and is found to be a type 2 diabetic.

Which one of the following drugs would be unsuitable to use when treating this patient?
a