QuestionSBA
QuestionChoice
Donepezil can be prescribed in the form an orodispersible tablet. The tablet should be placed on the tongue, allowed to disperse and swallowed
34112
c
Donepezil orodispersible tablet should be chewed and placed below the tongue to allow easy absorption
QuestionChoice
It is important to remind patients to refrain from drinking alcohol while taking donepezil because alcohol can reduce the effectiveness of donepezil and increase the risk of side effects
34113
d
He can drink alcohol while taking donepezil
QuestionChoice
Non-steroidal anti-inflammatory drugs (NSAIDs) should be taken with caution because concurrent usage of NSAID and donepezil may increase risk of ulceration
34114
e
He can take over-the-counter anti-inflammatory painkillers such as ibuprofen without consulting a health professional first
QuestionChoice
Donepezil is a reversible cholinesterase inhibitor that is used to manage mild to moderate Alzheimer’s disease. It helps to alleviate some symptoms like being forgetful or confused but does not completely cure Alzheimer’s disease
34111
b
Donepezil is a glutamate receptor antagonist that is used to treat mild-to-moderate Alzheimer’s disease
QuestionChoice
Most common side effects of donepezil include diarrhoea, headache and nausea. Through accumulation of acetylcholine at muscarinic receptors, donepezil causes diarrhoea by increasing the gastrointestinal motility
34110
a
Diarrhoea is a common side effect of donepezil
QuestionComment
The BNF does not mention alcohol.
8507
User
subscriber
Juice Myopathy
QuestionComment
I can't find where it says about NSAIDs and donepezil in the BNF?
17100
User
subscriber
Contusion Hallux
Concept
Chapter
#### Monitoring

The BNF advises to monitor lung function (in patients with a history of obstructive airway disease).

#### Overdoses

Overdosages with beta-blockers may cause cardiac effects such as bradycardia, hypotension, syncope, conduction abnormalities, and heart failure. Bradycardia is the most common arrhythmia, but some beta-blockers may induce ventricular tachyarrhythmias secondary to prolongation of QT interval (e.g. sotalol) or QRS duration (e.g. propranolol).
Non-cardiovascular effects include central nervous system effects (including drowsiness, confusion, convulsions, hallucinations, and in severe cases coma), respiratory depression, and bronchospasm.

Management
 - Airway protection 
 - Activated charcoal within 1 hour
 - IV Fluids
 
IV glucagon is the first-line management.
 
For symptomatic bradycardia, IV atropine may be used.

2618
2766
Donepezil
Topic
74
Elderly Care
6833
Case presentation: A 65-year-old woman attends the memory clinic with a six-month gradual onset memory decline. Her children report that she has been misplacing items and appears to be disoriented at times. The patient denies being low in mood, feeling tired or having any problems deriving joy from her hobbies.  

Physical examination: HS 1+11 + 0, chest clear with no added lung sounds, abdomen SNT, normal neurological exam
Investigation: Mini Mental State Examination (MMSE) score is 20/30.
She is advised to commence treatment with Donepezil Hydrochloride 5mg PO daily.

Question: Select the most important information that should be provided for this patient.
a